Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Gutcaits, A."'
Publikováno v:
Latvian Journal of Physics & Technical Sciences; 2023 Supplement 6, Vol. 60 Issue 6, p124-141, 18p
Autor:
Rummel, Andreas, Eichner, Timo, Weil, Tanja, Karnath, Tino, Gutcaits, Aleksandrs, Mahrhold, Stefan, Sandhoff, Konrad, Proia, Richard L., Acharya, K. Ravi, Bigalke, Hans, Binz, Thomas
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2007 Jan 01. 104(1), 359-364.
Externí odkaz:
https://www.jstor.org/stable/25426102
Autor:
Gutcaits Aleksandrs, Gupta Pawan
Publikováno v:
Letters in Drug Design & Discovery. 16:11-20
Background: B-cell Lymphoma Extra Large (Bcl-XL) belongs to B-cell Lymphoma two (Bcl-2) family. Due to its over-expression and anti-apoptotic role in many cancers, it has been proven to be a more biologically relevant therapeutic target in anti-cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeadb4a1dcbfaa6f896438707117230b
https://doi.org/10.2174/1570180815666180502093039
https://doi.org/10.2174/1570180815666180502093039
Akademický článek
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Autor:
Lapinsh, Maris, Prusis, Peteris, Gutcaits, Alexandrs, Lundstedt, Torbjörn, Wikberg, Jarl E.S. *
Publikováno v:
In BBA - General Subjects 2001 1525(1):180-190
Publikováno v:
QSAR & Combinatorial Science. 25:134-146
This article reviews recent advances towards an understanding of the transmembrane structure, its activation and binding sites of family 3 G-Protein-Coupled Receptors (3-GPCRs). First, the prediction of their 3D structure via homology models based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cb35230825dc1932daf202fb0f36b10
https://doi.org/10.1002/qsar.200510139
https://doi.org/10.1002/qsar.200510139
Autor:
Peteris Prusis, Claes Post, Maris Lapinsh, Jarl E. S. Wikberg, Alexandrs Gutcaits, Torbjörn Lundstedt
Publikováno v:
Protein Science. 11:795-805
We have developed an alignment-independent method for classification of G-protein coupled receptors (GPCRs) according to the principal chemical properties of their amino acid sequences. The method relies on a multivariate approach where the primary a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f90ce5f987043d51b6312f7b7bcfe8
https://doi.org/10.1110/ps.2500102
https://doi.org/10.1110/ps.2500102
Autor:
Camillo Rosano, Jie Xia, David Rodriguez, Manuel Pastor, Stefano Moro, Ajit Jadhav, Balaji Selvam, Sebastien Fiorucci, Ingebrigt Sylte, Serge Antonczak, Vsevolod Katritch, Serdar Durdagi, Ki Chul Park, Gerard Van Westen, Henri Xhaard, Raymond Stevens, Jiye Shi, Philip Biggin, Davide Sabbadin, SHUGUANG YUAN, Slawomir Filipek, David Gloriam, Antonella Ciancetta, Marek Bajda, Supriyo Bhattacharya, Hahnbeom Park, Jens Carlsson, Aleksandrs Gutcaits, Bartosz Trzaskowski, Jianyi Yang, William Pitt, Dorota Latek, Liliana Halip, Elizabeth Nguyen, Irina Kufareva, Noel Southall, Joaquin Ambia, Woong-Hee Shin, Jana Selent, Uddhavesh Sonavane, Marco Ponassi, Julien Diharce, Jose Manuel Perez-Aguilar, Nicos Petasis, Sergei Grudinin
Publikováno v:
Structure
Structure, Elsevier (Cell Press), 2014, 22 (8), pp.1120-1139. ⟨10.1016/j.str.2014.06.012⟩
Structure Fold Design
Structure, 2014, 22 (8), pp.1120-1139. ⟨10.1016/j.str.2014.06.012⟩
Structure (London, England : 1993), vol 22, iss 8
Structure, Elsevier (Cell Press), 2014, 22 (8), pp.1120-1139. ⟨10.1016/j.str.2014.06.012⟩
Structure Fold Design
Structure, 2014, 22 (8), pp.1120-1139. ⟨10.1016/j.str.2014.06.012⟩
Structure (London, England : 1993), vol 22, iss 8
International audience; Despite tremendous successes of GPCR crystallography, the receptors with available structures represent only a small fraction of human GPCRs. An important role of the modeling community is to maximize structural insights for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422429330d92f002e3e5f7e27319a9f5
https://doi.org/10.1016/j.str.2014.06.012
https://doi.org/10.1016/j.str.2014.06.012
Publikováno v:
Chemistry of Heterocyclic Compounds. 37:872-875
A series of 2-hydroxy-, 2-chloro-, and 2-(2-hydroxyethylamino)-6-aryl-4-polyfluoroalkyl-3-cyanopyridines has been synthesized. The latter react with phosphorus oxychloride to give fluorine containing 2,3-dihydroimidazo[1,2-a]pyridines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::343c19c1d8d66a6b736d0ae32bdd0774
https://doi.org/10.1023/a:1012455709358
https://doi.org/10.1023/a:1012455709358
Autor:
Tatjana Sjakste, Nikolajs Sjakste, Aleksandrs Gutcaits, Yegor S. Vassetzky, K. Bielskiene, Danute Labeikyte, Lida Bagdoniene
Publikováno v:
Gene. 492(1)
Tightly bound to DNA proteins (TBPs) are a protein group that remains attached to DNA after its deproteinization by phenol, chloroform or salting-out. TBP are bound to DNA with covalent phosphotriester or non-covalent ion and hydrogen bonds. They app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a7ebec45bef93363f7d63be5040576
https://pubmed.ncbi.nlm.nih.gov/22001404
https://pubmed.ncbi.nlm.nih.gov/22001404