Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Guy C M, Grinwis"'
Autor:
Elpetra P. M. Timmermans, Joëlle Blankevoort, Guy C. M. Grinwis, Sietske J. Mesu, Ronette Gehring, Patric J. D. Delhanty, Peter E. M. Maas, Ger J. Strous, Jan A. Mol
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1381 (2024)
Background: The activation of the growth hormone receptor (GHR) is a major determinant of body growth. Defective GHR signaling, as seen in human Laron dwarfism, resulted in low plasma IGF-1 concentrations and limited growth, but also marked absence i
Externí odkaz:
https://doaj.org/article/5b4489a9c71247ea899d31c04259ad42
Autor:
Vanessa Alf, Yvet Opmeer, G. Diane Shelton, Guy C. M. Grinwis, Kaspar Matiasek, Marco Rosati, Paul J. J. Mandigers
Publikováno v:
Animals, Vol 14, Iss 17, p 2519 (2024)
Earlier, we described a breed-specific inflammatory myopathy in Dutch Kooiker dogs (Het Nederlandse Kooikerhondje), one of the nine Dutch breeds. The disease commonly manifests itself with clinical signs of difficulty walking, muscle weakness, exerci
Externí odkaz:
https://doaj.org/article/eb2bf37bd4d648b3adfa219a83458ff4
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
A 15-year-old spayed female domestic shorthaired cat was evaluated for chronic progressive paraparesis and proprioceptive ataxia. Neurological examination was consistent with a T3–L3 myelopathy. Plain thoracolumbar vertebral column radiographs and
Externí odkaz:
https://doaj.org/article/fea40908034a4f8c8e79611f140c451b
Autor:
Martijn Beukers, Guy C. M. Grinwis, Johannes C. M. Vernooij, Lisanne van derHoek, Anna R. Tellegen, Björn P. Meij, Stefanie Veraa, Dino Samartzis, Marianna A. Tryfonidou, Frances C. Bach
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Abstract Background Chronic low back pain, a leading contributor to disease burden worldwide, is often caused by intervertebral disc (IVD) degeneration. Modic changes (MCs) are MRI signal intensity changes due to lesions in vertebral bone marrow adja
Externí odkaz:
https://doaj.org/article/fb5d475e0b13418d8d7f2ea7a5d5e74d
Autor:
Marit F. van denBerg, Hans S. Kooistra, Guy C. M. Grinwis, Sebastiaan A. vanNimwegen, Martijn vanFaassen, Ido P. Kema, Erik Teske, Sara Galac
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 1, Pp 173-183 (2023)
Abstract Background Measurement of free metanephrines is recommended for screening of pheochromocytoma (PCC) but requires appropriate reference intervals (RIs). Hypothesis/Objectives To report RIs for plasma, urinary and salivary concentrations of fr
Externí odkaz:
https://doaj.org/article/34f712b9282846bdaca4e185e8071eec
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background We previously reported a familial thyroid follicular cell carcinoma (FCC) in a large number of Dutch German longhaired pointers and identified two deleterious germline mutations in the TPO gene associated with disease predispositi
Externí odkaz:
https://doaj.org/article/4afc27dddf094770a35850ae4446e511
Autor:
Marit F. van den Berg, Hans S. Kooistra, Guy C. M. Grinwis, Stefano Nicoli, Stefania Golinelli, Lisa Stammeleer, Monique E. van Wolferen, Elpetra P. M. Timmermans-Sprang, Maurice M. J. M. Zandvliet, Frank G. van Steenbeek, Sara Galac
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Pheochromocytomas and paragangliomas (PPGLs) are neuroendocrine tumors arising from the chromaffin cells in the adrenal medulla and extra-adrenal paraganglia, respectively. Local invasion, concurrent disorders, and metastases prevent surgical removal
Externí odkaz:
https://doaj.org/article/ca944eb626eb4e2cbd95c12dc7d0b599
Autor:
Kirsten L. van Bokhorst, Sara Galac, Hans S. Kooistra, Janny C. de Grauw, Erik Teske, Guy C. M. Grinwis, Sebastiaan A. van Nimwegen
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Adrenalectomy is the treatment of choice in case of functional adrenal tumors and malignant adrenal incidentalomas. Laparoscopic adrenalectomy (LA) in dogs has gained popularity in recent years, however, clinical studies on large patient populations
Externí odkaz:
https://doaj.org/article/9acc7676d195483ca557eac3ad9dae89
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
A 3.5-year-old male intact Staffordshire terrier crossbreed dog was presented with a one-week history of progressive paraparesis with fecal and urinary incontinence. Neurological examination was consistent with a T3-L3 myelopathy. A magnetic resonanc
Externí odkaz:
https://doaj.org/article/68f2e5e6aae248a8a46e1bd2a8a93beb
Autor:
Alicia Ruppelt, Iris Pijnenburg, Claire Pappers, Roos-Anne Samsom, Linda Kock, Guy C. M. Grinwis, Bart Spee, Marco Rasponi, Marco Stijnen
Publikováno v:
Journal of International Medical Research, Vol 51 (2023)
Objectives The success of the ex vivo machine perfusion of pig livers used for preclinical research depends on organ quality and availability. In this study, we investigated whether livers obtained from slaughterhouses are suitable and equivalent to
Externí odkaz:
https://doaj.org/article/71a0c16bc1df4bd097e5bca873720c20