Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Guro Elisabeth Lind"'
Publikováno v:
JHEP Reports, Vol 2, Iss 5, Pp 100143- (2020)
Summary: Cholangiocarcinoma (CCA) is a highly fatal malignancy of the bile ducts that arises in up to 20% of patients with primary sclerosing cholangitis (PSC). Current detection methods for CCA display suboptimal sensitivity and/or specificity, and
Externí odkaz:
https://doaj.org/article/f855bbd15e2f48aa8e655a7cdbd3650a
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2657 (2019)
Changes in DNA methylation have been causally linked with cancer and provide promising biomarkers for detection in biological fluids such as blood, urine, and saliva. The field has been fueled by genome-wide characterization of DNA methylation across
Externí odkaz:
https://doaj.org/article/6d2dcee1600f4630a0900fb93a0a0be5
Autor:
Heidi Dietrichson Pharo, Marine Jeanmougin, Eirill Ager-Wick, Hege Marie Vedeld, Anne Klara Sørbø, Christina Dahl, Louise Katrine Larsen, Hilde Honne, Sara Brandt-Winge, May-Britt Five, Sara Monteiro-Reis, Rui Henrique, Carmen Jeronimo, Kenneth Steven, Rolf Wahlqvist, Per Guldberg, Guro Elisabeth Lind
Publikováno v:
Clinical epigenetics. 14(1)
Background Cystoscopy is the gold standard for bladder cancer detection, but is costly, invasive and has imperfect diagnostic accuracy. We aimed to identify novel and accurate DNA methylation biomarkers for non-invasive detection of bladder cancer in
Autor:
Marine Jeanmougin, Hans Petter Brodal, Heidi Dietrichson Pharo, Hege Marie Vedeld, Guro Elisabeth Lind
Publikováno v:
Bioinformatics (Oxford, England).
Motivation Droplet digital PCR (ddPCR) holds great promises for investigating DNA methylation with high sensitivity. Yet, the lack of methods for analyzing ddPCR DNA methylation data has resulted in users processing the data manually at the expense o
Autor:
Sverre Heim, Torstein R. Meling, Anita Sveen, Lina Cekaite, Petter Brandal, Marine Jeanmougin, Ragnhild A. Lothe, David Scheie, Annette Bentsen Håvik, Guro Elisabeth Lind, Trude H. Ågesen
Publikováno v:
Molecular Oncology
Jeanmougin, M, Håvik, A B, Cekaite, L, Brandal, P, Sveen, A, Meling, T R, Ågesen, T H, Scheie, D, Heim, S, Lothe, R A & Lind, G E 2020, ' Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment ', Molecular Oncology, vol. 14, no. 5, pp. 1016-1027 . https://doi.org/10.1002/1878-0261.12668
Molecular Oncology, Vol 14, Iss 5, Pp 1016-1027 (2020)
Molecular Oncology, Vol. 14, No 5 (2020) pp. 1016-1027
Jeanmougin, M, Håvik, A B, Cekaite, L, Brandal, P, Sveen, A, Meling, T R, Ågesen, T H, Scheie, D, Heim, S, Lothe, R A & Lind, G E 2020, ' Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment ', Molecular Oncology, vol. 14, no. 5, pp. 1016-1027 . https://doi.org/10.1002/1878-0261.12668
Molecular Oncology, Vol 14, Iss 5, Pp 1016-1027 (2020)
Molecular Oncology, Vol. 14, No 5 (2020) pp. 1016-1027
Glioblastoma (GBM), the most aggressive form of brain cancer, is characterized by a high level of molecular heterogeneity, and infiltration by various immune and stromal cell populations. Important advances have been made in deciphering the microenvi
Autor:
Tom H. Karlsen, Guro Elisabeth Lind, Hege Marie Vedeld, Erik von Seth, Vemund Paulsen, Martti Färkkilä, Kim Andresen, Hilde Honne, Heidi D. Pharo, Kirsten Muri Boberg, Annika Bergquist, Marine Jeanmougin, Marit Mæhle Grimsrud, Trine Folseraas, Lars Aabakken
Background and Aims Primary sclerosing cholangitis (PSC) is associated with increased risk of cholangiocarcinoma (CCA). Early and accurate CCA detection represents an unmet clinical need as the majority of patients with PSC are diagnosed at an advanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4203012bc540f668fae458e91e23bd7a
http://hdl.handle.net/10138/338041
http://hdl.handle.net/10138/338041
Autor:
Guro Elisabeth Lind, Jonas Langerud, Bjørnar Tovson Bae Flatin, Rita Pinto, Marine Jeanmougin, Hege Marie Vedeld, Ragnhild A. Lothe, Anita Sveen
Publikováno v:
International Journal of Cancer
Intratumor heterogeneity of colorectal cancers (CRCs) is manifested both at the genomic and epigenomic levels. Early genetic aberrations in carcinogenesis are clonal and present throughout the tumors, but less is known about the heterogeneity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed527a247b7b33ee36c55b1653208a2f
http://hdl.handle.net/10852/82751
http://hdl.handle.net/10852/82751
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-4 (2018)
We have previously shown that aberrant promoter methylation of ZNF331 is a potential biomarker for colorectal cancer detection with high sensitivity (71%) and specificity (98%). This finding was recently confirmed by others, and it was additionally s
Autor:
Ole H. Sjo, Marine Jeanmougin, Gro Kummeneje Presthus, Hilde Honne, Merete Hektoen, Mette Eknæs, Hege Marie Vedeld, Ragnhild A. Lothe, Stine A. Danielsen, Marianne Aarstad Merok, Guro Elisabeth Lind, Aud Svindland, Arild Nesbakken
Publikováno v:
International Journal of Cancer. 141:967-976
The prognostic value of CpG island methylator phenotype (CIMP) in colorectal cancer remains unsettled. We aimed to assess the prognostic value of this phenotype analyzing a total of 1126 tumor samples obtained from two Norwegian consecutive colorecta
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2657 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Changes in DNA methylation have been causally linked with cancer and provide promising biomarkers for detection in biological fluids such as blood, urine, and saliva. The field has been fueled by genome-wide characterization of DNA methylation across