Management of liver failure in general intensive care unit

Autor: Paugam-Burtz, C., Levesque, E., Louvet, A., Thabut, D., Amathieu, R., Bureau, C., Camus, C., Chanques, G., Faure, S., Ferrandière, M., Francoz, C., Galbois, A., Gustot, T., Ichai, C., Ichai, P., Jaber, S., Lescot, T., Moreau, R., Roullet, S., Saliba, F., Thévenot, T., Velly, L., Weiss, E.

Publikováno v: In Anaesthesia Critical Care & Pain Medicine February 2020 39(1):143-161

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Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF (vol 72, pg 688, 2020)

Autor: Moreau, R, Claria, J, Aguilar, F, Fenaille, F, Lozano, JJ, Junot, C, Colsch, B, Caraceni, P, Trebicka, J, Pavesi, M, Alessandria, C, Nevens, F, Saliba, F, Welzel, TM, Albillos, A, Gustot, T, Fernandez, J, Moreno, C, Baldassarre, M, Zaccherini, G, Piano, S, Montagnese, S, Vargas, V, Genesca, J, Sola, E, Bernal, W, Butin, N, Hautbergue, T, Cholet, S, Castelli, F, Jansen, C, Steib, C, Campion, D, Mookerjee, R, Rodriguez-Gandia, M, Soriano, G, Durand, F, Benten, D, Banares, R, Stauber, RE, Gronbaek, H, Coenraad, MJ, Gines, P, Gerbes, A, Jalan, R, Bernardi, M, Arroyo, V, Angeli, P, CANONIC Study, Grifols Chair European

Publikováno v: JOURNAL OF HEPATOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6faed732bd9302045485ae00a39b6167
https://doi.org/10.1016/j.jhep.2020.03.002

Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis

Autor: Claria, J., Moreau, R., Fenaille, F., Amoros, A., Junot, C., Gronbaek, H., Coenraad, M.J., Pruvost, A., Ghettas, A., Chu-Van, E., Lopez-Vicario, C., Oettl, K., Caraceni, P., Alessandria, C., Trebicka, J., Pavesi, M., Deulofeu, C., Albillos, A., Gustot, T., Welzel, T.M., Fernandez, J., Stauber, R.E., Saliba, F., Butin, N., Colsch, B., Moreno, C., Durand, F., Nevens, F., Banares, R., Benten, D., Gines, P., Gerbes, A., Jalan, R., Angeli, P., Bernardi, M., Arroyo, V., EASL Clif Consortium, Grifols Chair European Fdn Study C

Publikováno v: Clària, J, Moreau, R, Fenaille, F, Amorós, A, Junot, C, Gronbaek, H, Coenraad, M J, Pruvost, A, Ghettas, A, Chu-Van, E, López-Vicario, C, Oettl, K, Caraceni, P, Alessandria, C, Trebicka, J, Pavesi, M, Deulofeu, C, Albillos, A, Gustot, T, Welzel, T M, Fernández, J, Stauber, R E, Saliba, F, Butin, N, Colsch, B, Moreno, C, Durand, F, Nevens, F, Bañares, R, Benten, D, Ginès, P, Gerbes, A, Jalan, R, Angeli, P, Bernardi, M, Arroyo, V & CANONIC Study Investigators of the EASL Clif Consortium Grifols Chair and the European Foundation for the Study of Chronic Liver Failure (EF Clif) 2019, ' Orchestration of Tryptophan-Kynurenine pathway, acute decompensation and acute-on-chronic liver failure in cirrhosis ', Hepatology, vol. 69, no. 4, pp. 1686-1701 . https://doi.org/10.1002/hep.30363
Hepatology, 69(4), 1686-1701
Hepatology
Hepatology, Wiley-Blackwell, 2019, 69 (4), pp.1686-1701. ⟨10.1002/hep.30363⟩
Hepatology, 69 (4
Hepatology, 2019, 69 (4), pp.1686-1701. ⟨10.1002/hep.30363⟩

Systemic inflammation (SI) is involved in the pathogenesis of acute decompensation (AD) and acute-on-chronic liver failure (ACLF) in cirrhosis. In other diseases, SI activates tryptophan (Trp) degradation through the kynurenine pathway (KP), giving r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc898f115816418b6c4fd3aa291c70a8
https://doi.org/10.1002/hep.30363

PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases

Autor: Yang, J., Trepo, E., Nahon, P., Cao, Q., Moreno, C., LETOUZE, E., Imbeaud, S., Gustot, T., DEVIERE, J., Debette, Stephanie, Amouyel, P., Bioulac-Sage, P., CALDERARO, J., Ganne-Carrie, N., Laurent, A., Blanc, J. F., GUYOT, E., Sutton, A., Ziol, M., ZUCMAN-ROSSI, J., Nault, J. C.

Publikováno v: International Journal of Cancer
International Journal of Cancer, Wiley, 2019, 144 (3), pp.533-544. ⟨10.1002/ijc.31910⟩

Few single nucleotide polymorphisms (SNPs) have been reproducibly associated with hepatocellular carcinoma (HCC). Our aim was to test the association between nine SNPs and HCC occurrence. SNPs in genes linked to HCC (DEPDC5, GRIK1, KIF1B, STAT4, MICA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2ea738cb4744db157c0daa683fbc1def
https://hal.archives-ouvertes.fr/hal-03159258