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Akademický článek

Simultaneous Estimation of Quercetin and trans-Resveratrol in Cissus quadrangularis Extract in Rat Serum Using Validated LC-MS/MS Method: Application to Pharmacokinetic and Stability Studies

Autor: Shailesh D. Dadge, Anees A. Syed, Athar Husain, Guru R. Valicherla, Jiaur R. Gayen

Publikováno v: Molecules, Vol 28, Iss 12, p 4656 (2023)

Cissus quadrangularis is a nutrient-rich plant with a history of use in traditional medicine. It boasts a diverse range of polyphenols, including quercetin, resveratrol, β-sitosterol, myricetin, and other compounds. We developed and validated a sens

Externí odkaz: https://doaj.org/article/2c54c38b42b84697b21d035c37fdef89

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Small Object Detection for Indoor Assistance to the Blind using YOLO NAS Small and Super Gradients

Autor: BN, Rashmi, Guru, R., A, Anusuya M

Advancements in object detection algorithms have opened new avenues for assistive technologies that cater to the needs of visually impaired individuals. This paper presents a novel approach for indoor assistance to the blind by addressing the challen

Externí odkaz: http://arxiv.org/abs/2409.07469

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Akademický článek

Which obesity index is a better predictor for cardiometabolic risk factors in a young adult rural population of Telangana State, India?

Autor: G N Kusneniwar, Guru R Jammy, D Shailendra, C H Bunker, P S Reddy

Publikováno v: Journal of Family Medicine and Primary Care, Vol 9, Iss 9, Pp 4667-4672 (2020)

Background: Waist-to-height ratio (WHtR) has recently been found to be a useful marker of cardiovascular disease (CVD) risk in populations in developed countries; the comparison of various obesity indices, particularly WHtR, has received little study

Externí odkaz: https://doaj.org/article/3cb94857d9b04dc1bbe69767574deb58

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Akademický článek

Transport and Permeation Properties of Dapivirine: Understanding Potential Drug-Drug Interactions

Autor: Ruohui Zheng, Guru R. Valicherla, Junmei Zhang, Jeremy Nuttall, Peter Silvera, Leslie J. Marshall, Philip E. Empey, Lisa C. Rohan

Publikováno v: Pharmaceutics, Vol 14, Iss 9, p 1948 (2022)

The dapivirine (DPV) vaginal ring was developed by the nonprofit International Partnership for Microbicides (IPM) for reducing the risk of HIV infection. A clinical study (IPM 028) showed that concomitant use of the DPV ring and miconazole (MIC) alte

Externí odkaz: https://doaj.org/article/e4fb5b9b7a494d1bbd074a70a13b599f

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Akademický článek

Evaluation of the Pharmacokinetics of the Pancreastatin Inhibitor PSTi8 Peptide in Rats: Integration of In Vitro and In Vivo Findings

Autor: Guru R. Valicherla, Roshan A. Katekar, Shailesh Dadge, Mohammed Riyazuddin, Anees A. Syed, Sandeep K. Singh, Athar Husain, Muhammad Wahajuddin, Jiaur R. Gayen

Publikováno v: Molecules, Vol 27, Iss 2, p 339 (2022)

PSTi8 is a pancreastatin inhibitory peptide that is effective in the treatment of diabetic models. This study investigates the pharmacokinetic (PK) properties of PSTi8 in Sprague Dawley rats, for the first time. In vitro and in vivo PK studies were p

Externí odkaz: https://doaj.org/article/a9f35fbe670f4dcaac4e4772f67a0b4e

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