Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gustav Graff"'
Autor:
Thomas R. Dean, Gustav Graff, Mark R. Hellberg, Tai-Lee Ke, Peter G. Klimko, Karen S. Haggard
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 19:97-103
Bimatoprost (Lumigan), the ethyl amide derivative of the potent prostaglandin FP agonist 17-phenyl-trinor PGF(2alpha), has been reported to be a member of a pharmacologically unique class of ocular hypotensive agents. To confirm that bimatoprost, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a7e914b5976b441ce74f6459db603a
https://doi.org/10.1089/108076803321637627
https://doi.org/10.1089/108076803321637627
Autor:
Steven T. Miller, Howard L. Brockman, John M. Yanni, Gustav Graff, Maureen M. Momsen, Joshua R. Knudtson
Publikováno v:
Ocular Immunology and Inflammation. 11:247-268
Olopatadine, an effective topical ocular human conjunctival mast cell stabilizer/antihistaminic antiallergic drug, was evaluated and compared to selected classical antihistamines for their interaction with model and natural membranes to ascertain pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8facc164525815f97a6a9741ac8a6ec7
https://doi.org/10.1076/ocii.11.4.247.18261
https://doi.org/10.1076/ocii.11.4.247.18261
Autor:
Lori K. Weimer, Mark R. Hellberg, Karen C. David, Jon C. Nixon, Gustav Graff, Milton T. Brady
Publikováno v:
Inflammation. 27:31-43
Selected ester- (AL-5898 and AL-8417) and amide-linked benzopyran analogues (AL-7538 and AL-12615) were evaluated in vitro for their ability to inhibit key enzymes/processes of the inflammatory response. AL-7538 and AL-12615 exhibited weak intrinsic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::179ae35c7c57807e982558efc70518f7
https://doi.org/10.1023/a:1022687111884
https://doi.org/10.1023/a:1022687111884
Autor:
Sally A. Scheib, William H. Garner, Bruce A. Berkowitz, Gustav Graff, Charles A. Wilson, Mizuto Suzuki
Publikováno v:
Current Eye Research. 23:372-381
Purpose. To compare ocular vascular permeability in the rabbit after vitrectomy as assessed by contrast-enhanced magnetic imaging (CE-MRI) and measurements of aqueous and vitreous humor protein concentration. Methods. Partial vitrectomies were perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e699e406b8958e38f3048967a44f2e5
https://doi.org/10.1076/ceyr.23.5.372.5439
https://doi.org/10.1076/ceyr.23.5.372.5439
Publikováno v:
Acta Ophthalmologica Scandinavica. 78:10-15
Olopatadine is a human conjunctival mast cell stabilizer with antihistaminic activity. Ketotifen is an older molecule that possesses antihistaminic activity and is reported to have additional pharmacological properties. The interactions of these two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cf23e0774d43fdf294ce4197c5ffc3
https://doi.org/10.1034/j.1600-0420.2000.078s230010.x
https://doi.org/10.1034/j.1600-0420.2000.078s230010.x
Publikováno v:
Inflammation. 24:357-370
Nepafenac, the amide analog of 2-amino-3-benzoylbenzeneacetic acid (amfenac), was examined in preclinical models for its potential utility as a topical ocular anti-inflammatory agent. Diclofenac was selected as the reference compound. In contrast to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c98f30c455cd81904d2b5c751aeddd36
https://doi.org/10.1023/a:1007049015148
https://doi.org/10.1023/a:1007049015148
Publikováno v:
Inflammation. 24:371-384
Nepafenac, the amide analog of the NSAID amfenac, was examined in vitro for its bioactivation by ocular tissue components and its ability to permeate external ocular barriers. Rabbit tissues catalyzed a concentration-dependent conversion of nepafenac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a18f33fb0014c843e409a5a6fb17333c
https://doi.org/10.1023/a:1007001131987
https://doi.org/10.1023/a:1007001131987
Autor:
Joan M. Spellman, Gustav Graff, S. Dan Dimitrijevich, Laura Smith Lang, Lori K. Weimer, John M. Yanni, Daniel A. Gamache
Publikováno v:
Ocular Immunology and Inflammation. 5:117-128
The production of cytokines by human conjunctival epithelial cells following stimulation was investigated. Primary cultures of human conjunctival epithelial cells were characterized by morphology and keratin expression. Cultured epithelial cells were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e89b6502805d66561b935d97bd05c1b
https://doi.org/10.3109/09273949709085060
https://doi.org/10.3109/09273949709085060
Autor:
Gustav Graff, Joan M. Spellman, L S Lang, D.W. Parnell, Lori K. Weimer, Steven T. Miller, Milton T. Brady, D.J. Stephens, John M. Yanni, Daniel A. Gamache
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 12:389-400
Olopatadine (AL-4943A; KW-4679) [(z)-11-[3-(dimethylamino)propylidene]-6, 11-dihydrodibenz[b,e]oxepine-2 acetic acid hydrochloride] is an anti-allergic agent which inhibits mast cell mediator release and possesses histamine H1 receptor antagonist act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c11e46a79b5d5a81002e5be8bf4779b
https://doi.org/10.1089/jop.1996.12.389
https://doi.org/10.1089/jop.1996.12.389
Autor:
Joseph C. Nolan, David A. Walsh, L. F. Sancilio, W. J. Jun. Welstead, Gustav Graff, Dwight A. Shamblee, Henry W. Moran
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dc6d9468268fc2770e6540897703663
https://doi.org/10.1002/chin.199105178
https://doi.org/10.1002/chin.199105178