Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Guro E. Lind"'
Autor:
Stine H. Kresse, Sara Brandt-Winge, Heidi Pharo, Bjørnar T. B. Flatin, Marine Jeanmougin, Hege Marie Vedeld, Guro E. Lind
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background DNA methylation biomarkers in circulating cell-free DNA (cfDNA) have great clinical potential for cancer management. Most methods for DNA methylation analysis require bisulfite conversion, causing DNA degradation and loss. This is
Externí odkaz:
https://doaj.org/article/3533e452970e4e5a9487c7ab1707a11a
Autor:
Heidi M. Namløs, Magne Skårn, Deeqa Ahmed, Iwona Grad, Kim Andresen, Stine H. Kresse, Else Munthe, Massimo Serra, Katia Scotlandi, Antonio Llombart-Bosch, Ola Myklebost, Guro E. Lind, Leonardo A. Meza-Zepeda
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Osteosarcoma is the most common primary malignant tumour of bone occurring in children and young adolescents and is characterised by complex genetic and epigenetic changes. The miRNA miR-486-5p has been shown to be downregulated i
Externí odkaz:
https://doaj.org/article/b508152fbe6b4d9db3a0cc3f2bf17690
Autor:
Marine Jeanmougin, Annette B. Håvik, Lina Cekaite, Petter Brandal, Anita Sveen, Torstein R. Meling, Trude H. Ågesen, David Scheie, Sverre Heim, Ragnhild A. Lothe, Guro E. Lind
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1016-1027 (2020)
Glioblastoma (GBM), the most aggressive form of brain cancer, is characterized by a high level of molecular heterogeneity, and infiltration by various immune and stromal cell populations. Important advances have been made in deciphering the microenvi
Externí odkaz:
https://doaj.org/article/50f176e97628490093af05af0a6840dd
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-4 (2018)
Abstract We have previously shown that aberrant promoter methylation of ZNF331 is a potential biomarker for colorectal cancer detection with high sensitivity (71%) and specificity (98%). This finding was recently confirmed by others, and it was addit
Externí odkaz:
https://doaj.org/article/2d5d6a5262e748b1967fe6a5c5759427
Autor:
Heidi D. Pharo, Kim Andresen, Kaja C. G. Berg, Ragnhild A. Lothe, Marine Jeanmougin, Guro E. Lind
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation. For increased precision of the methylation analysis, we aimed to develop a robus
Externí odkaz:
https://doaj.org/article/7d294ef663de45ae8e0b794de3531886
Autor:
Guro E. Lind, Marianne Guriby, Terje Ahlquist, Israr Hussain, Marine Jeanmougin, Kjetil Søreide, Hartwig Kørner, Ragnhild A. Lothe, Oddmund Nordgård
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-8 (2017)
Abstract Background Patients with early colorectal cancer (stages I–II) generally have a good prognosis, but a subgroup of 15–20% experiences relapse and eventually die of disease. Occult metastases have been suggested as a marker for increased r
Externí odkaz:
https://doaj.org/article/08a534a705a04ef3ae86ef57bfc08c4e
Autor:
Kaja C. G. Berg, Peter W. Eide, Ina A. Eilertsen, Bjarne Johannessen, Jarle Bruun, Stine A. Danielsen, Merete Bjørnslett, Leonardo A. Meza-Zepeda, Mette Eknæs, Guro E. Lind, Ola Myklebost, Rolf I. Skotheim, Anita Sveen, Ragnhild A. Lothe
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-16 (2017)
Abstract Background Colorectal cancer (CRC) cell lines are widely used pre-clinical model systems. Comprehensive insights into their molecular characteristics may improve model selection for biomedical studies. Methods We have performed DNA, RNA and
Externí odkaz:
https://doaj.org/article/1c36a9590cb44924a770ed1579d70e77
Autor:
Anita Sveen, Bjarne Johannessen, Torstein Tengs, Stine A. Danielsen, Ina A. Eilertsen, Guro E. Lind, Kaja C. G. Berg, Edward Leithe, Leonardo A. Meza-Zepeda, Enric Domingo, Ola Myklebost, David Kerr, Ian Tomlinson, Arild Nesbakken, Rolf I. Skotheim, Ragnhild A. Lothe
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-16 (2017)
Abstract Background Approximately 15% of primary colorectal cancers have DNA mismatch repair deficiency, causing a complex genome with thousands of small mutations—the microsatellite instability (MSI) phenotype. We investigated molecular heterogene
Externí odkaz:
https://doaj.org/article/8f0e1d213c3d4e3598c8467bea896b89
Autor:
Lina Cekaite, Juha K. Rantala, Jarle Bruun, Marianne Guriby, Trude H. Ågesen, Stine A. Danielsen, Guro E. Lind, Arild Nesbakken, Olli Kallioniemi, Ragnhild A. Lothe, Rolf I. Skotheim
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 9, Pp 868-879 (2012)
Several microRNAs (miRNAs) are known to be deregulated in colon cancer, but the mechanisms behind their potential involvement on proliferation and tumor cell survival are unclear. The present study aimed to identify miRNAs with functional implication
Externí odkaz:
https://doaj.org/article/fec7c093a2f84e6cafaa0c5f14d3aa5b
Autor:
Terje Ahlquist, Irene Bottillo, Stine A. Danielsen, Gunn I. Meling, Torleiv O. Rognum, Guro E. Lind, Bruno Dallapiccola, Ragnhild A. Lothe
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 7, Pp 680-686 (2008)
More than half of all colorectal carcinomas are known to exhibit an activated mitogen-activated protein kinase pathway. The NF1 gene, a negative regulator of KRAS, has not previously been examined in a series of colorectal cancer. In the present stud
Externí odkaz:
https://doaj.org/article/e5757031ca2a4785950adcdc9ace71f2