Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin–angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial

Autor: Ackland, Gareth, Martin, Tim, Fernandez, Maria, Seidu, Fatima, Pakats, Mari-Liis, Mahr, Otto, MacDonald, Neil, Santos, Filipa Dos, Garcia, Amaia Arrieta, Uddin, Ruzena, Begum, Salma, Pearse, Rupert, Subhedar, Emily, Wan, Yize, Patel, Akshaykumar, Shahid, Tasnin, Gooneratne, Mevan, Trainer, Charlotte, Griffiths, Bethan, Dunkley, Steven, May, Shaun, Walker, Sophie, Fowler, Alexander, Stephens, Timothy, Oliveira, Monica, Januszewska, Marta, Niebrzegowska, Edyta, Amaral, Vanessa, Kassam, Jamila, Young, Sophie, Ahmad, Shanaz, Whalley, Jan, Haines, Ryan, Hui, Sara, Hammond, Rob, Crane, David, Brealey, David, Bampoe, Sohail, Stephens, Robert, Reyes, Anna, Martir, Gladys, Diaz, Chimverly, Cleland, Stuart, Minto, Gary, Wilmshurst, Natasha, Affleck, Debbie-Claire, Ward, Tracy, Werrett, Gavin, Cummins, Susan, Amber, Alan, Biffen, Andrew, Boumphrey, Stephen, Cann, Elizabeth, Eglinton, Charlotte, Jones, Elaine, Mwadeyi, Memory, Piesley, Sam, Cowan, Richard, Alderton, Julie, Reed, Fiona, Smith, Joanne, Turner, Amy, Madziva, Lorraine, Patrick, Abigail, Harris, Penny, Lang, Harry, Middleditch, Alexander, Pickering, Anthony, O’Donovan, Catherine, Houlihan, Rebecca, Jarvis, Rosina, Shrimpton, Andrew, Farmery, Toni, Tucker, Katy, Davis, Danielle, Somanth, Sameer, Duncan, Louise, Melsom, Helen, Clark, Sarah, Kent, Melanie, Wood, Michelle, Laidlaw, Ami, Matheson-Smith, Tracy, Potts, Kathryn, Kay, Andrea, Hobson, Stefanie, Sear, John, Kapil, Vikas, Archbold, Andrew, Wilson, Matt, Dndrejaj, Drilona, Ly, Dennis, Gutierrez del Arroyo, Ana, Abbott, Tom E.F., Dias, Priyanthi, Somanath, Sameer, Pearse, Rupert M., Ackland, Gareth L.

Publikováno v: In British Journal of Anaesthesia May 2024 132(5):857-866

Human neutrophils communicate remotely via calcium-dependent glutamate-induced glutamate release

Autor: Olga Kopach, Sergyi Sylantyev, Lucie Bard, Piotr Michaluk, Janosch P. Heller, Ana Gutierrez del Arroyo, Gareth L. Ackland, Alexander V. Gourine, Dmitri A. Rusakov

Publikováno v: iScience, Vol 26, Iss 7, Pp 107236- (2023)

Summary: Neutrophils are white blood cells that are critical to acute inflammatory and adaptive immune responses. Their swarming-pattern behavior is controlled by multiple cellular cascades involving calcium-dependent release of various signaling mol

Externí odkaz: https://doaj.org/article/e29399bbfa284d4aac50d5a7106fd7e9

Interleukin-1 receptor antagonist, mode of analgesia and risk of Caesarean delivery after onset of labour: a Mendelian randomisation analysis

Autor: Ali, Amaan, Wikner, Matt, Noblett, James, Usman, Nusrat, Wray, Sarah, Blake, Holly, del Arroyo, Ana G., Abbott, Tom E.F., Weber, Valentin, Papoutsos, Constantinos, Black, Rebecca, Bruce-Hickman, Kara, Verma, Parvesh, Sadler, Chris, Barrett, Alice, Fulton, Laura, Martin, Tim, Tanqueray, Tabitha, Longbottom, Rebecca, Cancili, Lisa, Nokes, India, Frowd, Rachel, Kennedy, Natasha, Wilson, Matt, Wilson, Vicki, David, Anna L., Weist, Sarah, Newth, Olivia, Folorunsho, Morenike, Ali, Jihana, Achaempong, Yaa, Bourke, Miriam, Brunnen, Derek, Kim, Jennifer, Mak, Kei, Odor, Pete, Sarmiento, Laura, Ciechanowicz, Sarah, Ackland, Gareth L., Van Duijvenboden, Stefan, Gutierrez del Arroyo, Ana, Wilson, Matthew J.

Publikováno v: In British Journal of Anaesthesia January 2022 128(1):89-97

Adenosine signalling to astrocytes coordinates brain metabolism and function.

Autor: Theparambil, Shefeeq M., Kopach, Olga, Braga, Alice, Nizari, Shereen, Hosford, Patrick S., Sagi-Kiss, Virag, Hadjihambi, Anna, Konstantinou, Christos, Esteras, Noemi, Gutierrez Del Arroyo, Ana, Ackland, Gareth L., Teschemacher, Anja G., Dale, Nicholas, Eckle, Tobias, Andrikopoulos, Petros, Rusakov, Dmitri A., Kasparov, Sergey, Gourine, Alexander V.

Publikováno v: Nature; Aug2024, Vol. 632 Issue 8023, p139-146, 8p

Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study

Autor: Cuthbertson, B.H., Wijeysundera, D.N., Pearse, R.M., Myles, P.S., Abbott, T.E.F., Shulman, M.A., Torres, E., Ambosta, A., Melo, M., Mamdani, M., Thorpe, K.E., Wallace, S., Farrington, C., Croal, B.L., Grocott, M.P.W., Granton, J.T., Oh, P., Thompson, B., Levett, D., Hillis, G., Beattie, W.S., Wijeysundera, H.C., Wijeysundera, Duminda N., Beattie, W. Scott, Hillis, Graham S., Abbott, Tom E.F., Shulman, Mark A., Ackland, Gareth L., Mazer, C. David, Myles, Paul S., Pearse, Rupert M., Cuthbertson, Brian H., Ellis, M., Borg, B., Kerridge, R.K., Douglas, J., Brannan, J., Pretto, J., Godsall, M.G., Beauchamp, N., Allen, S., Kennedy, A., Wright, E., Malherbe, J., Ismail, H., Riedel, B., Melville, A., Sivakumar, H., Murmane, A., Kenchington, K., Kirabiyik, Y., Gurunathan, U., Stonell, C., Brunello, K., Steele, K., Tronstad, O., Masel, P., Dent, A., Smith, E., Bodger, A., Abolfathi, M., Sivalingam, P., Hall, A., Painter, T.W., Macklin, S., Elliott, A., Carrera, A.M., Terblanche, N.C.S., Pitt, S., Samuels, J., Wilde, C., Leslie, K., MacCormick, A., Bramley, D., Southcott, A.M., Grant, J., Taylor, H., Bates, S., Towns, M., Tippett, A., Marshall, F., Mazer, C.D., Kunasingam, J., Yagnik, A., Crescini, C., Yagnik, S., McCartney, C.J.L., Choi, S., Somascanthan, P., Flores, K., Karkouti, K., Clarke, H.A., Jerath, A., McCluskey, S.A., Wasowicz, M., Day, L., Pazmino-Canizares, J., Belliard, R., Lee, L., Dobson, K., Chan, V., Brull, R., Ami, N., Stanbrook, M., Hagen, K., Campbell, D., Short, T., Van Der Westhuizen, J., Higgie, K., Lindsay, H., Jang, R., Wong, C., Mcallister, D., Ali, M., Kumar, J., Waymouth, E., Kim, C., Dimech, J., Lorimer, M., Tai, J., Miller, R., Sara, R., Collingwood, A., Olliff, S., Gabriel, S., Houston, H., Dalley, P., Hurford, S., Hunt, A., Andrews, L., Navarra, L., Jason-Smith, A., Thompson, H., McMillan, N., Back, G., Lum, M., Martin, D., James, S., Filipe, H., Pinto, M., Kynaston, S., Phull, M., Beilstein, C., Bodger, P., Everingham, K., Hu, Y., Niebrzegowska, E., Corriea, C., Creary, T., Januszewska, M., Ahmad, T., Whalley, J., Haslop, R., McNeil, J., Brown, A., MacDonald, N., Pakats, M., Greaves, K., Jhanji, S., Raobaikady, R., Black, E., Rooms, M., Lawrence, H., Koutra, M., Pirie, K., Gertsman, M., Jack, S., Celinski, M., Edwards, M., Salmon, K., Bolger, C., Loughney, L., Seaward, L., Collins, H., Tyrell, B., Tantony, N., Golder, K., Ackland, G.L., Stephens, R.C.M., Gallego-Paredes, L., Reyes, A., Gutierrez del Arroyo, A., Raj, A., Lifford, R.

Publikováno v: In British Journal of Anaesthesia March 2020 124(3):261-270