Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Guy Bouchard"'
Publikováno v:
BMC Clinical Pathology, Vol 18, Iss 1, Pp 1-6 (2018)
BMC Clinical Pathology
BMC Clinical Pathology
Background Measuring expression profiles of inflammatory biomarkers is important in monitoring the polarization of immune responses; therefore, results should be independent of quantitation methods if they are to be accepted as validated clinical pat
Autor:
David T. White, Naijia Huang, Jeffrey S. Tan, Kenneth J. Ruterbories, Jason Liu, Derek Brocksmith, Lee J. Burns, Alain Stricker-Krongrad, Nathan Yumibe, Nita J. Patel, Guy Bouchard
Publikováno v:
International Journal of Pharmacokinetics. 2:81-91
Aim: Oral and intravenous pharmacokinetic (PK) studies were conducted in four different minipig strains: Sinclair, Yucatan, Hanford and Göttingen after administration of metformin or R,S-verapamil (R,S-VER). Results: The results indicated that the P
Autor:
Chris Hanks, Shayne C. Gad, Jason Liu, Amber Fuller, Derek Brocksmith, Miao Zhong, Guy Bouchard, Catherine Shoemake, David T. White, Alain Stricker-Krongrad
Publikováno v:
International Journal of Toxicology. 36:113-123
A functional observational battery (FOB) is recommended as the first-tier neurotoxicity screening in the preclinical safety pharmacology testing guidelines. Minipigs have increasingly been used in regulatory toxicology studies; however, no current FO
Publikováno v:
Toxicologic Pathology. 44:612-623
The use of the miniature swine as a nonrodent species in research has continued to expand for over a decade, and they are becoming routinely used both in experimental pharmacology and as a therapeutic model for human diseases. Miniature swine models
Autor:
Shayne C. Gad, Marcia E. Pereira, Guy Bouchard, Catherine Shoemake, Alain Stricker-Krongrad, Derek Brocksmith
Publikováno v:
Toxicologic Pathology. 44:421-427
The use of miniature swine as a nonrodent species in safety assessment has continued to expand for over a decade, and they are becoming routinely used in toxicology and in pharmacology as well as a model for human diseases. Miniature swine models are
Publikováno v:
Diabetes. 67
Abundant evidence shows that patients with type 1 diabetes are at high risk for several cardiovascular disorders. Our objective was to assess cardiac electro-pathophysiology changes linked to chronic insulin-dependent diabetes in the Yucatan miniatur
Autor:
Guy Bouchard
Face à la défense aristotélicienne de l'esclavage, il faut, dit-on, « sauver l'honneur des philosophes ». Objectif : dévoiler le prix de cette entreprise dans un contexte où l'on préconise de plus en plus le recours à Aristote pour surmonter
Publikováno v:
The Clinical Chemistry of Laboratory Animals ISBN: 9781315155807
The Clinical Chemistry of Laboratory Animals
The Clinical Chemistry of Laboratory Animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73c2e0382a9e3ae8ae9fc35453729645
https://doi.org/10.1201/9781315155807-5
https://doi.org/10.1201/9781315155807-5
Autor:
Alain Stricker-Krongrad, Catherine Shoemake, Derek Brocksmith, Jason Liu, Robert Hamlin, Guy Bouchard
Publikováno v:
Toxicology Research and Application, Vol 1 (2017)
The minipig has been increasingly recognized as a valid alternative to canines and nonhuman primates in regulatory toxicity. This article presents the results of cardiovascular assessments in the Yucatan, Hanford, Sinclair, and Göttingen minipigs co
Autor:
David White, Paul Donald Forbes, Guy Bouchard, Larry D. Brown, Jason Liu, Dean R. Wehmeier, Dae Young Kim, Charles F. Lawson, Heinz Leigh
Publikováno v:
Photodermatology, Photoimmunology & Photomedicine. 28:34-41
Summary Background/Purpose This study determined the threshold doses for ‘solar erythema’ and for phototoxic responses to 8-methoxypsoralen (8-MOP) in white skin Hanford and grey skin Yucatan miniature swine. Methods For threshold erythema determ