Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gustavo H. G. Trossini"'
Publikováno v:
Orbital: The Electronic Journal of Chemistry, Vol 12, Iss 3, Pp 108-117 (2020)
Malaria is the most devastating tropical disease in the world and this scenario is worsened by the absence of effective treatment. However, the plasmodium resistance to artemisinin does not show clinical relevance. The drug mechanism of action is ass
Externí odkaz:
https://doaj.org/article/53c9c1c4f97a4a82b0082fbfba7fb1a0
Autor:
Ana Caroline Barbosa França, Kátia Sanches Françoso, Rodolfo Ferreira Marques, Gustavo H. G. Trossini, Renan A. Gomes, Marinete M. Póvoa, Maristela G. Cunha, Eduardo L. V. Silveira, Irene S. Soares
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Malaria is a human parasitic disease distributed in many tropical countries and caused by various Plasmodium species. Plasmodium vivax has the largest geographical distribution of the Plasmodium species and is predominant in the Americas, including B
Externí odkaz:
https://doaj.org/article/88b258c5464845de9d2f43aeadbc40d1
Publikováno v:
Molecules, Vol 19, Iss 7, Pp 10546-10562 (2014)
Infectious diseases such as trypanosomiasis and leishmaniasis are considered neglected tropical diseases due the lack for many years of research and development into new drug treatments besides the high incidence of mortality and the lack of current
Externí odkaz:
https://doaj.org/article/91e46f92a7c64a31a3c554e8105eb6c7
Publikováno v:
Química Nova, Vol 36, Iss 1, Pp 143-152 (2013)
The discovery of ferrocene marked one of the points of departure for modern organometallic chemistry. In general, the compounds of ferrocene derivatives are widely applied in several areas. One of the most important applications of ferrocene is the d
Externí odkaz:
https://doaj.org/article/f736585e9ab84c5b97809d1b869272fa
Autor:
Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Mauro S. Nogueira, Gustavo H. G. Trossini, Thomas J. Schmidt
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3721 (2018)
Three complementary quantitative structure⁻activity relationship (QSAR) methodologies, namely, regression modeling based on (i) “classical„ molecular descriptors, (ii) 3D pharmacophore features, and (iii) 2D molecular holograms (HQSAR) were emp
Externí odkaz:
https://doaj.org/article/6991185f1d7b4194af4c4012b54b5c53
Publikováno v:
Molecules, Vol 22, Iss 12, p 1884 (2017)
Cyanobacteria are able to produce a wide range of secondary metabolites, including toxins and protease inhibitors, with diverse biological activities. Microginins are small linear peptides biosynthesized by cyanobacteria species that act against prot
Externí odkaz:
https://doaj.org/article/3aad23d95349493b834c213ccd784333
Autor:
Renato Grillo, Nathalie F. S. de Melo, Leonardo Fernandes Fraceto, Charles L. Brito, Gustavo H. G. Trossini, Carla M. S. Menezes, Elizabeth Igne Ferreira, Carolina Morales Moraes
Publikováno v:
Química Nova, Vol 31, Iss 2, Pp 290-295 (2008)
Hydroxymethylnitrofurazone (NFOH) is a prodrug that is active against Trypanosoma cruzi. It however presents low solubility and high toxicity. Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) can be used as a drug-delivery system for NFOH modifying its p
Externí odkaz:
https://doaj.org/article/773dd04cb898481cb6c8c2f72349ec0d
Autor:
Ana Caroline Barbosa, França, Kátia Sanches, Françoso, Rodolfo Ferreira, Marques, Gustavo H G, Trossini, Renan A, Gomes, Marinete M, Póvoa, Maristela G, Cunha, Eduardo L V, Silveira, Irene S, Soares
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Malaria is a human parasitic disease distributed in many tropical countries and caused by various Plasmodium species. Plasmodium vivax has the largest geographical distribution of the Plasmodium species and is predominant in the Americas, including B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7835fd3d97255387a0add1ae7aaa5948
https://pubmed.ncbi.nlm.nih.gov/33796476
https://pubmed.ncbi.nlm.nih.gov/33796476
Autor:
Njogu M, Kimani, Josphat C, Matasyoh, Marcel, Kaiser, Mauro S, Nogueira, Gustavo H G, Trossini, Thomas J, Schmidt
Publikováno v:
International Journal of Molecular Sciences
Three complementary quantitative structure–activity relationship (QSAR) methodologies, namely, regression modeling based on (i) “classical” molecular descriptors, (ii) 3D pharmacophore features, and (iii) 2D molecular holograms (HQSAR) were emp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00a4af735eebbf485d861fac1925fa46
https://pubmed.ncbi.nlm.nih.gov/30467296
https://pubmed.ncbi.nlm.nih.gov/30467296
Autor:
Wender A. Silva, Lennine R. Melo, Camilla C. C. Silva, Guilherme R. Oliveira, Gustavo H. G. Trossini
Publikováno v:
Proceedings of the 15th Brazilian Meeting on Organic Synthesis Proceedings.
Chagas’ disease is an infection caused by the protozoan parasite Trypanosoma cruzi, considered by World Health Organization as a neglected disease it causes thousands of deaths each year. Only drugs, nifurtimox and benznidazole, are using against t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d86a41fdc5f8726f99cf345cda2921e
https://doi.org/10.5151/chempro-15bmos-bmos2013_2013915192751
https://doi.org/10.5151/chempro-15bmos-bmos2013_2013915192751