Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gustáv Russ"'
Autor:
Ivan Košík, Margaréta Práznovská, Martina Košíková, Zuzana Bobišová, Jaroslav Hollý, Eva Varečková, František Kostolanský, Gustáv Russ
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0118477 (2015)
The aim of the present study was to identify what influences the short half-life of the influenza A virus PB1-F2 protein and whether a prolonged half-life affects the properties of this molecule. We hypothesized that the short half-life of PB1-F2 cou
Externí odkaz:
https://doaj.org/article/340d8a7330ae4d9cb59f95466dad74e4
Defining Influenza A Virus Hemagglutinin Antigenic Drift by Sequential Monoclonal Antibody Selection
Autor:
Jack R. Bennink, Christopher B. Brooke, James S. Gibbs, Gustáv Russ, William L. Ince, Mark G. Delboy, Anju Subba, Scott E. Hensley, Suman R. Das, Jonathan W. Yewdell
Publikováno v:
Cell Host & Microbe. 13(3):314-323
SummaryHuman influenza A virus (IAV) vaccination is limited by “antigenic drift,” rapid antibody-driven escape reflecting amino acid substitutions in the globular domain of hemagglutinin (HA), the viral attachment protein. To better understand dr
Publikováno v:
Leukemia Research. 37:139-145
In this work we focused on analysis of HLA-G5 molecules in the blood of patients with B-CLL leukemia and healthy individuals. Using sandwich ELISA, we found total soluble HLA-G, represented by sHLA-G1 and HLA-G5 in most of B-CLL patients while HLA-G5
Publikováno v:
Archives of Virology. 157:811-817
Although influenza DNA vaccine research has focused mainly on viral hemagglutinin and has led to promising results, other virion proteins have also shown some protective potential. In this work, we explored the potential of a DNA vaccine based on the
Autor:
Jack R. Bennink, Hana Blaškovičová, Jonathan W. Yewdell, Ingrid Krejnusová, Bystrická M, Gustáv Russ, Katarina Polakova, Hana Gocníková
Publikováno v:
Archives of Virology. 154:1599-1604
PB1-F2 is a small influenza A virus (IAV) protein encoded by an alternative (+1) reading frame of the PB1 gene. While dispensable for IAV replication in cultured cells, PB1-F2 has been implicated in IAV pathogenicity. To better understand PB1-F2 expr
Autor:
F Kostolanský, Zuzana Bobišová, J Hollý, Margaréta Práznovská, Gustáv Russ, E. Varečková, Martina Kosikova, Ivan Kosik
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0118477 (2015)
PLoS ONE
PLoS ONE
The aim of the present study was to identify what influences the short half-life of the influenza A virus PB1-F2 protein and whether a prolonged half-life affects the properties of this molecule. We hypothesized that the short half-life of PB1-F2 cou
Autor:
Venkataraman Sriram, Randy R. Brutkiewicz, Gustáv Russ, Katarina Polakova, J. Gourapura Renukaradhya
Publikováno v:
Hybridoma and Hybridomics. 23:373-379
The primary screening of hybridoma clones secreting monoclonal antibodies (MAbs) requires the testing of a large number of hybridoma culture supernatants within a short time and is very labor-intensive. In addition, the type of antigen and its locati
Publikováno v:
Leukemia Research. 27:643-648
It has been suggested that HLA-G antigens may provide tumor cells with an effective immune escape mechanism. So far mostly solid tumors have been analyzed; HLA-G antigen was only exceptionally detected. To further examine HLA-G expression, patients w
Publikováno v:
Microbiology. 81:1727-1735
Monoclonal antibody (MAb) IIB4 displays a rare combination of virus neutralization (VN) activity and broad cross-reactivity with influenza A virus strains of the H3 subtype isolated in a period from 1973 to 1988. The epitope of this antibody has been
Publikováno v:
Virology. 447(1-2)
PB1-F2 is a small influenza A virus (IAV) protein encoded by an alternative reading frame of the PB1 gene. During IAV infection, antibodies to PB1-F2 proteins are induced. To determine their function and contribution to virus infection, three distinc