Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Guy, Caljon"'
Autor:
Federica Carnamucio, Claudia Foti, Nicola Micale, Natascha Van Pelt, An Matheeussen, Guy Caljon, Ottavia Giuffrè
Publikováno v:
ACS Omega, Vol 9, Iss 26, Pp 29000-29008 (2024)
Externí odkaz:
https://doaj.org/article/6fd08d4b26d7472d94771e7d4fcca744
Autor:
Brian W. Slafer, Marco A. Dessoy, Ramon G. de Oliveira, Maria C. Mollo, Eun Lee, An Matheeussen, Louis Maes, Guy Caljon, Leonardo L. G. Ferreira, Renata Krogh, Adriano D. Andricopulo, Luiza R. Cruz, Charles E. Mowbray, Jadel M. Kratz, Luiz C. Dias
Publikováno v:
ACS Omega, Vol 9, Iss 20, Pp 22360-22370 (2024)
Externí odkaz:
https://doaj.org/article/181f8460774544aa8d922443939c65c7
Autor:
Cassandra Present, Roberson Donola Girão, Cai Lin, Guy Caljon, Serge Van Calenbergh, Otacilio Moreira, Leonardo Alexandre de Souza Ruivo, Marcos Meuser Batista, Raquel Azevedo, Denise da Gama Jaen Batista, Maria de Nazaré Correia Soeiro
Publikováno v:
Parasitology, Vol 151, Pp 506-513 (2024)
Leishmania is a trypanosomatid parasite that causes skin lesions in its cutaneous form. Current therapies rely on old and expensive drugs, against which the parasites have acquired considerable resistance. Trypanosomatids are unable to synthesize pur
Externí odkaz:
https://doaj.org/article/fdbc09b2ce2b46c1a1ac11bb0c9763fd
Autor:
Benoit Stijlemans, Patrick De Baetselier, Inge Van Molle, Laurence Lecordier, Erika Hendrickx, Ema Romão, Cécile Vincke, Wendy Baetens, Steve Schoonooghe, Gholamreza Hassanzadeh-Ghassabeh, Hannelie Korf, Marie Wallays, Joar E. Pinto Torres, David Perez-Morga, Lea Brys, Oscar Campetella, María S. Leguizamón, Mathieu Claes, Sarah Hendrickx, Dorien Mabille, Guy Caljon, Han Remaut, Kim Roelants, Stefan Magez, Jo A. Van Ginderachter, Carl De Trez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Human African trypanosomiasis or sleeping sickness, caused by the protozoan parasite Trypanosoma brucei, is characterized by the manipulation of the host’s immune response to ensure parasite invasion and persistence. Uncovering key molecul
Externí odkaz:
https://doaj.org/article/246f0d22755a498bb72fe9a96e853695
Autor:
Laura Dirkx, Sara I Van Acker, Yasmine Nicolaes, João Luís Reis Cunha, Rokaya Ahmad, Rik Hendrickx, Ben Caljon, Hideo Imamura, Didier G Ebo, Daniel C Jeffares, Yann G-J Sterckx, Louis Maes, Sarah Hendrickx, Guy Caljon
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012181 (2024)
Addressing the challenges of quiescence and post-treatment relapse is of utmost importance in the microbiology field. This study shows that Leishmania infantum and L. donovani parasites rapidly enter into quiescence after an estimated 2-3 divisions i
Externí odkaz:
https://doaj.org/article/c3328a026fb045d3b54dc41a434fc149
Autor:
Lalita Roy, Kristien Cloots, Surendra Uranw, Keshav Rai, Narayan R. Bhattarai, Tom Smekens, Rik Hendrickx, Guy Caljon, Epco Hasker, Murari L. Das, Wim Van Bortel
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract Background Visceral leishmaniasis (VL), a life-threatening neglected tropical disease, is targeted for elimination from Nepal by the year 2026. The national VL elimination program is still confronted with many challenges including the increa
Externí odkaz:
https://doaj.org/article/e5a34f5dfdb847eea910318fad614106
Autor:
Jean-Gonfi Mvondo Mbala, Dani Thierry Mawete, Alain Nanikafuako Makiese, Prosper Lwanzo Kwiraviwe, Bibiche Kuyubuka Pangu, Eric Buini Nguimi, Richard Cimanga Kanyanga, Luc Pieters, Gilles Degotte, Michel Frederich, Aristote Matondo, Natascha Van Pelt, Guy Caljon, Bernard Pirotte, Blaise Mbala Mavinga, Sylvie-Mireille Bambi-Nyanguile
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101284- (2024)
After establishment of the pharmacokinetic and toxicological profile of quinine derivatives using in silico approaches, this study reports the synthesis of new acetyl and benzoyl esters of quinine bearing one or more fluorine or chlorine atoms on the
Externí odkaz:
https://doaj.org/article/a559aa89d2134a43a59855d9369fe10d
Autor:
Milan S. G. Keirsebelik, Mariana R. David, Márcio Galvão Pavan, Dinair Couto-Lima, Miriam Palomino, Rafi Ur Rahman, Ary A. Hoffmann, Ana C. Bahia, Guy Caljon, Rafael Maciel-de-Freitas
Publikováno v:
Insects, Vol 15, Iss 6, p 393 (2024)
The mosquito Aedes aegypti is distributed worldwide and is recognized as the primary vector for dengue in numerous countries. To investigate whether the fitness cost of a single DENV-1 isolate varies among populations, we selected four Ae. aegypti po
Externí odkaz:
https://doaj.org/article/b2092165b3e2426c9bea56459777d257
Autor:
Dorien Mabille, Laura Dirkx, Sofie Thys, Marjorie Vermeersch, Daniel Montenye, Matthias Govaerts, Sarah Hendrickx, Peter Takac, Johan Van Weyenbergh, Isabel Pintelon, Peter Delputte, Louis Maes, David Pérez-Morga, Jean-Pierre Timmermans, Guy Caljon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
A number of human African trypanosomiasis, or sleeping sickness, patients suffer from respiratory symptoms commonly attributed to cardiac insufficiency. Here, the authors characterise the role of pulmonary Trypanosoma brucei in respiratory infection.
Externí odkaz:
https://doaj.org/article/e94ea4949fe04471983657287813b459
Autor:
Yang Zheng, Joachim Müller, Stefan Kunz, Marco Siderius, Louis Maes, Guy Caljon, Norbert Müller, Andrew Hemphill, Geert Jan Sterk, Rob Leurs
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 19, Iss , Pp 47-55 (2022)
As there is a continuous need for novel anti-infectives, the present study aimed to fuse two modes of action into a novel 3-nitroimidazo[1,2-b]pyridazine scaffold to improve antiparasitic efficacy. For this purpose, we combined known structural eleme
Externí odkaz:
https://doaj.org/article/71ceaef05ad240feb9f42da5d282b02b