Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gustavo Scheiffer"'
Autor:
Gustavo Scheiffer, Karime Zeraik Abdalla Domingues, Daniela Gorski, Alexandre de Fátima Cobre, Raul Edison Luna Lazo, Helena Hiemisch Lobo Borba, Luana Mota Ferreira, Roberto Pontarolo
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 23, Pp 1117-1169 (2024)
The shortage of treatment options for leishmaniasis, especially those easy to administer and viable for deployment in the world's poorest regions, highlights the importance of employing these strategies to cost-effectively investigate repurposing can
Externí odkaz:
https://doaj.org/article/3d49c0ed9fde4db5b6d030386a830199
Autor:
Julia de Paula Dutra, Gustavo Scheiffer, Thales Kronenberger, Lucas Julian Cruz Gomes, Isadora Zanzarini, Kelly Karoline dos Santos, Arun K. Tonduru, Antti Poso, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Glaucio Valdameri, Vivian Rotuno Moure
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 1155-1172 (2023)
A current clinical challenge in cancer is multidrug resistance (MDR) mediated by ABC transporters. Breast cancer resistance protein (BCRP) or ABCG2 transporter is one of the most important ABC transporters implicated in MDR and the use of inhibitors
Externí odkaz:
https://doaj.org/article/89c372996acc4eafb0e43f13022f3e07
Autor:
Ingrid Fatima Zattoni, Letícia Carani Delabio, Julia de Paula Dutra, Diogo Henrique Kita, Gustavo Scheiffer, Marina Hembecker, Giovana da Silva Pereira, Vivian Rotuno Moure, Glaucio Valdameri
Publikováno v:
European journal of medicinal chemistry. 237
The primary source of failure of cancer therapies is multidrug resistance (MDR), which can be caused by different mechanisms, including the overexpression of ABC transporters in cancer cells. Among the 48 human ABC proteins, the breast cancer resista