Výsledky vyhledávání - "Gustaaf P. Van Hees"

Synthesis, chromatographic purification, and analysis of isomers of biliverdin IX and bilirubin IX

Autor: Karel P.M. Heirwegh, Gustaaf P. Van Hees, Norbert Blanckaert

Publikováno v: Analytical Biochemistry. 195:273-278

Neutral solvent systems were developed to isolate the alpha, beta, gamma, and delta isomers of biliverdin IX dimethyl ester by TLC. The individual free acids of biliverdin IX were obtained by saponification of the corresponding dimethyl esters. The b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763244f632a544b557c95005c8caab91
https://doi.org/10.1016/0003-2697(91)90329-r

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Uridine Diphosphate-Glucuronic Acid-independent Conversion of Bilirubin Monoglucuronides to Diglucuronide in Presence of Plasma Membranes from Rat Liver is Nonenzymic

Autor: Gustaaf P. Van Hees, Karel P.M. Heirwegh, Andreas Sieg

Publikováno v: Journal of Clinical Investigation. 69:347-357

TWO ROUTES HAVE BEEN PROPOSED FOR CONVERSION OF BILIRUBIN MONOGLUCURONIDE TO THE DIGLUCURONIDE: glucuronyl transfer (a) from UDP-glucuronic acid to bilirubin monoglucuronide, catalyzed by a microsomal UDP-glucuronyltransferase, and (b) from one molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57a0bf7d51e993f4c91ebad6413357d
https://doi.org/10.1172/jci110458

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Rearranged glucuronic acid conjugates of bilirubin-IXα in post-obstructive bile. Structure elucidation of azopigments β and γ as ethyl anthranilateN-glycosides derived from 2-, 3- and 4-O-acyl glucuronides

Autor: Gustaaf P. Van Hees, Frans Compernolle, Karel P.M. Heirwegh

Publikováno v: Biological Mass Spectrometry. 5:453-459

Azopigment analysis was performed on conjugates of bilirubin-IXalpha in bile of man and rats obtained after obstruction of the bile duct or in bile incubated under N2. The azopigments beta and gamma, formed by applying a pH 2.7 diazonium reagent cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc951ee4099d8cb8707c79fa8cb56fc
https://doi.org/10.1002/bms.1200050707

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Glucuronic acid conjugates of bilirubin-IXα in normal bile compared with post-obstructive bile. Transformation of the 1-O-acylglucuronide into 2-, 3-, and 4-O-acylglucuronides

Autor: Norbert Blanckaert, Gustaaf P. Van Hees, Frans Compernolle, Karel P.M. Heirwegh

Structures have been determined for bilirubin-IXα conjugates in freshly collected bile of normal rats, dogs and man and in post-obstructive bile of man and rats. The originally secreted conjugate has been characterized as azopigment (I), i.e. a 1-O-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14298afa4de4be17f96a13a132b23a3
https://europepmc.org/articles/PMC1184148/

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