Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gururaj Shivange"'
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The COVID-19 causing coronavirus (SARS-CoV-2) remains a public health threat worldwide. SARS-CoV-2 enters human lung cells via its spike glycoprotein binding to angiotensin-converting enzyme 2 (ACE2). Notably, the cleavage of the spike by th
Externí odkaz:
https://doaj.org/article/4b92d1c9200d40f0b59f2b49a1936380
Autor:
Gururaj Shivange, Tanmoy Mondal, Evan Lyerly, Sanchita Bhatnagar, Charles N. Landen, Shivani Reddy, Jonathan Kim, Britney Doan, Paula Riddle, Jogender Tushir-Singh
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109953- (2021)
Summary: Receptor clustering is the first and critical step to activate apoptosis by death receptor-5 (DR5). The recent discovery of the autoinhibitory DR5 ectodomain has challenged the long-standing view of its mechanistic activation by the natural
Externí odkaz:
https://doaj.org/article/60c0e8c51e324df1a195182838329e2c
Autor:
Sanchita Bhatnagar, Jogender Tushir-Singh, Jacqueline Lehmann-Che, Luis Teixeira, Marty W. Mayo, Benjamin B. Morris, Kun Xing, Chandrajeet Singh, Ilyas Saltani, Gururaj Shivange, Caroline Conlan, Tanmoy Mondal, Rachisan Djiake Tihagam, Song Lou, Piotr Przanowski
The majority of clinical deaths in patients with triple-negative breast cancer (TNBC) are due to chemoresistance and aggressive metastases, with high prevalence in younger women of African ethnicity. Although tumorigenic drivers are numerous and vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::891142c307609ce415358eb3c23e4c65
https://doi.org/10.1158/0008-5472.c.6512620.v1
https://doi.org/10.1158/0008-5472.c.6512620.v1
Autor:
Sanchita Bhatnagar, Jogender Tushir-Singh, Jacqueline Lehmann-Che, Luis Teixeira, Marty W. Mayo, Benjamin B. Morris, Kun Xing, Chandrajeet Singh, Ilyas Saltani, Gururaj Shivange, Caroline Conlan, Tanmoy Mondal, Rachisan Djiake Tihagam, Song Lou, Piotr Przanowski
Table I: List of TRIM37-associated DSB repair and cell proliferation genes expressed in non-TNBC, TNBC and normal tissue obtained from METABRIC patient cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5dc02dbf4729d5f85453ca51cf1589
https://doi.org/10.1158/0008-5472.22427305
https://doi.org/10.1158/0008-5472.22427305
Autor:
Sanchita Bhatnagar, Jogender Tushir-Singh, Jacqueline Lehmann-Che, Luis Teixeira, Marty W. Mayo, Benjamin B. Morris, Kun Xing, Chandrajeet Singh, Ilyas Saltani, Gururaj Shivange, Caroline Conlan, Tanmoy Mondal, Rachisan Djiake Tihagam, Song Lou, Piotr Przanowski
Supplementary Figure 4. Chemotherapy activates ATM/E2F1/STAT axis to upregulate TRIM37 in TNBC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47570e9fb26ce0ab33ef631f3834006f
https://doi.org/10.1158/0008-5472.22427341.v1
https://doi.org/10.1158/0008-5472.22427341.v1
Autor:
Sanchita Bhatnagar, Jogender Tushir-Singh, Jacqueline Lehmann-Che, Luis Teixeira, Marty W. Mayo, Benjamin B. Morris, Kun Xing, Chandrajeet Singh, Ilyas Saltani, Gururaj Shivange, Caroline Conlan, Tanmoy Mondal, Rachisan Djiake Tihagam, Song Lou, Piotr Przanowski
Supplementary Methods and Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8871639e75c65f2ba7a9f291aa8ab2
https://doi.org/10.1158/0008-5472.22427326
https://doi.org/10.1158/0008-5472.22427326
Autor:
Rachisan Gabriel Djiake Tihagam, Tanmoy Mondal, Ilyas Saltani, Chandrajeet Singh, Benjamin B. Morris, Caroline Conlan, Luis Augusto Teixeira, Jacqueline Lehmann-Che, Gururaj Shivange, Marty W. Mayo, Sanchita Bhatnagar, Jogender Tushir-Singh, Piotr Przanowski, Kun Xing, Song Lou
Publikováno v:
Cancer Res
Cancer research, vol 80, iss 21
Cancer research, vol 80, iss 21
The majority of clinical deaths in patients with triple-negative breast cancer (TNBC) are due to chemoresistance and aggressive metastases, with high prevalence in younger women of African ethnicity. Although tumorigenic drivers are numerous and vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b483bf2023213c4eaa5ef4787a9c81c
https://doi.org/10.1158/0008-5472.can-20-1459
https://doi.org/10.1158/0008-5472.can-20-1459
The novel and highly pathogenic coronavirus (SARS-CoV-2) remains a public health threat worldwide. SARS-CoV-2 enters human host lung cells via its spike protein binding to angiotensin-converting enzyme 2 (ACE2) in a process critical dependent on host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a2e2c779b9a96ad7709c5beb745080b
https://doi.org/10.1101/2021.03.11.434589
https://doi.org/10.1101/2021.03.11.434589
Autor:
Roxanna Mosavian, J. Chuck Harrell, Michael Battista, M Sharon Stack, Sanchita Bhatnagar, Jogender Tushir-Singh, Rachisan Gt Tihagam, Paula D Bos, Evan Lyerly, Narmeen S. Rashid, Divpriya Talwar, Edward B. Stelow, Karol Urbanek, Tanmoy Mondal, Gururaj Shivange
Publikováno v:
EMBO molecular medicine, vol 13, iss 3
EMBO Molecular Medicine, Vol 13, Iss 3, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 3, Pp n/a-n/a (2021)
EMBO Molecular Medicine
Lack of effective immune infiltration represents a significant barrier to immunotherapy in solid tumors. Thus, solid tumor‐enriched death receptor‐5 (DR5) activating antibodies, which generates tumor debulking by extrinsic apoptotic cytotoxicity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6abe71cd79e53b533dc00b47a4172a4
https://escholarship.org/uc/item/1x36b8bh
https://escholarship.org/uc/item/1x36b8bh
Publikováno v:
Journal of Visualized Experiments.
Monoclonal antibodies are high affinity multifunctional drugs that work by variable independent mechanisms to eliminate cancer cells. Over the last few decades, the field of antibody-drug conjugates, bispecific antibodies, chimeric antigen receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1216d3aa986157540b309d6f695869b8
https://doi.org/10.3791/60727
https://doi.org/10.3791/60727