Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gurmannat Kalra"'
Autor:
Gurmannat Kalra, Danielle Lenz, Dunia Abdul-Aziz, Craig Hanna, Mahashweta Basu, Brian R. Herb, Carlo Colantuoni, Beatrice Milon, Madhurima Saxena, Amol C. Shetty, Ronna Hertzano, Ramesh A. Shivdasani, Seth A. Ament, Albert S.B. Edge
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113421- (2023)
Summary: We explore the changes in chromatin accessibility and transcriptional programs for cochlear hair cell differentiation from postmitotic supporting cells using organoids from postnatal cochlea. The organoids contain cells with transcriptional
Externí odkaz:
https://doaj.org/article/41e88d4f61974a9aa88109f9cfc014da
Autor:
Gurmannat Kalra, Beatrice Milon, Alex M Casella, Brian R Herb, Elizabeth Humphries, Yang Song, Kevin P Rose, Ronna Hertzano, Seth A Ament
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009025 (2020)
Age-related hearing impairment (ARHI), one of the most common medical conditions, is strongly heritable, yet its genetic causes remain largely unknown. We conducted a meta-analysis of GWAS summary statistics from multiple hearing-related traits in th
Externí odkaz:
https://doaj.org/article/4350f231662f4972a40dd8d76fb52664
Autor:
Nasrine Bendjilali, Samuel MacLeon, Gurmannat Kalra, Stephen D. Willis, A. K. M. Nawshad Hossian, Erica Avery, Olivia Wojtowicz, Mark J. Hickman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 1, Pp 221-231 (2017)
Many cells experience hypoxia, or low oxygen, and respond by dramatically altering gene expression. In the yeast Saccharomyces cerevisiae, genes that respond are required for many oxygen-dependent cellular processes, such as respiration, biosynthesis
Externí odkaz:
https://doaj.org/article/235ab15fc679477ea149cb1387f0126e
Autor:
Craig Hanna, Beatrice Milon, Amol C. Shetty, Carlo Colantuoni, Ramesh A. Shivdasani, Dunia Abdul-Aziz, Gurmannat Kalra, Danielle R. Lenz, Seth A. Ament, Ronna Hertzano, Brian R. Herb, Albert S.B. Edge, Madhurima Saxena
We explored the transcriptional and epigenetic programs underlying the differentiation of hair cells from postnatal progenitor cells in cochlear organoids. Heterogeneity in the cells including cells with the transcriptional signatures of mature hair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad8953b932da8e596743b8cd1db1ca60
https://doi.org/10.1101/2021.09.19.460948
https://doi.org/10.1101/2021.09.19.460948
Autor:
Babitha Machireddy, Subash C. Jonnalagadda, Chun Wu, Kandalam V. Ramanujachary, Gurmannat Kalra
Publikováno v:
Journal of Chemical Information and Modeling. 57:2846-2864
Human telomeric DNA G-quadruplex has been identified as a good therapeutic target in cancer treatment. G-quadruplex-specific ligands that stabilize the G-quadruplex have great potential to be developed as anticancer agents. Two crystal structures (an
Autor:
Samuel MacLeon, Gurmannat Kalra, A K M Nawshad Hossian, Nasrine Bendjilali, Erica Avery, Stephen D. Willis, Mark J. Hickman, Olivia Wojtowicz
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 1, Pp 221-231 (2017)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Many cells experience hypoxia, or low oxygen, and respond by dramatically altering gene expression. In the yeast Saccharomyces cerevisiae, genes that respond are required for many oxygen-dependent cellular processes, such as respiration, biosynthesis
Autor:
Beatrice Milon, Ronna Hertzano, Seth A. Ament, Brian R. Herb, Gurmannat Kalra, Kevin Rose, Alex M. Casella, Yang Song
Age-related hearing impairment (ARHI), one of the most common medical conditions, is strongly heritable, yet its genetic causes remain largely unknown. We conducted a meta-analysis of GWAS summary statistics from multiple hearing-related traits in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c930353e3a45b499f0521dca42b97b0
https://doi.org/10.1101/562405
https://doi.org/10.1101/562405
Autor:
Soren Snitker, Joshua P. Lewis, Nanette I. Steinle, Gurmannat Kalra, Michael Miller, Simeon I. Taylor, Man Zhang, Huichun Xu, Alan R. Shuldiner, Kathleen A. Ryan, Braxton D. Mitchell, Carole Sztalryd
BACKGROUND: Post-prandial lipemia (PPL), defined as a prolonged or elevated rise in triglycerides that accompanies fat feeding, is a significant risk factor for coronary heart disease (CHD) and associated comorbidities. The impact of PPL on CHD risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4214cfa0d55c37e97d0cc9c67f424fa0
https://europepmc.org/articles/PMC6379118/
https://europepmc.org/articles/PMC6379118/
Autor:
Yang Song, Seth A. Ament, Elizabeth Humphries, Kevin Rose, Beatrice Milon, Brian R. Herb, Gurmannat Kalra, Alex M. Casella, Ronna Hertzano
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 9, p e1009025 (2020)
PLoS Genetics, Vol 16, Iss 9, p e1009025 (2020)
Age-related hearing impairment (ARHI), one of the most common medical conditions, is strongly heritable, yet its genetic causes remain largely unknown. We conducted a meta-analysis of GWAS summary statistics from multiple hearing-related traits in th