Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans

Autor: Greenhaff Paul L, Gustafsson Thomas, Fischer Helene, Jansson Eva, Timmons James A, Ridden John, Rachman Jonathan, Sundberg Carl

Publikováno v: BMC Biology, Vol 3, Iss 1, p 19 (2005)

Abstract Background Regular exercise reduces cardiovascular and metabolic disease partly through improved aerobic fitness. The determinants of exercise-induced gains in aerobic fitness in humans are not known. We have demonstrated that over 500 genes

Externí odkaz: https://doaj.org/article/e36d5e47a94249ee93423533f43f8585

The rRNA m ⁶ A methyltransferase METTL5 is involved in pluripotency and developmental programs.

Autor: Ignatova VV; Institute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany., Stolz P; Department of Biology II, Human Biology, and BioImaging, Ludwig-Maximilians Universität München, Munich 81377, Germany., Kaiser S; Chemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany., Gustafsson TH; University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA., Lastres PR; Institute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany., Sanz-Moreno A; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Cho YL; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Amarie OV; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Aguilar-Pimentel A; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Klein-Rodewald T; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Calzada-Wack J; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Becker L; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Marschall S; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Kraiger M; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Garrett L; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.; Institute of Developmental Genetics, HMGU, Neuherberg 85764, Germany., Seisenberger C; Institute of Developmental Genetics, HMGU, Neuherberg 85764, Germany., Hölter SM; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.; Institute of Developmental Genetics, HMGU, Neuherberg 85764, Germany., Borland K; Chemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany., Van De Logt E; Chemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany., Jansen PWTC; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, GA Nijmegen 6525, the Netherlands., Baltissen MP; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, GA Nijmegen 6525, the Netherlands., Valenta M; Institute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany., Vermeulen M; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, GA Nijmegen 6525, the Netherlands., Wurst W; Institute of Developmental Genetics, HMGU, Neuherberg 85764, Germany.; Chair of Developmental Genetics, Technische Universität München, Freising-Weihenstephan 85354, Germany.; Deutsches Institut für Neurodegenerative Erkrankungen (DZNE), Munich 81377, Germany.; Munich Cluster for Systems Neurology (SyNergy), Adolf-Butenandt-Institut, Ludwig-Maximilians-Universität München, Munich 81377, Germany., Gailus-Durner V; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Fuchs H; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany., Hrabe de Angelis M; German Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Freising 85354, Germany.; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Rando OJ; University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA., Kellner SM; Chemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany., Bultmann S; Department of Biology II, Human Biology, and BioImaging, Ludwig-Maximilians Universität München, Munich 81377, Germany., Schneider R; Institute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany.; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany.; Faculty of Biology, Ludwig-Maximilians Universität München, Planegg-Martinsried 82152, Germany.

Publikováno v: Genes & development [Genes Dev] 2020 May 01; Vol. 34 (9-10), pp. 715-729. Date of Electronic Publication: 2020 Mar 26.