Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Guthrie ML"'
Autor:
McMurray, KMJ, Ramaker, MJ, Barkley-Levenson, AM, Sidhu, PS, Elkin, PK, Reddy, MK, Guthrie, ML, Cook, JM, Rawal, VH, Arnold, LA, Dulawa, SC, Palmer, AA
Publikováno v:
Molecular psychiatry, vol 23, iss 2
McMurray, KMJ; Ramaker, MJ; Barkley-Levenson, AM; Sidhu, PS; Elkin, PK; Reddy, MK; et al.(2018). Identification of a novel, fast-acting GABAergic antidepressant. MOLECULAR PSYCHIATRY, 23(2), 384-391. doi: 10.1038/mp.2017.14. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9x4284kb
McMurray, KMJ; Ramaker, MJ; Barkley-Levenson, AM; Sidhu, PS; Elkin, PK; Reddy, MK; et al.(2018). Identification of a novel, fast-acting GABAergic antidepressant. MOLECULAR PSYCHIATRY, 23(2), 384-391. doi: 10.1038/mp.2017.14. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9x4284kb
Current pharmacotherapies for depression exhibit slow onset, side effects and limited efficacy. Therefore, identification of novel fast-onset antidepressants is desirable. GLO1 is a ubiquitous cellular enzyme responsible for the detoxification of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::01d7ea718980a4d27ad304f6b3b33c99
https://escholarship.org/uc/item/9x4284kb
https://escholarship.org/uc/item/9x4284kb
Autor:
Lador A; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Peterson LE; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Swarup V; Arizona Heart Rhythm Center, Phoenix, Arizona., Schurmann PA; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas; Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas., Makkar A; Arizona Heart Rhythm Center, Phoenix, Arizona., Doshi RN; Division of Cardiology, Keck-USC University Hospital, University of Southern California, Los Angeles, California., DeLurgio D; Division of Cardiology, Emory St. Joseph's Hospital, Emory University, Atlanta, Georgia., Athill CA; San Diego Cardiac Center, Sharp Memorial Hospital, San Diego, California., Ellenbogen KA; Division of Cardiology, Virginia Commonwealth University School of Medicine, Richmond, Virginia., Natale A; Texas Cardiac Arrhythmia Institute, St David's Medical Center, Austin, Texas., Koneru J; Division of Cardiology, Virginia Commonwealth University School of Medicine, Richmond, Virginia., Dave AS; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Giorgberidze I; Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas., Afshar H; Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas., Guthrie ML; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Bunge R; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Morillo CA; Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada., Kleiman NS; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Valderrábano M; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas. Electronic address: MValderrabano@houstonmethodist.org.
Publikováno v:
Heart rhythm [Heart Rhythm] 2021 Jul; Vol. 18 (7), pp. 1045-1054. Date of Electronic Publication: 2021 Jan 19.
Autor:
Roni MSR; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States., Zahn NM; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States., Mikulsky BN; Pantherics Incorporated, La Jolla, California 92037, United States., Webb DA; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States., Mian MY; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States., Knutson DE; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States., Guthrie ML; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States., Cook JM; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States., Stafford DC; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States | Pantherics Incorporated, La Jolla, California 92037, United States., Arnold LA; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, United States | Pantherics Incorporated, La Jolla, California 92037, United States.
Publikováno v:
Current drug metabolism [Curr Drug Metab] 2021; Vol. 22 (14), pp. 1114-1123.
Autor:
Valderrábano M; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Peterson LE; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Swarup V; Arizona Heart Rhythm Center, Phoenix., Schurmann PA; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas.; Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas., Makkar A; Arizona Heart Rhythm Center, Phoenix., Doshi RN; Keck-USC University Hospital, University of Southern California, Los Angeles., DeLurgio D; Emory St Joseph's Hospital, Emory University, Atlanta, Georgia., Athill CA; Sharp Memorial Hospital, San Diego, California., Ellenbogen KA; Virginia Commonwealth University School of Medicine, Richmond., Natale A; Texas Cardiac Arrhythmia Institute, St David's Medical Center, Austin., Koneru J; Virginia Commonwealth University School of Medicine, Richmond., Dave AS; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Giorgberidze I; Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas., Afshar H; Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas., Guthrie ML; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Bunge R; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas., Morillo CA; Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada., Kleiman NS; Houston Methodist DeBakey Heart and Vascular Center and Research Institute, Houston, Texas.
Publikováno v:
JAMA [JAMA] 2020 Oct 27; Vol. 324 (16), pp. 1620-1628.
Autor:
Forkuo GS, Nieman AN, Kodali R, Zahn NM, Li G, Roni MSR, Stephen MR, Harris TW, Jahan R, Guthrie ML, Yu OB, Fisher JL, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA
Publikováno v:
Molecular pharmaceutics [Mol Pharm] 2019 Nov 04; Vol. 16 (11), pp. 4756. Date of Electronic Publication: 2019 Oct 21.
Autor:
Forkuo GS; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Nieman AN; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Kodali R; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Zahn NM; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Li G; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Rashid Roni MS; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Stephen MR; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Harris TW; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Jahan R; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Guthrie ML; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Yu OB; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Fisher JL; Department of Pharmacology, Physiology & Neuroscience , University of South Carolina School of Medicine , Columbia , South Carolina 29208 , United States., Yocum GT; Department of Anesthesiology , Columbia University , New York , New York 10032 , United States., Emala CW; Department of Anesthesiology , Columbia University , New York , New York 10032 , United States., Steeber DA; Department of Biological Sciences , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Stafford DC; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Cook JM; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States., Arnold LA; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States.
Publikováno v:
Molecular pharmaceutics [Mol Pharm] 2018 May 07; Vol. 15 (5), pp. 1766-1777. Date of Electronic Publication: 2018 Apr 02.
Autor:
McMurray KMJ; Committee on Neurobiology, University of Chicago, Chicago, IL, USA.; Department of Human Genetics, University of Chicago, Chicago, IL, USA., Ramaker MJ; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA., Barkley-Levenson AM; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Sidhu PS; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Elkin PK; Department of Chemistry, University of Chicago, Chicago, IL, USA., Reddy MK; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Guthrie ML; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Cook JM; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Rawal VH; Department of Chemistry, University of Chicago, Chicago, IL, USA., Arnold LA; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Dulawa SC; Committee on Neurobiology, University of Chicago, Chicago, IL, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Palmer AA; Department of Human Genetics, University of Chicago, Chicago, IL, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.
Publikováno v:
Molecular psychiatry [Mol Psychiatry] 2018 Feb; Vol. 23 (2), pp. 384-391. Date of Electronic Publication: 2017 Mar 21.
Autor:
Forkuo GS; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Nieman AN; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Yuan NY; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Kodali R; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Yu OB; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Zahn NM; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Jahan R; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Li G; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Stephen MR; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Guthrie ML; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Poe MM; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Hartzler BD; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Harris TW; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Yocum GT; Department of Anesthesiology, Columbia University , New York, New York 10032, United States., Emala CW; Department of Anesthesiology, Columbia University , New York, New York 10032, United States., Steeber DA; Department of Biological Sciences, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Stafford DC; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Cook JM; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States., Arnold LA; Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin 53201, United States.
Publikováno v:
Molecular pharmaceutics [Mol Pharm] 2017 Jun 05; Vol. 14 (6), pp. 2088-2098. Date of Electronic Publication: 2017 May 01.
Autor:
Jahan R; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Stephen MR; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Forkuo GS; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Kodali R; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Guthrie ML; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Nieman AN; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Yuan NY; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Zahn NM; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Poe MM; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Li G; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Yu OB; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Yocum GT; Department of Anesthesiology, Columbia University, New York, NY, 10032, United States., Emala CW; Department of Anesthesiology, Columbia University, New York, NY, 10032, United States., Stafford DC; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States., Cook JM; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States. Electronic address: capncook@uwm.edu., Arnold LA; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI, 53211, United States. Electronic address: arnold2@uwm.edu.
Publikováno v:
European journal of medicinal chemistry [Eur J Med Chem] 2017 Jan 27; Vol. 126, pp. 550-560. Date of Electronic Publication: 2016 Nov 24.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.