Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Gutierrez-Achury J"'
Autor:
Deelen, P., Menelaou, A., van Leeuwen, E., Kanterakis, A., van Dijk, F., Medina-Gomez, C., Francioli, L., Hottenga, J., Karssen, L., Estrada, K., Kreiner-Møller, E., Rivadeneira, F., van Setten, J., Gutierrez-Achury, J., Westra, H., Franke, L., van Enckevort, D., Dijkstra, M., Byelas, H., van Duijn, C., including authors, Stoneking, M., https://orcid.org/0000-0001-9044-6679, Li, M., others, de Bakker, P., Wijmenga, C., Swertz, M.
Publikováno v:
European Journal of Human Genetics
European Journal of Human Genetics, 22(11), 1321-1326. Nature Publishing Group
Deelen, P, Menelaou, A, van Leeuwen, E M, Kanterakis, A, Dijk, F, Medina-Gomez, C, Francioli, L C, Hottenga, J J, Karssen, L C, Estrada, K, Kreiner-Møller, E, Rivadeneira, F, van Setten, J, Gutierrez-Achury, J, Westra, H J, Franke, L, van Enckevort, D, Dijkstra, M, Byelas, H, van Duijn, C M, Bakker, P I W, Wijmenga, C & Swertz, M 2014, ' Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands' ', European Journal of Human Genetics, vol. 22, no. 11, pp. 1321-1326 . https://doi.org/10.1038/ejhg.2014.19
European Journal of Human Genetics, 22(11), 1321-1326
European journal of human genetics, 22(11), 1321-1326. Nature Publishing Group
European Journal of Human Genetics, 22(11), 1321-1326. Nature Publishing Group
Deelen, P, Menelaou, A, van Leeuwen, E M, Kanterakis, A, Dijk, F, Medina-Gomez, C, Francioli, L C, Hottenga, J J, Karssen, L C, Estrada, K, Kreiner-Møller, E, Rivadeneira, F, van Setten, J, Gutierrez-Achury, J, Westra, H J, Franke, L, van Enckevort, D, Dijkstra, M, Byelas, H, van Duijn, C M, Bakker, P I W, Wijmenga, C & Swertz, M 2014, ' Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands' ', European Journal of Human Genetics, vol. 22, no. 11, pp. 1321-1326 . https://doi.org/10.1038/ejhg.2014.19
European Journal of Human Genetics, 22(11), 1321-1326
European journal of human genetics, 22(11), 1321-1326. Nature Publishing Group
Although genome-wide association studies (GWAS) have identified many common variants associated with complex traits, low-frequency and rare variants have not been interrogated in a comprehensive manner. Imputation from dense reference panels, such as
Autor:
De Lange, KM, Moutsianas, L, Lee, JC, Lamb, CA, Luo, Y, Kennedy, NA, Jostins, L, Rice, DL, Gutierrez-Achury, J, Ji, S-G, Heap, G, Nimmo, ER, Edwards, C, Henderson, P, Mowat, C, Sanderson, J, Satsangi, J, Simmons, A, Wilson, DC, Tremelling, M, Hart, A, Mathew, CG, Newman, WG, Parkes, M, Lees, CW, Uhlig, H, Hawkey, C, Prescott, NJ, Ahmad, T, Mansfield, JC, Anderson, CA, Barrett, JC
Genetic association studies have identified 215 risk loci for inflammatory bowel disease, thereby uncovering fundamental aspects of its molecular biology. We performed a genome-wide association study of 25,305 individuals and conducted a meta-analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc5647dd9b1c25851c7aa77c79499a35
Autor:
Gutierrez-Achury, J., Romanos, J., Bakker, S.F., Kumar, V., Haas, E.C. de, Trynka, G., Ricano-Ponce, I., Steck, A., Chen, W.M., Onengut-Gumuscu, S., Simsek, S., Rewers, M., Mulder, C.J., Liu, E., Rich, S.S., Wijmenga, C., Type 1 Diabet Genetics Consortium
Publikováno v:
Gutierrez-Achury, J, Romanos, J, Bakker, S F, Kumar, V, de Haas, E C, Trynka, G, Ricano-Ponce, I, Steck, A, Chen, W M, Onengut-Gumuscu, S, Simsek, S, Rewers, M, Mulder, C J, Liu, E, Rich, S S & Wijmenga, C 2015, ' Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity ', Diabetes Care, vol. 38, pp. S37-S44 . https://doi.org/10.2337/dcs15-2007
Diabetes Care
Diabetes Care, 38, S37-S44
Diabetes Care, 38, S37-S44. AMER DIABETES ASSOC
Diabetes Care, 38, S37-S44. American Diabetes Association Inc.
Diabetes Care
Diabetes Care, 38, S37-S44
Diabetes Care, 38, S37-S44. AMER DIABETES ASSOC
Diabetes Care, 38, S37-S44. American Diabetes Association Inc.
Type 1 diabetes (T1D) and celiac disease (CeD) cluster in families and can occur in the same individual. Genetic loci have been associated with susceptibility to both diseases. Our aim was to explore the genetic differences between individuals develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985f868978241bb4d540105cdd7ab58d
https://hdl.handle.net/1887/101077
https://hdl.handle.net/1887/101077
Autor:
Romanos, J., Rosén, A., Kumar, V., Trynka, G., Franke, L., Szperl, A., Gutierrez-Achury, J., van Diemen, C.C., Kanninga, R., Jankipersadsing, S.A., Steck, A., Eisenbarth, G., van Heel, D.A., Cukrowska, B., Bruno, V., Mazzilli, M.C., Núñez, C., Bilbao, J.R., Mearin, M.L., Barisani, D., Rewers, M., Norris, J.M., Ivarsson, A., Boezen. H.M., Liu, E., Wijmenga, C., Prevent, C.D., Kolaček, Sanja, Steck, A, Mearin, M, L, Barisani, D, Rewers, M, Boezen, H.M.
Publikováno v:
Gut
Gut, 63(3), 415-422
Europe PubMed Central
Gut, 63(3), 415-422. BMJ PUBLISHING GROUP
Gut, 63(3), 415-422
Europe PubMed Central
Gut, 63(3), 415-422. BMJ PUBLISHING GROUP
Background The majority of coeliac disease (CD) patients are not being properly diagnosed and therefore remain untreated, leading to a greater risk of developing CD-associated complications. The major genetic risk heterodimer, HLA-DQ2 and DQ8, is alr
Autor:
Stahl, E. A., Wegmann, D., Trynka, G., Gutierrez Achury, J., Do, R., Voight, B. F., Kraft, P., Chen, R., Kallberg, H. J., F. A. S., Replication, D. G., Consortium, M. a., Genetics, M. I., Kathiresan, S., Wijmenga, C., Gregersen, P. K., Alfredsson, L., Siminovitch, K. A., Worthington, J., P. I. W., Raychaudhuri, S., Plenge, R. M., Voight, Bf, Scott, Lj, Steinthorsdottir, V, Morris, Ap, Dina, C, Welch, Rp, Zeggini, E, Huth, C, Aulchenko, Ys, Thorleifsson, G, Mcculloch, Lj, Ferreira, T, Grallert, H, Amin, N, Wu, G, Willer, Cj, Raychaudhuri, S, Mccarroll, Sa, Langenberg, C, Hofmann, Om, Dupuis, J, Qi, L, Segrè, Av, van Hoek, M, Navarro, P, Ardlie, K, Balkau, B, Benediktsson, R, Bennett, Aj, Blagieva, R, Boerwinkle, E, Bonnycastle, Ll, Boström, Kb, Bravenboer, B, Bumpstead, S, Burtt, Np, Charpentier, G, Chines, Ps, Cornelis, M, Couper, Dj, Crawford, G, Doney, As, Elliott, Ks, Elliott, Al, Erdos, Mr, Fox, Cs, Franklin, Cs, Ganser, M, Gieger, C, Grarup, N, Green, T, Griffin, S, Groves, Cj, Guiducci, C, Hadjadj, S, Hassanali, N, Herder, C, Isomaa, B, Jackson, Au, Johnson, Pr, Jørgensen, T, Kao, Wh, Klopp, N, Kong, A, Kraft, P, Kuusisto, J, Lauritzen, T, Li, M, Lieverse, A, Lindgren, Cm, Lyssenko, V, Marre, M, Meitinger, T, Midthjell, K, Morken, Ma, Narisu, N, Nilsson, P, Owen, Kr, Payne, F, Perry, Jr, Petersen, Ak, Platou, C, Proença, C, Prokopenko, I, Rathmann, W, Rayner, Nw, Robertson, Nr, Rocheleau, G, Roden, M, Sampson, Mj, Saxena, R, Shields, Bm, Shrader, P, Sigurdsson, G, Sparsø, T, Strassburger, K, Stringham, Hm, Sun, Q, Swift, Aj, Thorand, B, Tichet, J, Tuomi, T, van Dam RM, van Haeften TW, van Herpt, T, van Vliet Ostaptchouk JV, Walters, Gb, Weedon, Mn, Wijmenga, C, Witteman, J, Bergman, Rn, Cauchi, S, Collins, Fs, Gloyn, Al, Gyllensten, U, Hansen, T, Hide, Wa, Hitman, Ga, Hofman, A, Hunter, Dj, Hveem, K, Laakso, M, Mohlke, Kl, Morris, Ad, Palmer, Cn, Pramstaller, Pp, Rudan, I, Sijbrands, E, Stein, Ld, Tuomilehto, J, Uitterlinden, A, Walker, M, Wareham, Nj, Watanabe, Rm, Abecasis, Gr, Boehm, Bo, Campbell, H, Daly, Mj, Hattersley, At, Hu, Fb, Meigs, Jb, Pankow, Js, Pedersen, O, Wichmann, He, Barroso, I, Florez, Jc, Frayling, Tm, Groop, L, Sladek, R, Thorsteinsdottir, U, Wilson, Jf, Illig, T, Froguel, P, van Duijn CM, Stefansson, K, Altshuler, D, Boehnke, M, Mccarthy, Mi, Kathiresan, S, Williams, G, Nathan, Dm, Macrae, Ca, O'Donnell, Cj, Ardissino, D, Merlini, Pa, Berzuini, C, Bernardinelli, L, Peyvandi, F, Tubaro, M, Celli, P, Ferrario, M, Fetiveau, R, Marziliano, N, Casari, G, Galli, M, Ribichini, Flavio Luciano, Rossi, M, Bernardi, F, Zonzin, P, Piazza, A, Mannucci, Pm, Schwartz, Sm, Siscovick, Ds, Yee, J, Friedlander, Y, Elosua, R, Marrugat, J, Lucas, G, Subirana, I, Sala, J, Ramos, R, Salomaa, V, Havulinna, As, Peltonen, L, Melander, O, Berglund, G, Hirschhorn, Jn, Asselta, R, Duga, S, Spreafico, M, Musunuru, K, Purcell, S, Surti, A, Gianniny, L, Mirel, D, Parkin, M, Burtt, N, Gabriel, Sb
Publikováno v:
Nature Genetics, 44(5), 483-+. Nature Publishing Group
The genetic architectures of common, complex diseases are largely uncharacterized. We modeled the genetic architecture underlying genome-wide association study (GWAS) data for rheumatoid arthritis and developed a new method using polygenic risk-score
Publikováno v:
Journal of Internal Medicine, 269(6), 591-603. Wiley
Gutierrez-Achury J, Coutinho de Almeida R, Wijmenga C (University Medical Centre Groningen and University of Groningen, Groningen, the Netherlands; University of Brasilia School of Health Sciences, Brasilia, DF, Brazil). Shared genetics in coeliac di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::fd28f54e9b083ce66eb651ae537989a1
https://research.rug.nl/en/publications/3a61d56e-90f0-499b-ab95-8ddb6c3e52ea
https://research.rug.nl/en/publications/3a61d56e-90f0-499b-ab95-8ddb6c3e52ea
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.