Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gustavo Della-Flora Nunes"'
Autor:
Gustavo Della-Flora Nunes, Emma R. Wilson, Leandro N. Marziali, Edward Hurley, Nicholas Silvestri, Bin He, Bert W. O’Malley, Bogdan Beirowski, Yannick Poitelon, Lawrence Wrabetz, M. Laura Feltri
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Prohibitin 2 can localize to the axon-Schwann-cell interface and is required for myelin formation. Here, the authors show that deletion of prohibitin 1 in Schwann cells instead triggers severe myelin loss likely caused by mitochondrial dysfunction, a
Externí odkaz:
https://doaj.org/article/dee61ba939654c5b97e3ebabed37e14e
Autor:
Gustavo Della-Flora Nunes, Emma R Wilson, Edward Hurley, Bin He, Bert W O'Malley, Yannick Poitelon, Lawrence Wrabetz, M Laura Feltri
Publikováno v:
eLife, Vol 10 (2021)
Schwann cell (SC) mitochondria are quickly emerging as an important regulator of myelin maintenance in the peripheral nervous system (PNS). However, the mechanisms underlying demyelination in the context of mitochondrial dysfunction in the PNS are in
Externí odkaz:
https://doaj.org/article/bab27ff9a3d44321940e8da7640d677e
Autor:
Júlio Santos-Terra, Iohanna Deckmann, Giovanna Carello-Collar, Gustavo Della-Flora Nunes, Guilherme Bauer-Negrini, Gustavo Brum Schwingel, Mellanie Fontes-Dutra, Rudimar Riesgo, Carmem Gottfried
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4075 (2022)
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized by several alterations, including disorganized brain cytoarchitecture and excitatory/inhibitory (E/I) imbalance. We aimed to analyze aspects associated with the i
Externí odkaz:
https://doaj.org/article/6c86ca47b55a469d98d5b4e1ceb7277c
Autor:
Mauro Mozael Hirsch, Iohanna Deckmann, Mellanie Fontes-Dutra, Guilherme Bauer-Negrini, Gustavo Della-Flora Nunes, Walquiria Nunes, Bruna Rabelo, Rudimar Riesgo, Rogerio Margis, Victorio Bambini-Junior, Carmem Gottfried
Publikováno v:
Data in Brief, Vol 18, Iss , Pp 1433-1440 (2018)
This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavor
Externí odkaz:
https://doaj.org/article/0ab375445a1c4bb0bd6c2715f957a1bb
Autor:
Mellanie Fontes-Dutra, Júlio Santos-Terra, Iohanna Deckmann, Gustavo Brum Schwingel, Gustavo Della-Flora Nunes, Mauro Mozael Hirsch, Guilherme Bauer-Negrini, Rudimar S. Riesgo, Victorio Bambini-Júnior, Cecília Hedin-Pereira, Carmem Gottfried
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Autism spectrum disorder (ASD) is characterized by impairments in both social communication and interaction and repetitive or stereotyped behaviors. Although its etiology remains unknown, genetic and environmental risk factors have been associated wi
Externí odkaz:
https://doaj.org/article/5398c647f6c04f7e9ce3684f0cbd4982
Autor:
Michael R. Weaver, Emma R. Wilson, M. Laura Feltri, Luciana Romina Frick, Gustavo Della-Flora Nunes
Publikováno v:
Dev Neurobiol
Schwann cells play a critical role in the development of the peripheral nervous system, establishing important relationships both with the extracellular milieu and other cell types, particularly neurons. In this review, we discuss various Schwann cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e728d60a97a081dac14733cf61894218
https://doi.org/10.1002/dneu.22744
https://doi.org/10.1002/dneu.22744
Autor:
Diego Baronio, Kamila Castro, Taylor Gonchoroski, Gabriela Mueller de Melo, Gustavo Della Flora Nunes, Victorio Bambini-Junior, Carmem Gottfried, Rudimar Riesgo
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116363 (2015)
Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders primarily characterized by impaired social interaction and communication, and by restricted repetitive behaviors and interests. Ligands of histamine receptor 3 (H3R) are cons
Externí odkaz:
https://doaj.org/article/9488765420ba4857b9709055898e2421
Autor:
Lawrence Wrabetz, Bin He, Bogdan Beirowski, Gustavo Della-Flora Nunes, Leandro N. Marziali, Emma R. Wilson, Bert W. O'Malley, Yannick Poitelon, M. Laura Feltri, Edward Hurley, Nicholas Silvestri
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
In peripheral nerves, Schwann cells form myelin and provide trophic support to axons. We previously showed that the mitochondrial protein prohibitin 2 can localize to the axon-Schwann-cell interface and is required for developmental myelination. Whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c098be287b2f4d181bfdbc5319e4f5
https://doi.org/10.1038/s41467-021-23552-8
https://doi.org/10.1038/s41467-021-23552-8
Autor:
Rudimar dos Santos Riesgo, Victorio Bambini-Junior, Júlio Santos-Terra, Guilherme Bauer-Negrini, Mauro Mozael Hirsch, Walquíria Souza-Nunes, Lily Green, Mellanie Fontes-Dutra, Gustavo Della-Flora Nunes, Carmem Gottfried
Publikováno v:
Behavioural Brain Research. 364:11-18
Impairments in social behaviour are a defining feature of autism spectrum disorder (ASD). Individuals with ASD also usually present some difficulty to recognise or understand another person's feelings. Therefore, it is possible that altered empathy p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b078613aeccb65f2f2e16f2e4ec52fa
https://doi.org/10.1016/j.bbr.2019.01.034
https://doi.org/10.1016/j.bbr.2019.01.034
Autor:
Diego Baronio, Wilson Savino, Rudimar dos Santos Riesgo, Daniella Arêas Mendes-da-Cruz, Gustavo Della-Flora Nunes, Carmem Gottfried, Kamila Castro, Guilherme Bauer-Negrini, Victorio Bambini-Junior
Publikováno v:
Neuroimmunomodulation. 25:280-284
Objective: Considering the potential role of lymphocytes in the pathophysiology of autism spectrum disorder (ASD), we aimed to evaluate possible alterations of T cell pools in the lymphoid organs of an animal model of autism induced by valproic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5e1c4e6a6799dace87326ea62bbea7
https://doi.org/10.1159/000491395
https://doi.org/10.1159/000491395