Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gustavo Zamberlam"'
Autor:
Michael Bérubé, Atefeh Abedini, Evelyne Lapointe, Samuel Gusscott, Julie Brind’Amour, Gustavo Zamberlam, Derek Boerboom
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Secreted frizzled-related proteins (SFRPs) comprise a family of WNT signaling antagonists whose roles in the ovary are poorly understood. Sfrp4-null mice were previously found to be hyperfertile due to an enhanced granulosa cell r
Externí odkaz:
https://doaj.org/article/29b5ae788f694849a045aebfa47db228
Autor:
Esdras Corrêa Dos Santos, Alexandre Boyer, Guillaume St-Jean, Natalia Jakuc, Nicolas Gévry, Christopher A. Price, Gustavo Zamberlam
Publikováno v:
Animals, Vol 13, Iss 18, p 2851 (2023)
Cystic ovarian disease (COD) in dairy cattle is characterized by preovulatory follicles that become cysts, fail to ovulate and persist in the ovary; consequently, interfering with normal ovarian cyclicity. The intraovarian key players that orchestrat
Externí odkaz:
https://doaj.org/article/d7535ad156904065ad8300891f7e69c5
Autor:
Karine de Vargas Aires, Esdras Correa dos Santos, Ana Paula da Silva, Igor Gabriel Zappe, Leonardo Guedes de Andrade, Carolina dos Santos Amaral, Mariani Farias Fiorenza, Paulo Bayard Dias Gonçalves, Guillaume St-Jean, Valério Marques Portela, Gustavo Zamberlam, Alfredo Quites Antoniazzi
Publikováno v:
Reproduction, Fertility and Development. 34:1023-1033
Context The establishment of pregnancy in cows requires uterine activity regulation of the main Hippo signalling effector yes-associated protein 1 (YAP). It remains unknown (1) how YAP activity at the corpus luteum (CL) correlates with early pregnanc
Autor:
Júlia Koch, Valério Marques Portela, Esdras Corrêa Dos Santos, Daniele Missio, Leonardo Guedes de Andrade, Zigomar da Silva, Bernardo Garziera Gasperin, Alfredo Quites Antoniazzi, Paulo Bayard Dias Gonçalves, Gustavo Zamberlam
Publikováno v:
J Assist Reprod Genet
PURPOSE: To determine if the inhibition of the interaction between the Hippo effector YAP or its transcriptional co-activator TAZ with the TEAD family of transcription factors is critical for the cumulus expansion–related events induced by the EGF
Publikováno v:
Reproductive Sciences.
Ovulatory disorders are a major cause of infertility in humans as well as economically important species. In physiological conditions, the LH surge induces the expression of epidermal growth factor (EGF)-like ligands that activate the EGR receptor (E
Autor:
Leonardo Guedes de Andrade, Valério Marques Portela, Esdras Corrêa Dos Santos, Karine de Vargas Aires, Rogério Ferreira, Daniele Missio, Zigomar da Silva, Júlia Koch, Alfredo Quites Antoniazzi, Paulo Bayard Dias Gonçalves, Gustavo Zamberlam
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14160
The molecular mechanisms that drive the granulosa cells’ (GC) differentiation into a more estrogenic phenotype during follicular divergence and establishment of follicle dominance have not been completely elucidated. The main Hippo signaling effect
Autor:
Nour Abou Nader, Étienne Blais, Guillaume St-Jean, Derek Boerboom, Gustavo Zamberlam, Alexandre Boyer
Publikováno v:
Journal of the Endocrine Society. 7
Recent conditional knockout of core components of the Hippo signaling pathway in the adrenal gland of mice has demonstrated that this pathway must be tightly regulated to ensure proper development and maintenance of the adrenal cortex. We report here
Publikováno v:
International Journal of Molecular Sciences. 23:14388
The cortex of the adrenal gland is organized into concentric zones that produce distinct steroid hormones essential for body homeostasis in mammals. Mechanisms leading to the development, zonation and maintenance of the adrenal cortex are complex and
Autor:
Nour Abou Nader, Amélie Ménard, Adrien Levasseur, Guillaume St-Jean, Derek Boerboom, Gustavo Zamberlam, Alexandre Boyer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13585
Hippo signaling plays an essential role in the development of numerous tissues. Although it was previously shown that the transcriptional effectors of Hippo signaling Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif
Autor:
Ariane Lalonde-Larue, Alexandre Boyer, Esdras Corrêa Dos Santos, Derek Boerboom, Daniel J Bernard, Gustavo Zamberlam
Publikováno v:
Endocrinology
The Hippo transcriptional coactivators YAP and TAZ exert critical roles in morphogenesis, organ size determination and tumorigenesis in many tissues. Although Hippo kinase cascade activity was recently reported in the anterior pituitary gland in mice