A synthetic transcription platform for programmable gene expression in mammalian cells.

Autor: Chen WCW; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. William.Chen@usd.edu.; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. William.Chen@usd.edu.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. William.Chen@usd.edu.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, 02114, USA. William.Chen@usd.edu.; Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD, 57069, USA. William.Chen@usd.edu., Gaidukov L; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Lai Y; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Wu MR; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA., Cao J; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Gutbrod MJ; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, 02139, USA., Choi GCG; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Laboratory of Combinatorial Genetics and Synthetic Biology, School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China., Utomo RP; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Biochemistry, Wellesley College, Wellesley, MA, 02481, USA., Chen YC; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan., Wroblewska L; Pfizer Inc., Cambridge, MA, 02139, USA., Kellis M; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, 02139, USA., Zhang L; Pfizer Inc., Andover, MA, 01810, USA., Weiss R; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Lu TK; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. tim@lugroup.org.; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. tim@lugroup.org.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. tim@lugroup.org.

Publikováno v: Nature communications [Nat Commun] 2022 Oct 18; Vol. 13 (1), pp. 6167. Date of Electronic Publication: 2022 Oct 18.

Conserved chromosomal functions of RNA interference.

Autor: Gutbrod MJ; Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Martienssen RA; Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. martiens@cshl.edu.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. martiens@cshl.edu.

Publikováno v: Nature reviews. Genetics [Nat Rev Genet] 2020 May; Vol. 21 (5), pp. 311-331. Date of Electronic Publication: 2020 Feb 12.