Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Gus A Wright"'
Autor:
Ji Yeon Noh, Hye Won Han, Da Mi Kim, Erin D. Giles, Yuhua Z. Farnell, Gus A. Wright, Yuxiang Sun
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Chronic low-grade inflammation is a hallmark of aging, aka “inflammaging”, which is linked to a wide range of age-associated diseases. Immune dysfunction increases disease susceptibility, and increases morbidity and mortality of aging. Innate imm
Externí odkaz:
https://doaj.org/article/9361aa82ed5f4bdaae8829f6e0b2fe9b
Autor:
Broderick Dickerson, Drew E. Gonzalez, Ryan Sowinski, Dante Xing, Megan Leonard, Jacob Kendra, Victoria Jenkins, Siddharth Gopalakrishnan, Choongsung Yoo, Joungbo Ko, Syamkumar Sivasankara Pillai, Jigna R. Bhamore, Bhimanagouda S. Patil, Gus A. Wright, Christopher J. Rasmussen, Richard B. Kreider
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3358 (2024)
Background: Previous trials have displayed augmented intracellular vitamin C concentrations in the leukocytes at 24 h after acute supplementation with 1000 mg calcium ascorbate (CA), compared to ascorbic acid (AA). Objective: The primary objective wa
Externí odkaz:
https://doaj.org/article/73096e73c5e546e2b1141e3cbb307d17
Autor:
Nicholas L. Drury, Toriq Mustapha, Ross A. Shore, Jiayun Zhao, Gus A. Wright, Aline Rodrigues Hoffmann, Susanne U. Talcott, Annette Regan, Robert M. Tighe, Renyi Zhang, Natalie M. Johnson
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background Interactions between air pollution and infectious agents are increasingly recognized and critical to identify, especially to protect vulnerable populations. Pregnancy represents a vulnerable period for influenza infection and air
Externí odkaz:
https://doaj.org/article/cb046ea972994521a1b861f9c86f1fc6
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Piperlongumine and derivatives are being developed as anticancer agents which act primarily as inducers of reactive oxygen species (ROS) in cancer cell lines. Many of the anticancer activities of piperlongumine resemble those observed for bis-indole
Externí odkaz:
https://doaj.org/article/ef078db5186846df887b22b853632a10
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-14 (2019)
Abstract Background The promise of biopharmaceuticals comprising one or more binding domains motivates the development of novel methods for de novo isolation and affinity maturation of virion-binding domains. Identifying avenues for overcoming the ch
Externí odkaz:
https://doaj.org/article/8a285cc7d440451697a7eacd573c5aed
Autor:
Carmen H. Lau, Drew Pendleton, Nicholas L. Drury, Jiayun Zhao, Yixin Li, Renyi Zhang, Gus A. Wright, Aline Rodrigues Hoffmann, Natalie M. Johnson
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 202 (2022)
Early life exposure to particulate matter (PM) air pollution negatively impacts neonatal health. The underlying mechanisms following prenatal exposure, particularly to ultrafine particles (UFP, diameter ≤ 0.1 μm), are not fully understood; To eval
Externí odkaz:
https://doaj.org/article/3bedae2dd2a848a6862637bdc79fd3c9
Publikováno v:
Exp Biol Med (Maywood)
The orexigenic hormone ghrelin and its receptor, growth hormone secretagogue receptor (GHS-R), have been extensively studied in the last two decades, revealing that ghrelin signaling has important implications in health and disease. Metabolic disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a0d45be3996519286af535a9075da1
https://doi.org/10.1177/15353702221121635
https://doi.org/10.1177/15353702221121635
Autor:
Mark F. Richardson, Kylie Munyard, Larry J. Croft, Theodore R. Allnutt, Felicity Jackling, Fahad Alshanbari, Matthew Jevit, Gus A. Wright, Rhys Cransberg, Ahmed Tibary, Polina Perelman, Belinda Appleton, Terje Raudsepp
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The development of high-quality chromosomally assigned reference genomes constitutes a key feature for understanding genome architecture of a species and is critical for the discovery of the genetic blueprints of traits of biological significance. So
Externí odkaz:
https://doaj.org/article/aca2ab7a2a5744c4bcd266de4e3250a0
PD-L1 is expressed in tumor cells and its interaction with PD-1 plays an important role in evading immune surveillance; this can be overcome using PD-L1 or PD-1 immunotherapy antibodies. This study reports a novel approach for targeting PD-L1. In hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9f4a77ddcfe32eb60f83714d6995a9
https://doi.org/10.1158/0008-5472.c.6512221
https://doi.org/10.1158/0008-5472.c.6512221
Supplemental Figure S4. NR4A1 antagonist inhibit 4T1-luc cell growth and invasion, and induce apoptosis. 4T1-Luc cells were treated with different concentrations of CDIM8 or Cl-OCH3 and effects on cell proliferation (A), invasion (B) and induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a99ab4fbc55636b9f1eadae6ae8e07
https://doi.org/10.1158/0008-5472.22426087.v1
https://doi.org/10.1158/0008-5472.22426087.v1