Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Gustavo Capatti Cassiano"'
Autor:
Gustavo Capatti Cassiano, Axel Martinelli, Melina Mottin, Bruno Junior Neves, Carolina Horta Andrade, Pedro Eduardo Ferreira, Pedro Cravo
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionThe global evolution of resistance to Artemisinin-based Combination Therapies (ACTs) by malaria parasites, will severely undermine our ability to control this devastating disease.MethodsHere, we have used whole genome sequencing to charac
Externí odkaz:
https://doaj.org/article/ce4b8e5c6f0f4e7d8e8946cbdb66c393
Autor:
Adriana F. Gonçalves, Ana Lima-Pinheiro, Miguel Teixeira, Gustavo Capatti Cassiano, Pedro Cravo, Pedro E. Ferreira
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionMalaria parasites increasingly develop resistance to all drugs available in the market, hampering the goal of reducing malaria burden.MethodsHerein, we evaluated the impact of a single-nucleotide variant, E738K, present in the 26S proteas
Externí odkaz:
https://doaj.org/article/660c206067114734948c3e132a0d0834
Autor:
Anyse P. Essoh, Gustavo Capatti Cassiano, Filipa Mandim, Lillian Barros, Isildo Gomes, Márcia Melo Medeiros, Mónica Moura, Pedro Vitor Lemos Cravo, Maria M. Romeiras
Publikováno v:
Plants, Vol 12, Iss 4, p 963 (2023)
Medicinal plants have historically been a source of drugs in multiple applications, including the treatment of malaria infections. The Cabo Verde archipelago harbors a rich diversity of native plants, most of which are used for medicinal purposes. Th
Externí odkaz:
https://doaj.org/article/6229315755864620a627bcf0277aef9b
Autor:
Paula Ferreira Salles, Daiana Souza Perce-da-Silva, Atila Duque Rossi, Luisa Riehl Raposo, Aina Danaisa Ramirez Ramirez, Otílio Machado Pereira Bastos, Lilian Rose Pratt-Riccio, Gustavo Capatti Cassiano, Andrea Regina Souza Baptista, Cynthia Chester Cardoso, Dalma Maria Banic, Ricardo Luiz Dantas Machado
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Genetic variability was linked with individual responses to treatment and susceptibility to malaria by Plasmodium vivax. Polymorphisms in the CYP2D6 gene may modulate enzyme level and activity, thereby affecting individual responses to pharmacologica
Externí odkaz:
https://doaj.org/article/55a584feb85a435b9cab51bc5bacc592
Autor:
Lana Bitencourt Chaves, Daiana de Souza Perce-da-Silva, Rodrigo Nunes Rodrigues-da-Silva, João Hermínio Martins da Silva, Gustavo Capatti Cassiano, Ricardo Luiz Dantas Machado, Lilian Rose Pratt-Riccio, Dalma Maria Banic, Josué da Costa Lima-Junior
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005344 (2017)
The Plasmodium vivax Cell-traversal protein for ookinetes and sporozoites (PvCelTOS) plays an important role in the traversal of host cells. Although essential to PvCelTOS progress as a vaccine candidate, its genetic diversity remains uncharted. Ther
Externí odkaz:
https://doaj.org/article/2f98062867aa42498f1b7364dafa309e
Autor:
Bruno de Paulo Ribeiro, Gustavo Capatti Cassiano, Rodrigo Medeiros de Souza, Dalila Nunes Cysne, Marcos Augusto Grigolin Grisotto, Ana Paula Silva de Azevedo dos Santos, Cláudio Romero Farias Marinho, Ricardo Luiz Dantas Machado, Flávia Raquel Fernandes Nascimento
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 3, p e0004479 (2016)
Mechanisms involved in severe P. vivax malaria remain unclear. Parasite polymorphisms, parasite load and host cytokine profile may influence the course of infection. In this study, we investigated the influence of circumsporozoite protein (CSP) polym
Externí odkaz:
https://doaj.org/article/72cef6db627d4faf8bd995d2c08bf889
Autor:
Adriana Antônia da Cruz Furini, Gustavo Capatti Cassiano, Marcela Petrolini Capobianco, Sidney Emanuel Batista dos Santos, Ricardo Luiz Dantas Machado
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Polymorphisms in cytokine genes can alter the production of these proteins and consequently affect the immune response. The trihybrid heterogeneity of the Brazilian population is characterized as a condition for the use of ancestry informative marker
Externí odkaz:
https://doaj.org/article/652e9095f8404ccf916b416b84daf10e
Autor:
Elenir Alves Macedo de Godoy, Juares Elias Santos Junior, Marcus Vinícius Teresa Belloto, Marcus Vinícius Proença de Moraes, Gustavo Capatti Cassiano, Aline Cardoso Caseca Volotão, Maria Cecília Rui Luvizotto, Claudia Márcia Aparecida Carareto, Mônica Cristina de Moraes Silva, Ricardo Luiz Dantas Machado
Publikováno v:
Microbiology Research, Vol 4, Iss 1, Pp e6-e6 (2013)
In the period from July 2009 to October 2010, fecal samples from 61 animals and 154 humans from the municipality of Aracatuba (São Paulo State, Brazil) were studied. Fecal samples from animals were collected in the Municipal Animal Shelter and the
Externí odkaz:
https://doaj.org/article/72657f9789d64facad74e1cefd5a5e40
Autor:
Margarete do Socorro Mendonça GOMES, José Luiz Fernandes VIEIRA, Gustavo Capatti CASSIANO, Lise MUSSET, Eric LEGRAND, Mathieu NACHER, Vanja Suely Calvosa D'Almeida COUTO, Ricardo Luiz Dantas MACHADO, Álvaro Augusto Ribeiro D'Almeida COUTO
Publikováno v:
Revista do Instituto de Medicina Tropical de São Paulo, Vol 58, Iss 0
SUMMARY Malaria is a major health problem for people who live on the border between Brazil and French Guiana. Here we discuss Plasmodium vivax distribution pattern in the town of Oiapoque, Amapá State using the circumsporozoite (CS) gene as a marker
Externí odkaz:
https://doaj.org/article/02678be6457b49258db7b369c1727f41
Autor:
Lilian Rose Pratt-Riccio, Bárbara de Oliveira Baptista, Vanessa Rodrigues Torres, Cesare Bianco-Junior, Daiana de Souza Perce-Da-Silva, Evelyn Kety Pratt Riccio, Josué da Costa Lima-Junior, Paulo Renato Rivas Totino, Gustavo Capatti Cassiano, Luciane Moreno Storti-Melo, Ricardo Luiz Dantas Machado, Joseli de Oliveira-Ferreira, Dalma Maria Banic, Leonardo José de Moura Carvalho, Cláudio Tadeu Daniel-Ribeiro
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 114
BACKGROUND The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive sequence that is characterised by three variants: VK210, VK247 and P. vivax-like. The most important challenge i
Externí odkaz:
https://doaj.org/article/04c13125146640a684ce6d561efbc37b