Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gustavo E. Carrizo"'
Autor:
Matteo Villa, David E. Sanin, Petya Apostolova, Mauro Corrado, Agnieszka M. Kabat, Carmine Cristinzio, Annamaria Regina, Gustavo E. Carrizo, Nisha Rana, Michal A. Stanczak, Francesc Baixauli, Katarzyna M. Grzes, Jovana Cupovic, Francesca Solagna, Alexandra Hackl, Anna-Maria Globig, Fabian Hässler, Daniel J. Puleston, Beth Kelly, Nina Cabezas-Wallscheid, Peter Hasselblatt, Bertram Bengsch, Robert Zeiser, Sagar, Joerg M. Buescher, Edward J. Pearce, Erika L. Pearce
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Immune cells must adapt to different environments during the course of an immune response. Here we study the adaptation of CD8+ T cells to the intestinal microenvironment and how this process shapes the establishment of the CD8+ T cell pool.
Externí odkaz:
https://doaj.org/article/94dc27161c6a48b2b42944d1f1be38af
Autor:
Joy Edwards-Hicks, Petya Apostolova, Joerg M. Buescher, Hannes Maib, Michal A. Stanczak, Mauro Corrado, Ramon I. Klein Geltink, Maria Elena Maccari, Matteo Villa, Gustavo E. Carrizo, David E. Sanin, Francesc Baixauli, Beth Kelly, Jonathan D. Curtis, Fabian Haessler, Annette Patterson, Cameron S. Field, George Caputa, Ryan L. Kyle, Melanie Soballa, Minsun Cha, Harry Paul, Jacob Martin, Katarzyna M. Grzes, Lea Flachsmann, Michael Mitterer, Liang Zhao, Frances Winkler, David Ali Rafei-Shamsabadi, Frank Meiss, Bertram Bengsch, Robert Zeiser, Daniel J. Puleston, David O’Sullivan, Edward J. Pearce, Erika L. Pearce
Publikováno v:
Nature Immunology
How lipidome changes support CD8+ effector T (Teff) cell differentiation is not well understood. Here we show that, although naive T cells are rich in polyunsaturated phosphoinositides (PIPn with 3-4 double bonds), Teff cells have unique PIPn marked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bcbbf423f9a7b51630fb44cecc15a8
https://hdl.handle.net/21.11116/0000-000D-12D6-D21.11116/0000-000D-12D8-B
https://hdl.handle.net/21.11116/0000-000D-12D6-D21.11116/0000-000D-12D8-B
Autor:
Nikki van Teijlingen Bakker, Lea Flachsman, Gustavo E. Carrizo, David E. Sanin, Simon Lawless, Angela Castoldi, Lauar Monteiro, Agnieszka M. Kabat, Mai Matsushita, Fabian Haessler, Annette Patterson, Ramon Klein Geltink, David O’Sullivan, Erika L. Pearce, Edward J. Pearce
Fatty acid oxidation (FAO) is upregulated in IL-4-stimulated (alternatively activated) macrophages (M(IL-4)). We examined the effect of loss of function of the enzyme Cpt1a, which facilitates the entry of long chain fatty acids (FA) into mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7dbcd7060184f546ef9d2b7f0881aac
https://doi.org/10.1101/2022.04.13.487890
https://doi.org/10.1101/2022.04.13.487890
Autor:
Erika L. Pearce, Yaarub Musa, Beth Kelly, Thomas Becker, Lea J. Flachsmann, Jonathan D. Curtis, Gustavo E. Carrizo, Gerhard Mittler, David E. Sanin, Chantal Priesnitz, Joy Edwards-Hicks, Joerg M. Buescher, Michal A. Stanczak
Publikováno v:
Nature
The behaviour of Dictyostelium discoideum depends on nutrients1. When sufficient food is present these amoebae exist in a unicellular state, but upon starvation they aggregate into a multicellular organism2,3. This biology makes D. discoideum an idea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c995b0128541268f7ee07e1efbfa16e
https://hdl.handle.net/21.11116/0000-0008-0F63-921.11116/0000-0008-0F65-7
https://hdl.handle.net/21.11116/0000-0008-0F63-921.11116/0000-0008-0F65-7