Zobrazeno 1 - 10
of 321
pro vyhledávání: '"Guy, Pratt"'
Autor:
Vesna S. Stanulović, Shorog Al Omair, Michelle A.C. Reed, Jennie Roberts, Sandeep Potluri, Taylor Fulton-Ward, Nancy Gudgeon, Emma L. Bishop, Juliette Roels, Tracey A. Perry, Sovan Sarkar, Guy Pratt, Tom Taghon, Sarah Dimeloe, Ulrich L. Günther, Christian Ludwig, Maarten Hoogenkamp
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the immune system. Approximately 20% of paediatric and 50% of adult T-ALL patients have refractory disease or relapse and die from the disease. To improve patient outcome new therapeutics are
Externí odkaz:
https://doaj.org/article/89ee5f73be0d42d2909cf64e304355a7
Autor:
Thomas Roberts, Grace Uwenedi, Rachel Bruton, Graham McIlroy, Sarah Damery, Panagiota Sylla, Nicola Logan, Sam Scott, May Lau, Ahmed Elzaidi, Siobhan Plass, Soumyajit Mallick, Katie Spencer, Christine Stephens, Christopher Bentley, Guy Pratt, Jianmin Zuo, Shankara Paneesha, Brian Willett, Paul Moss, Helen Parry
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/461ffaf1e5f841828038eef17f6ecdf9
Autor:
Sam Keaveney, Alina Dragan, Mihaela Rata, Matthew Blackledge, Erica Scurr, Jessica M. Winfield, Joshua Shur, Dow-Mu Koh, Nuria Porta, Antonio Candito, Alexander King, Winston Rennie, Suchi Gaba, Priya Suresh, Paul Malcolm, Amy Davis, Anjumara Nilak, Aarti Shah, Sanjay Gandhi, Mauro Albrizio, Arnold Drury, Guy Pratt, Gordon Cook, Sadie Roberts, Matthew Jenner, Sarah Brown, Martin Kaiser, Christina Messiou
Publikováno v:
Insights into Imaging, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background The Myeloma Response Assessment and Diagnosis System (MY-RADS) guidelines establish a standardised acquisition and analysis pipeline for whole-body MRI (WB-MRI) in patients with myeloma. This is the first study to assess image qua
Externí odkaz:
https://doaj.org/article/6e65c366b56d454d831d89851e12e0aa
Publikováno v:
Hemato, Vol 4, Iss 2, Pp 184-195 (2023)
Renal disorders are uncommonly associated with IgM MGUS and Waldenström macroglobulinaemia (WM). Data are limited to large case series that suggest that related renal involvement occurs in 5% of patients with WM. Although uncommon, there is a much g
Externí odkaz:
https://doaj.org/article/e0b135891f90435b94f78528703b6d2e
Autor:
Jonathan Carmichael, Frances Seymour, Graham McIlroy, Sarrah Tayabali, Rosie Amerikanou, Sylvia Feyler, Rakesh Popat, Guy Pratt, Christopher Parrish, A. John Ashcroft, Graham H. Jackson, Gordon Cook
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are especially susceptible to poor outcomes. However, even for MM patients
Externí odkaz:
https://doaj.org/article/4261423c0dbc42d4ae909538097e3338
Autor:
Gordon Cook, John Ashcroft, Mariana Fernandez, Sarah Henshaw, Zeyad Khalaf, Guy Pratt, Anish Tailor, Neil Rabin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Daratumumab is a CD38-directed monoclonal antibody indicated to treat multiple myeloma (MM). Daratumumab was initially administered intravenously (IV), subsequently a subcutaneous (SC) formulation was developed to increase convenience of administrati
Externí odkaz:
https://doaj.org/article/1629f4dd41964cfe987dfede4a32426d
Autor:
Helen Parry, Graham McIlroy, Rachel Bruton, Sarah Damery, Grace Tyson, Nicola Logan, Chris Davis, Brian Willett, Jianmin Zuo, Myah Ali, Manjit Kaur, Christine Stephens, Dawn Brant, Ashley Otter, Tina McSkeane, Hayley Rolfe, Sian Faustini, Alex Richter, Sophie Lee, Farooq Wandroo, Salim Shafeek, Guy Pratt, Shankara Paneesha, Paul Moss
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background Immune suppression is a clinical feature of chronic lymphocytic leukaemia (CLL), and patients show increased vulnerability to SARS-CoV-2 infection and suboptimal antibody responses. Method We studied antibody responses in 500 pati
Externí odkaz:
https://doaj.org/article/0b63fc659fe944b690bb8d6c08a4eb4d
Autor:
Roger Owen, Mark Cook, David Meads, David A Cairns, Christopher Parrish, Gordon Cook, Kwee Yong, Guy Pratt, Martin Kaiser, Karthik Ramasamy, Graham Jackson, Catherine Olivier, Amy Beth Coulson, Kara-Louise Royle, Anna Hockaday, Ruth de Tute, Bryony Dawkins, Mark Drayson, Jonathan Sive, Holger W Auner, Sergio Quezada, Lorna Barnard, Rhiannon Lambkin, Andrea Paterson, Mike Chapman, Rakesh Popat, Ceri Bygrave, Andrew Chantry, Samir Asher
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Multiple myeloma is a plasma cell malignancy that accounts for 1%–2% of newly diagnosed cancers.At diagnosis, approximately 20% of patients can be identified, using cytogenetics, to have inferior survival (high-risk). Additionally, sta
Externí odkaz:
https://doaj.org/article/bf5f5424894a43a2927ade7759c778ff
Autor:
Stella Bowcock, Catherine Atkin, Gulnaz Iqbal, Guy Pratt, Kwee Yong, Richard D. Neal, Tim Planche, Kamaraj Karunanithi, Stephen Jenkins, Simon Stern, Sarah Arnott, Peter Toth, Farooq Wandroo, Janet Dunn, Mark T. Drayson
Publikováno v:
Cancers, Vol 15, Iss 13, p 3337 (2023)
Multiple myeloma (MM) patients risk diagnostic delays and irreversible organ damage. In those with newly diagnosed myeloma, we explored the presenting symptoms to identify early signals of MM and their relationships to organ damage. The symptoms were
Externí odkaz:
https://doaj.org/article/999c5dc57d5549b7afc7228c88afec25
Autor:
Suliman A. Alsagaby, Ian A. Brewis, Rajendran Vijayakumar, Fahad A. Alhumaydhi, Ameen S. Alwashmi, Naif K. Alharbi, Waleed Al Abdulmonem, Mariappan Premanathan, Guy Pratt, Christopher Fegan, Christopher Pepper, Paul Brennan
Publikováno v:
Electronic Journal of Biotechnology, Vol 52, Iss , Pp 1-12 (2021)
Background: Chronic lymphocytic leukaemia (CLL) is a neoplasm of B-cells characterized by variable prognosis. Exploring the proteome of CLL cells may provide insights into the disease. Therefore, eleven proteomics experiments were conducted on eleven
Externí odkaz:
https://doaj.org/article/f6eb4d1dc0b34907abe889cfbb7a1fd5