Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Gustavo C, Cerqueira"'
Autor:
Laurel A. Keefer, James R. White, Derrick E. Wood, Kelly M. R. Gerding, Kenneth C. Valkenburg, David Riley, Christopher Gault, Eniko Papp, Christine M. Vollmer, Amy Greer, James Hernandez, Paul M. McGregor, Adriana Zingone, Bríd M. Ryan, Kristen Deak, Shannon J. McCall, Michael B. Datto, James L. Prescott, John F. Thompson, Gustavo C. Cerqueira, Siân Jones, John K. Simmons, Abigail McElhinny, Jennifer Dickey, Samuel V. Angiuoli, Luis A. Diaz, Victor E. Velculescu, Mark Sausen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The genomic profiling of tumours has not been widely adopted in the clinic due to technical and practical hurdles. Here, the authors develop PGDx elio tissue complete, a scalable, standardised and FDA-cleared test comprising a targeted gene panel and
Externí odkaz:
https://doaj.org/article/e4aa27119f0a4f1f9ac75c8283f59ea8
Autor:
Gustavo C. Cerqueira, Ian H. Cheeseman, Steve F. Schaffner, Shalini Nair, Marina McDew-White, Aung Pyae Phyo, Elizabeth A. Ashley, Alexandre Melnikov, Peter Rogov, Bruce W. Birren, François Nosten, Timothy J. C. Anderson, Daniel E. Neafsey
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background Artemisinin-based combination therapies are the first line of treatment for Plasmodium falciparum infections worldwide, but artemisinin resistance has risen rapidly in Southeast Asia over the past decade. Mutations in the kelch13
Externí odkaz:
https://doaj.org/article/827f2a0a516745d098ef8cbb6210961b
Autor:
João L Reis-Cunha, Daniella C Bartholomeu, Abigail L Manson, Ashlee M Earl, Gustavo C Cerqueira
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223364 (2019)
BackgroundProphages play a significant role in prokaryotic evolution, often altering the function of the cell that they infect via transfer of new genes e.g., virulence or antibiotic resistance factors, inactivation of existing genes or by modifying
Externí odkaz:
https://doaj.org/article/6512381ea319415a864fe74e22a3c26e
Autor:
Kenneth Wha Eng, Ellen L. Verner, David Wilkes, Kentaro Ohara, Shaham Beg, John K. Simmons, Erika Hissong, Juan Miguel Mosquera, Aanavi Karandikar, Troy Kane, Bishoy Faltas, Kevin Holcomb, Manish A. Shah, Scott T. Tagawa, Eniko Papp, Nasser K. Altorki, Michael Sigouros, Ana M. Molina, Hussein Alnajar, Emily Patchell, Wael Al Zoughbi, Cora N. Sternberg, Murtaza Malbari, Rohan Bareja, Andrea Sboner, Samuel V. Angiuoli, Yariv Houvras, Laurel Keefer, Violeta Beleva Guthrie, Noah Greco, Donna Nichol, David M. Nanus, Daniel Bockelman, Gustavo C. Cerqueira, Olivier Elemento, Jesse Fox, Jyothi Manohar
Publikováno v:
The Oncologist
Background Characterization of circulating tumor DNA (ctDNA) has been integrated into clinical practice. Although labs have standardized validation procedures to develop single locus tests, the efficacy of on‐site plasma‐based next‐generation s
Autor:
Aimee R Taylor, Stephen F Schaffner, Gustavo C Cerqueira, Standwell C Nkhoma, Timothy J C Anderson, Kanlaya Sriprawat, Aung Pyae Phyo, François Nosten, Daniel E Neafsey, Caroline O Buckee
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007065 (2017)
With the rapidly increasing abundance and accessibility of genomic data, there is a growing interest in using population genetic approaches to characterize fine-scale dispersal of organisms, providing insight into biological processes across a broad
Externí odkaz:
https://doaj.org/article/e25b1bd5e1f24caa94c32d02d468b39d
Autor:
Angela M, Early, Flavia, Camponovo, Stéphane, Pelleau, Gustavo C, Cerqueira, Yassamine, Lazrek, Béatrice, Volney, Manuela, Carrasquilla, Benoît, de Thoisy, Caroline O, Buckee, Lauren M, Childs, Lise, Musset, Daniel E, Neafsey
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(30)
Successful infectious disease interventions can result in large reductions in parasite prevalence. Such demographic change has fitness implications for individual parasites and may shift the parasite's optimal life history strategy. Here, we explore
Autor:
Vladimir Gianullin, Leonardo Hagmann, Kevin Arvai, Amira Djebbari, Christopher L. Nobles, Larson Hogstrom, Mael Manesse, Vuna Fa, Fanglei Zhuang, Xi Chen, Viatcheslav E. Katerov, Jorge Garces, Hatim T. Allawi, Abigail McElhinny, Frank Diehl, Gustavo C Cerqueira
Publikováno v:
Cancer Prevention Research. 16:P041-P041
Background: A multi-analyte blood test has the potential to maximize performance for early detection across different cancer stages and types. Improvements in early-stage cancer detection might be achieved using multi-component tests with high sensit
Autor:
Vladimir Gianullin, Leonardo Hagmann, Kevin Arvai, Amira Djebbari, Christopher L. Nobles, Larson Hogstrom, Mael Manesse, Vuna Fa, Fanglei Zhuang, Xi Chen, Viatcheslav E. Katerov, Jorge Garces, Hatim T. Allawi, Abigail McElhinny, Frank Diehl, Gustavo C Cerqueira
Publikováno v:
Cancer Prevention Research. 16:IA023-IA023
Background: A multi-analyte blood test has the potential to maximize performance for early detection across different cancer stages and types. Improvements in early-stage cancer detection might be achieved using multi-component tests with high sensit
Autor:
Gustavo C Cerqueira, Wanderson D DaRocha, Priscila C Campos, Cláudia S Zouain, Santuza MR Teixeira
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 100, Iss 4, Pp 385-389 (2005)
A total of 880 expressed sequence tags (EST) originated from clones randomly selected from a Trypanosoma cruzi amastigote cDNA library have been analyzed. Of these, 40% (355 ESTs) have been identified by similarity to sequences in public databases an
Externí odkaz:
https://doaj.org/article/d3df67858fa74225b64081117f31d477
Autor:
Jonathan Livny, Lorrie L He, Kimberly A. Musser, Jamin Liu, Sophie S. Son, Jill Taylor, Peijun Ma, Milesh M. Patel, Roby P. Bhattacharyya, Lidan Wu, Rui Yang, Nirmalya Bandyopadhyay, Gustavo C. Cerqueira, Alejandro Pironti, Deborah T. Hung, Joseph M. Beechem, Lisa A. Cosimi, Jennifer Skerry, Rich Boykin, Robert F. Rudy, Rustem Khafizov, Ashlee M. Earl, Noam Shoresh, Virginia M. Pierce, Elizabeth Nazarian
Publikováno v:
Nature medicine
Multidrug resistant organisms are a serious threat to human health1,2. Fast, accurate antibiotic susceptibility testing (AST) is a critical need in addressing escalating antibiotic resistance, since delays in identifying multidrug resistant organisms