Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Gustavo Gutierrez-Cruz"'
Autor:
Maria Casal-Dominguez, Iago Pinal-Fernandez, Katherine Pak, Sandra Muñoz-Braceras, Jose C. Milisenda, Jiram Torres-Ruiz, Stefania Dell′Orso, Faiza Naz, Gustavo Gutierrez-Cruz, Yaiza Duque-Jaimez, Ana Matas-Garcia, Laura Valls-Roca, Gloria Garrabou, Ernesto Trallero-Araguas, Brian Walitt, Lisa Christopher-Stine, Thomas E. Lloyd, Julie J. Paik, Jemima Albayda, Andrea Corse, Josep Maria Grau, Albert Selva-O’Callaghan, Andrew L. Mammen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Complement proteins are deposited in the muscles of patients with myositis. However, the local expression and regulation of complement genes within myositis muscle have not been well characterized. In this study, bulk RNA sequencing (RNAseq)
Externí odkaz:
https://doaj.org/article/432560f2a1924ebb82edb93b6abbedca
Autor:
Sandra Muñoz-Braceras, Iago Pinal-Fernandez, Maria Casal-Dominguez, Katherine Pak, José César Milisenda, Shajia Lu, Massimo Gadina, Faiza Naz, Gustavo Gutierrez-Cruz, Stefania Dell’Orso, Jiram Torres-Ruiz, Josep Maria Grau-Junyent, Albert Selva-O’Callaghan, Julie J. Paik, Jemima Albayda, Lisa Christopher-Stine, Thomas E. Lloyd, Andrea M. Corse, Andrew L. Mammen
Publikováno v:
Cells, Vol 12, Iss 17, p 2198 (2023)
Dermatomyositis (DM), antisynthetase syndrome (AS), immune-mediated necrotizing myopathy (IMNM), and inclusion body myositis (IBM) are four major types of idiopathic inflammatory myopathy (IIM). Muscle biopsies from each type of IIM have unique trans
Externí odkaz:
https://doaj.org/article/430bca4e170c4fd7ba24d5229acce44e
Autor:
Hirotsugu Oda, David B. Beck, Hye Sun Kuehn, Natalia Sampaio Moura, Patrycja Hoffmann, Maria Ibarra, Jennifer Stoddard, Wanxia Li Tsai, Gustavo Gutierrez-Cruz, Massimo Gadina, Sergio D. Rosenzweig, Daniel L. Kastner, Luigi D. Notarangelo, Ivona Aksentijevich
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: HOIP is the catalytic subunit of the linear ubiquitination chain assembly complex (LUBAC) that is essential for NF-κB signaling and thus proper innate and adaptive immunity. To date only one patient with HOIP deficiency has been reported
Externí odkaz:
https://doaj.org/article/8af4a14f355248ea9daee0527dcd8fbe
Autor:
Aster H. Juan, Stan Wang, Kyung Dae Ko, Hossein Zare, Pei-Fang Tsai, Xuesong Feng, Karinna O. Vivanco, Anthony M. Ascoli, Gustavo Gutierrez-Cruz, Jordan Krebs, Simone Sidoli, Adam L. Knight, Roger A. Pedersen, Benjamin A. Garcia, Rafael Casellas, Jizhong Zou, Vittorio Sartorelli
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1369-1382 (2016)
Summary: The polycomb repressive complex 2 (PRC2) methylates lysine 27 of histone H3 (H3K27) through its catalytic subunit Ezh2. PRC2-mediated di- and tri-methylation (H3K27me2/H3K27me3) have been interchangeably associated with gene repression. Howe
Externí odkaz:
https://doaj.org/article/4790dc579ba94415bc2378a7c18b3b48
Autor:
Stefania Dell’Orso, A. Hongjun Wang, Han-Yu Shih, Kayoko Saso, Libera Berghella, Gustavo Gutierrez-Cruz, Andreas G. Ladurner, John J. O’Shea, Vittorio Sartorelli, Hossein Zare
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1156-1168 (2016)
Summary: Histone variants complement and integrate histone post-translational modifications in regulating transcription. The histone variant macroH2A1 (mH2A1) is almost three times the size of its canonical H2A counterpart, due to the presence of an
Externí odkaz:
https://doaj.org/article/f10a405ef3944f6d8b32d3ea4d862cdf
Autor:
Iago Pinal-Fernandez, Angela Quintana, Jose Cesar Milisenda, Maria Casal-Dominguez, Sandra Muñoz-Braceras, Assia Derfoul, Jiram Torres-Ruiz, Katherine Pak, Stefania Dell'Orso, Faiza Naz, Gustavo Gutierrez-Cruz, Margherita Milone, Shahar Shelly, Yaiza Duque-Jaimez, Ester Tobias-Baraja, Ana Matas-Garcia, Gloria Garrabou, Joan Padrosa, Javier Ros, Ernesto Trallero-Araguás, Brian Walitt, Lisa Christopher-Stine, Thomas E Lloyd, Chen Zhao, Shannon Swift, Arun Rajan, Josep Maria Grau-Junyent, Albert Selva-O'Callaghan, Teerin Liewluck, Andrew Lee Mammen
Publikováno v:
Annals of the Rheumatic Diseases. 82:829-836
ObjectivesInflammatory myopathy or myositis is a heterogeneous family of immune-mediated diseases including dermatomyositis (DM), antisynthetase syndrome (AS), immune-mediated necrotising myopathy (IMNM) and inclusion body myositis (IBM). Immune chec
Autor:
Iago Pinal-Fernandez, Angela Quintana, Jose C. Milisenda, Maria Casal-Dominguez, Sandra Muñoz-Braceras, Assia Derfoul, Jiram Torres-Ruiz, Katherine Pak, Stefania Del Orso, Faiza Naz, Gustavo Gutierrez-Cruz, Margherita Milone, Shahar Shelly, Yaiza Duque-Jaimez, Ester Tobias-Baraja, Ana Matas-Garcia, Gloria Garrabou, Joan Padrosa, Javier Ros, Ernesto Trallero-Araguás, Brian Walitt, Lisa Christopher-Stine, Thomas E. Lloyd, Chen Zhao, Shannon Swift, Arun Rajan, Josep Maria Grau, Albert Selva-O’Callaghan, Teerin Liewluck, Andrew L. Mammen
ObjectivesInflammatory myopathy or myositis is a heterogeneous family of immune-mediated diseases including dermatomyositis (DM), antisynthetase syndrome (AS), immune-mediated necrotizing myopathy (IMNM), and inclusion body myositis (IBM). Immune che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0e51a0338d822551f4edb1396c23f81
https://doi.org/10.1101/2022.12.12.520136
https://doi.org/10.1101/2022.12.12.520136
Autor:
Iago Pinal-Fernandez, Jose Cesar Milisenda, Katherine Pak, Sandra Muñoz-Braceras, Maria Casal-Dominguez, Jiram Torres-Ruiz, Stefania Dell'Orso, Faiza Naz, Gustavo Gutierrez-Cruz, Yaiza Duque-Jaimez, Ana Matas-Garcia, Joan Padrosa, Francesc J Garcia-Garcia, Mariona Guitart-Mampel, Gloria Garrabou, Ernesto Trallero-Araguás, Brian Walitt, Julie J Paik, Jemima Albayda, Lisa Christopher-Stine, Thomas E Lloyd, Josep Maria Grau-Junyent, Albert Selva-O'Callaghan, Andrew Lee Mammen
Publikováno v:
Annals of the Rheumatic Diseases. :ard-2023
ObjectivesMyositis is a heterogeneous family of diseases including dermatomyositis (DM), immune-mediated necrotising myopathy (IMNM), antisynthetase syndrome (AS) and inclusion body myositis (IBM). Myositis-specific autoantibodies define different su
Autor:
Natasha Silke, Manfred Boehm, Amanda K. Ombrello, Ivona Aksentijevich, Deborah L. Stone, Tina Romeo, Marco J Herold, Laurens Wachsmuth, Christine Biben, Beverly K. Barham, Lin Liu, Andrew J. Gross, Sergio D. Rosenzweig, Patrycja Hoffmann, Natalia Sampaio Moura, Gustavo Gutierrez-Cruz, Daniel L. Kastner, Steven E. Boyden, Kristien J. M. Zaal, Anne K. Voss, Holly Anderton, Anne Jones, Hongying Wang, Tobias Kratina, John Silke, Michael J. Lenardo, James C. Mullikin, Kate E. Lawlor, David B. Beck, Mark D. McKenzie, Amanda Light, Anthony K. Shum, Jae Jin Chae, Massimo Gadina, Qing Zhou, Diep Chau, Gineth Pinto-Patarroyo, Hirotsugu Oda, Geryl Wood, Mary Blake, Nima Etemadi, Kristy Shield-Artin, Edwin D. Hawkins, Monique Stoffels, Cathrine Hall, Dan Yang, Wanxia Li Tsai, Hye Sun Kuehn, Natalia I. Dmitrieva, Seth L. Masters, Lixin Zheng, Andrew J. Kueh, Manolis Pasparakis, Najoua Lalaoui
Publikováno v:
Nature
Nature, vol 577, iss 7788
Nature, vol 577, iss 7788
Receptor Interacting Protein Kinase 1 (RIPK1) is a key regulator of innate immune signalling pathways. To ensure an optimal inflammatory response, RIPK1 is post-translationally regulated by well characterised ubiquitylation and phosphorylation events
The mdx mouse (C57BL/10ScSn-DMDmdx/J) is the oldest model of Duchenne muscular dystrophy (DMD). Mdx remains popular and has not been replaced by newer mouse models, despite criticisms that mdx has a nearly normal lifespan and mild pathology while DMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b994556ecd3a4e0380fae7aaa83ee29b
https://doi.org/10.1101/2021.07.16.452553
https://doi.org/10.1101/2021.07.16.452553