Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gustavo Pereira de Almeida"'
Autor:
Sophia Groh, Anna Viktoria Milton, Lisa Katherina Marinelli, Cara V. Sickinger, Angela Russo, Heike Bollig, Gustavo Pereira de Almeida, Andreas Schmidt, Ignasi Forné, Axel Imhof, Gunnar Schotta
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Endogenous retroviruses (ERVs) compose a significant portion of mammalian genomes; however, how ERVs are regulated is not well known. Here the authors performed a genome-wide sgRNA screen to identify Morc3 as a mediator of ERV silencing. They show Mo
Externí odkaz:
https://doaj.org/article/7babdca1f6d949e89f3a1f776c0144b2
Autor:
Madlaina, von Hoesslin, Miriam, Kuhlmann, Gustavo Pereira, de Almeida, Kristiyan, Kanev, Christine, Wurmser, Ann-Katrin, Gerullis, Patrick, Roelli, Jacqueline, Berner, Dietmar, Zehn
Publikováno v:
Science immunology. 7(77)
Resident T lymphocytes (T
Autor:
Miriam Kuhlmann, Daphne Del Carmen Kolland, Gustavo Pereira de Almeida, Christian Hoffmann, Madlaina von Hoesslin, Jacqueline Berner, Christine Wurmser, Caspar Ohnmacht, Dietmar Zehn
Prolonged antigen exposure in chronic viral infections reduces the effector capacity of cytotoxic T cells - a phenomenon known as T cell exhaustion. High viral titer, strong TCR stimulation, and high antigen concentrations associated with strong infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb9f8f18471170a77d226176679ba0be
https://doi.org/10.1101/2022.10.03.510696
https://doi.org/10.1101/2022.10.03.510696
Publikováno v:
Nature Immunology, 23
Virus-specific CD8(+) T cells that differentiate in the context of resolved versus persisting infections exhibit divergent phenotypic and functional characteristics, which suggests that their differentiation trajectories are governed by distinct cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470b9d9e7ccf1c07ddb67e55ff41c044
https://hdl.handle.net/20.500.11850/552647
https://hdl.handle.net/20.500.11850/552647
Publikováno v:
Nature immunology. 23(6)
Virus-specific CD8
Autor:
Sophia Groh, Anna Viktoria Milton, Lisa Katherina Marinelli, Cara V. Sickinger, Angela Russo, Heike Bollig, Gustavo Pereira de Almeida, Andreas Schmidt, Ignasi Forné, Axel Imhof, Gunnar Schotta
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Endogenous retroviruses (ERVs) comprise a significant portion of mammalian genomes. Although specific ERV loci feature regulatory roles for host gene expression, most ERV integrations are transcriptionally repressed by Setdb1-mediated H3K9me3 and DNA
Autor:
Gustavo Pereira de Almeida, Ignasi Forné, Sophia Groh, Lisa Katherina Marinelli, Andreas Schmidt, Gunnar Schotta, Cara V. Sickinger, Anna Viktoria Milton, Heike Bollig, Axel Imhof
Endogenous retroviruses (ERVs) comprise a significant portion of mammalian genomes. Although, specific ERV loci feature regulatory roles for host gene expression, most ERV integrations are transcriptionally repressed by Setdb1 mediated H3K9me3 and DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::930d267089ce00c4e0b8fe506e8137fc
https://doi.org/10.1101/2020.11.12.380204
https://doi.org/10.1101/2020.11.12.380204
Autor:
Maria Hinterberger, Joachim Ellwart, Meinrad Busslinger, Anja Ebert, Gustavo Pereira de Almeida, Alessandra Pasquarella, Maryam Kazerani, Gunnar Schotta, Alexander Nuber, Ludger Klein
Publikováno v:
Development 143, 1788-1799 (2016)
Europe PubMed Central
Europe PubMed Central
The H3K9me3-specific histone methyltransferase Setdb1 impacts on transcriptional regulation by repressing both developmental genes and retrotransposons. How impaired retrotransposon silencing may lead to developmental phenotypes is currently unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95dd1897d31876749959149dde528fdf
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=48193
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=48193
Publikováno v:
Epigenomics. 5(6)
Epigenetic mechanisms are crucial to stabilize cell type-specific gene-expression programs. However, during differentiation, these programs need to be modified – a complex process that requires dynamic but tightly controlled rearrangements in the e