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Autor:
Puralae Channabasavaiah Jagadish, Prajakta Harish Patil, Fajeelath Fatima, Sumit Birangal, Gurupur Gautham Shenoy, Mahadev Rao, Junaid Farooqui, Himanshu Rastogi, Tarun Sharma, Jakir Pinjari
Publikováno v:
Current Drug Metabolism. 23:137-149
Background and objective: Concurrent usage of proton pump inhibitors and their effect on survival and medication termination has been found in individuals receiving protein kinase inhibitor chemotherapy. To investigate the drug-drug interaction mecha
Autor:
Subham Das, Angel Treasa Alex, Alex Joseph, Anu Kunnath Ramachandran, Jayesh Mudgal, Gurupur Gautham Shenoy
Publikováno v:
Current Neuropharmacology
Alzheimer’s disease (AD) is a complex neurodegenerative disease that leads to insidious deterioration of brain functions and is considered the sixth leading cause of death in the world. Alzheimer’s patients suffer from memory loss, cognitive defi
Publikováno v:
CNSneurological disorders drug targets.
Abstract: COVID-19, which primarily affects the pulmonary system, turned out to be a global pandemic, whereas the effects on other systems are still unknown. SARS-CoV-2, binds to angiotensin-converting enzyme 2 (ACE2) receptors in the lungs, causing
Autor:
Prajakta Harish Patil, Mrunal Desai, Rajat Radhakrishna Rao, Srinivas Mutalik, Gurupur Gautham Shenoy, Mahadev Rao, Puralae Channabasavaiah Jagadish
Publikováno v:
Journal of Applied Pharmaceutical Science.
Autor:
Varadaraj Bhat Giliyar, Pritesh Bhat, Amol B. Khade, Mradul Tiwari, Vandana Kalwaje Eshwara, Sidhartha S Kar, Cinu T Alummoottil, Gurupur Gautham Shenoy, Ashutosh Prasad Tiwari
Publikováno v:
Medicinal Chemistry. 16:256-270
Background: The well-known antibacterial agent Triclosan (TCL) that targets bacterial enoylacyl protein reductase has been described to inhibit human fatty acid synthase (FASN) via the enoylacyl reductase domain. A Literature survey indicates that TC