Expression of matrix metalloproteinases in Naegleria fowleri and their role in invasion of the central nervous system

Autor: Guy A. Cabral, Ana Maris Carlesso, Francine Marciano-Cabral, Charlton Lam, Melissa Jamerson

Publikováno v: Microbiology. 163:1436-1444

Naegleria fowleri is a free-living amoeba found in freshwater lakes and ponds and is the causative agent of primary amoebic meningoencephalitis (PAM), a rapidly fatal disease of the central nervous system (CNS). PAM occurs when amoebae attach to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9b5915f14ed64045e0799c84c73533
https://doi.org/10.1099/mic.0.000537

Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Autor: Ruth A. Ross, Pierre Casellas, Ben Cravatt, Ken Mackie, William Devane, George Kunos, Mary E. Abood, Peter J. Greasley, Tom I. Bonner, Heather B. Bradshaw, Raphael Mechoulam, Allyn C. Howlett, Guy A. Cabral, Miles Herkenham, Francis Barth, Stephen P.H. Alexander, Maurice R. Elphick, Christian C. Felder, Roger G. Pertwee, Vincenzo Di Marzo

Publikováno v: IUPHAR/BPS Guide to Pharmacology CITE. 2019

Cannabinoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Cannabinoid Receptors [107]) are activated by endogenous ligands that include N-arachidonoylethanolamine (anandamide), N-homo-γ-linolenoylethanolamine, N-docosatetra-7,10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb66c858be90662d3865553ef0e66e9f
https://doi.org/10.2218/gtopdb/f13/2019.4

Endocannabinoid signaling at the periphery: 50 years after THC

Autor: Keith A. Sharkey, Pal Pacher, Vincenzo Di Marzo, Mauro Maccarrone, George Kunos, Raphael Mechoulam, Tamás Bíró, Sudhansu K. Dey, Itai Bab, Justin C. Konje, Guy A. Cabral, Andreas Zimmer

Publikováno v: Trends in pharmacological sciences (Regular ed., Print) 36 (2015): 277–296. doi:10.1016/j.tips.2015.02.008
info:cnr-pdr/source/autori:Maccarrone M.; Bab I.; Biro T.; Cabral G.A.; Dey S.K.; Di Marzo V.; Konje J.C.; Kunos G.; Mechoulam R.; Pacher P.; Sharkey K.A.; Zimmer A./titolo:Endocannabinoid signaling at the periphery: 50 years after THC/doi:10.1016%2Fj.tips.2015.02.008/rivista:Trends in pharmacological sciences (Regular ed., Print)/anno:2015/pagina_da:277/pagina_a:296/intervallo_pagine:277–296/volume:36

In 1964, the psychoactive ingredient of Cannabis sativa, ?9-tetrahydrocannabinol (THC), was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed endocannabinoids (eCBs), were discovered: N-arachidonoylethanolamine (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b31b6c492fed949f8c87b5804dccf00
https://doi.org/10.1016/j.tips.2015.02.008

Identification of Peptidases in Highly Pathogenic vs. Weakly PathogenicNaegleria fowleriAmebae

Autor: Ishan K. Vyas, Melissa Jamerson, Francine Marciano-Cabral, Guy A. Cabral

Publikováno v: Journal of Eukaryotic Microbiology. 62:51-59

Naegleria fowleri, a free-living ameba, is the causative agent of Primary Amebic Meningoencephalitis. Highly pathogenic mouse-passaged amebae (Mp) and weakly pathogenic axenically grown (Ax) N. fowleri were examined for peptidase activity. Zymography

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7bab43dbcd09b52d46545fcc8d57b7
https://doi.org/10.1111/jeu.12152

The 18th Annual Scientific Conference of the Society on NeuroImmune Pharmacology

Autor: Sulie L. Chang, Guy A. Cabral

Publikováno v: Journal of Neuroimmune Pharmacology. 7:1-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0bf31d98f1bf231f6f50f44d1e8a636
https://doi.org/10.1007/s11481-012-9348-1