Self-Boosting Programmable Release of Multiple Therapeutic Agents by Activatable Heterodimeric Prodrug-Enzyme Assembly for Antitumor Therapy.

Autor: Jiang S; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China.; Nanophotonics Research Center, Shenzhen Key Laboratory of Micro-Scale Optical Information Technology, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen, 518060, China., Gurram B; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China.; Department of BioInterfaces, Institute for Chemistry and Bioanalytics, School of Life Sciences, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, 4132, Switzerland., Zhu J; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China., Lei S; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China., Zhang Y; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China., He T; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China., Tagit O; Department of BioInterfaces, Institute for Chemistry and Bioanalytics, School of Life Sciences, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, 4132, Switzerland., Fang H; Nanophotonics Research Center, Shenzhen Key Laboratory of Micro-Scale Optical Information Technology, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen, 518060, China., Huang P; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China., Lin J; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov 21, pp. e2409960. Date of Electronic Publication: 2024 Nov 21.

Chromosomal numeric aberrations and rare copy number variation in patients with inflammatory bowel disease

Autor: Dirvanskyte, P, Gurram, B, Bolton, C, Warner, N, Jones, KDJ, Griffin, HR, Park, JY, Keller, K-M, Gilmour, KC, Hambleton, S, Muise, AM, Wysocki, C, Uhlig, HH

Publikováno v: Journal of Crohn'scolitis.

Background and AimsInflammatory bowel diseases [IBD] have a complex polygenic aetiology. Rare genetic variants can cause monogenic intestinal inflammation. The impact of chromosomal aberrations and large structural abnormalities on IBD susceptibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de367e1c6544d1f65a3fc4865561a2d2
https://pubmed.ncbi.nlm.nih.gov/35907265

Chromosomal Numerical Aberrations and Rare Copy Number Variation in Patients with Inflammatory Bowel Disease.

Autor: Dirvanskyte P; Translational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Gurram B; Department of Pediatrics, UT Southwestern Medical Center, Dallas TX, USA., Bolton C; Institute of Child Health, University College London, London, UK.; Paediatric Gastroenterology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Warner N; SickKids Inflammatory Bowel Disease Centre, Hospital for Sick Children, Toronto, ON, Canada., Jones KDJ; Paediatric Gastroenterology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Griffin HR; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Park JY; Department of Pathology and the Eugene McDermott Center for Human Growth and Development. UT Southwestern Medical Center, Dallas, TX, USA., Keller KM; German Clinic for Diagnostics [DKD], Helios Klinik, Wiesbaden, Germany., Gilmour KC; Laboratory of Immunology and Cellular Therapy, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK., Hambleton S; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Muise AM; SickKids Inflammatory Bowel Disease Centre, Hospital for Sick Children, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.; Cell Biology Program, Sick Kids Research Institute, Hospital for Sick Children, Toronto, ON, Canada.; Department of Pediatrics, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Wysocki C; Department of Pediatrics, and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Uhlig HH; Translational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Paediatrics, John Radcliffe Hospital, Oxford, UK.

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2023 Jan 27; Vol. 17 (1), pp. 49-60.

Plasmon-Accelerated Generation of Singlet Oxygen on an Au/MoS 2 Nanohybrid for Enhanced Photodynamic Killing of Bacterial Pathogens/Cancerous Cells.

Autor: Younis MR; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China.; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China., An R; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China., Wang Y; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China., He G; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China., Gurram B; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China.; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China., Wang S; Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China., Lin J; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China., Ye D; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China., Huang P; Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China., Xia XH; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.

Publikováno v: ACS applied bio materials [ACS Appl Bio Mater] 2022 Feb 21; Vol. 5 (2), pp. 747-760. Date of Electronic Publication: 2022 Jan 18.

Pediatric autoimmune gastritis: clinical correlates and histologic features.

Autor: Kulak O; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, United States. Electronic address: Ozlem.kulak@phhs.org., Gurram B; Division of Pediatric Gastroenterology, UT Southwestern Medical Center and Children's Medical Center Dallas, Dallas, TX 75235, United States. Electronic address: Bhaskar.gurram@utsouthwestern.edu., Montgomery EA; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33101, United States. Electronic address: Eam305@med.miami.edu., Park JY; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, United States; Eugene McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX 75235, United States; Department of Pathology and Laboratory Medicine, Children's Medical Center of Dallas, Dallas, TX 75235, United States. Electronic address: jaspar@childrens.com.

Publikováno v: Human pathology [Hum Pathol] 2021 Oct; Vol. 116, pp. 31-38. Date of Electronic Publication: 2021 Jul 18.