Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gustavo Lorente"'
Autor:
Ricardo Ramón Montesdeoca Parraga, Karen Piloso Chávez, Taimy Hernández Sariego, Ileana Lemoine Yanes, Miriam Camejo Pupo, Gustavo Lorente González, Isnel Benítez Cortes, María García Garay
Publikováno v:
Siembra, Vol 7, Iss 2 (2020)
Se evalúo la calidad e indicadores de eficiencia tecnológica de la producción del queso semiduro Gouda en la Fábrica de Quesos Sibanicú, para la determinación de las mejores condiciones operacionales que permitan una adecuada conservación. Se
Externí odkaz:
https://doaj.org/article/1ed613dc7d874f959934cdd957ae8698
Autor:
Charles P. Hart, Mark D. Matteucci, Peter M. Glazer, Gregory C. Stachelek, Adam V. Patterson, Robert F. Anderson, Andrej Maroz, Christopher P. Guise, Alexandra M. Mowday, Xiaohong Cai, Jian-Xin Duan, Gustavo Lorente, Leslie Lan, Monica Banica, Deepthi Bhupathi, James W. Evans, Fanying Meng
TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard currently undergoing clinical evaluation. Here, we describe broad-spectrum activity, hypoxia-selective activation, and mechanism of action of TH-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1647daf3bd322e5dd347e898918fddfd
https://doi.org/10.1158/1535-7163.c.6535963
https://doi.org/10.1158/1535-7163.c.6535963
Autor:
Karen Johana Piloso Chávez, Miriam Camejo Pupo, Ricardo Ramón Montesdeoca Párraga, Ileana Lemoine Yanes, Taimy Hernández Sariego, Gustavo Lorente González, María García Garay, Isnel Benítez Cortés
Publikováno v:
Siembra, Vol 7, Iss 2 (2020)
espanolSe evaluo la calidad e indicadores de eficiencia tecnologica de la produccion del queso semiduro Gouda en la Fabrica de Quesos Sibanicu, para la determinacion de las mejores condiciones operacionales que permitan una adecuada conservacion. Se
Autor:
Jorge Orlay Serrano, Asiel Villares-Garachana, Nelson Correa-Herrera, Abel González-Morales, Lisbet Pérez-Bonachea, Lázaro Hernández, Gustavo Lorente, Elliosha Hajari, Norge Fonseca-Fuentes, Jorge Martínez-Melo, José Carlos Lorenzo
Publikováno v:
Tropical Animal Health and Production. 54
One of the projected effects of climate change is a reduction in rainfall in certain regions of the world. Hence, the agricultural and livestock sectors will have to cope with increasing incidences of water shortage whilst still maintaining productiv
Autor:
Jorge Orlay Serrano, Aliana López Mayea, Asiel Villares-Garachana, Nelson Correa-Herrera, Abel González-Morales, Lisbet Pérez-Bonachea, Lázaro Hernández, Gustavo Lorente, Elliosha Hajari, Norge Fonseca-Fuentes, Jorge Martínez-Melo, José Carlos Lorenzo
Publikováno v:
Small Ruminant Research. 210:106679
Publikováno v:
Journal of Neuro-Oncology. 76:239-248
Invasion of glioma cells involves the attachment of invading tumor cells to extracellular matrix (ECM), disruption of ECM components, and subsequent cell penetration into adjacent brain structures. Discoidin domain receptor 1 (DDR1) tyrosine kinases
Autor:
Gustavo Lorente, James W. Evans, Mark D. Matteucci, Peter M. Glazer, Fanying Meng, Andrej Maroz, Christopher P. Guise, Adam V. Patterson, Xiaohong Cai, Jian-Xin Duan, Monica Banica, Robert F. Anderson, Leslie Lan, Charles P. Hart, Gregory C. Stachelek, Alexandra M. Mowday, Deepthi Bhupathi
Publikováno v:
Molecular cancer therapeutics. 11(3)
TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard currently undergoing clinical evaluation. Here, we describe broad-spectrum activity, hypoxia-selective activation, and mechanism of action of TH-
Autor:
Stew Kroll, Sant P. Chawla, Gustavo Lorente, Daniel A. Rushing, James E. Butrynski, Kristen N. Ganjoo, Douglas Adkins, Virginia K. Langmuir, Scott H. Okuno, Lee D. Cranmer
Publikováno v:
Oncology. 80(1-2)
Purpose: The purpose of this study was to determine the dose-limiting toxicities (DLT), maximum tolerated dose (MTD), safety, pharmacokinetics and preliminary activity of TH-302, a hypoxia-activated prodrug, in combination with doxorubicin in patient
Autor:
Mark D. Matteucci, Zhijian Yang, Jian-Xin Duan, Timothy Friend Stanton, Hailong Jiao, Gustavo Lorente, Charles P. Hart, Monica Banica, Xiao-Ming Li, Robert M. Hoffman, Jacob Kaizerman, Jinwei Wang, James W. Evans, Leslie Lan, W. Steve Ammons, Don Jung, Huaiyu Ma
Publikováno v:
Journal of medicinal chemistry. 51(8)
A series of achiral hypoxia-activated prodrugs were synthesized on the basis of the DNA cross-linking toxin of the prodrug, ifosfamide. The hypoxia-selective cytotoxicity of several of the compounds was improved over previously reported racemic mixtu
Publikováno v:
Cancer research. 66(4)
The receptor protein tyrosine phosphatase β (RPTPβ) is a functional biomarker for several solid tumor types. RPTPβ expression is largely restricted to the central nervous system and overexpressed primarily in astrocytic tumors. RPTPβ is known to