Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Gustavo, Benaim"'
Autor:
Gustavo Benaim, Alberto Paniz-Mondolfi
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 406 (2024)
Originally developed as a chemotherapeutic agent, miltefosine (hexadecylphosphocholine) is an inhibitor of phosphatidylcholine synthesis with proven antiparasitic effects. It is the only oral drug approved for the treatment of Leishmaniasis and Ameri
Externí odkaz:
https://doaj.org/article/4aeafe2acea64a99bc1494298a2349ed
Autor:
Joyce E. Gutiérrez, Hegira Ramírez, Esteban Fernandez-Moreira, María E. Acosta, Michael R. Mijares, Juan Bautista De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdúch, Liesangerli Labrador-Fagúndez, Bruno G. Stella, Luis José Díaz-Pérez, Gustavo Benaim, Jaime E. Charris
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1709 (2023)
A series of heterocyclic chloroquine hybrids, containing a chain of two carbon atoms at position four of the quinolinic chain and acting as a link between quinoline and several benzoyl groups, is synthesized and screened in vitro as an inhibitor of
Externí odkaz:
https://doaj.org/article/c3ae8e752e514bfdab501d036bed6509
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/4591cbcc6df84ae58e1b4081df5edcc8
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/f74a4f45567747d2914eeb1ebe34f2ea
Autor:
Marianna Stampolaki, Satish R. Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O. Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L. Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M. Shoen, Ioannis P. Papanastasiou, Jose Brea, Michael H. Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I. Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D. Kolocouris
Publikováno v:
ACS Infectious Diseases. 9:342-364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d90461f4e36371da98af3c8fcd49163a
https://doi.org/10.1021/acsinfecdis.2c00537
https://doi.org/10.1021/acsinfecdis.2c00537
Autor:
Génesis Mantilla, María C. Peréz-Gordones, Soledad Cisneros-Montufar, Gustavo Benaim, Juan-Carlos Navarro, Marta Mendoza, José R. Ramírez-Iglesias
Publikováno v:
The Journal of Membrane Biology. 256:159-174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d13a3d932b1f4228ae7ebdf8c22719e
https://doi.org/10.1007/s00232-022-00275-5
https://doi.org/10.1007/s00232-022-00275-5
Publikováno v:
Bio-Protocol, Vol 10, Iss 18 (2020)
Ca2+ is an essential signaling messenger in all eukariotic cells, playing a pivotal role in many cellular functions as cell growth control (differentiation, fertilization and apoptosis), secretion, gene expression, enzyme regulation, among many other
Externí odkaz:
https://doaj.org/article/ee9a80d8fcac426cbd566389132f6e04
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
There is no effective cure for Chagas disease, which is caused by infection with the arthropod-borne parasite, Trypanosoma cruzi. In the search for new drugs to treat Chagas disease, potential therapeutic targets have been identified by exploiting th
Externí odkaz:
https://doaj.org/article/c1a1664a81824a44b8da27dc866453d6
Autor:
Semer Maksoud, Adriana Mayora, Laura Colma, Felipe Sojo, Adriana Pimentel, Vladimir Kouznetsov, Diego Merchán-Arena, Ángel Romero, Francisco Arvelo, Juan Bautista De Sanctis, Gustavo Benaim
Publikováno v:
Investigación Clínica. 63:243-261
Tetrahydroquinoline derivatives are interesting structures exhib-iting a wide range of biological activities, including antitumor effects. In this investigation, the effect of the synthesized tetrahydroquinolines JS-56 and JS-92on apoptosis, intracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea452c5d53c75c751ffde7534eb48569
https://doi.org/10.54817/ic.v63n3a04
https://doi.org/10.54817/ic.v63n3a04
Publikováno v:
Parasitology Research. 121:1761-1773
Trichomonas vaginalis is a protozoan that causes human trichomoniasis, the most common non-viral sexually transmitted infection (STI) affecting approximately 278 million people worldwide. The current treatment for trichomoniasis is based on 1-(2-hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c646335918beb18ce25ec4062699bafd
https://doi.org/10.1007/s00436-022-07521-8
https://doi.org/10.1007/s00436-022-07521-8