Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gurman S. Pall"'
Autor:
Manuela S Pieperhoff, Gurman S Pall, Elena Jiménez-Ruiz, Sujaan Das, Carmen Melatti, Matthew Gow, Eleanor H Wong, Joanne Heng, Sylke Müller, Michael J Blackman, Markus Meissner
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130356 (2015)
The functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencing. U
Externí odkaz:
https://doaj.org/article/acaad93cffd543fbb349e6c90b019fb4
Autor:
Isabelle Tardieux, Gurman S. Pall, Jake Baum, Markus Meissner, Oliver Lyth, Javier Periz, Mario Del Rosario, Fernanda Latorre-Barragan, Georgios Pavlou, Jamie Whitelaw, Leandro Lemgruber, Johannes Felix Stortz, Sujaan Das
Publikováno v:
EMBO Reports
The obligate intracellular parasites Toxoplasma gondii and Plasmodium spp. invade host cells by injecting a protein complex into the membrane of the targeted cell that bridges the two cells through the assembly of a ring‐like junction. This circula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf27c95a3e172631da35234c7348dab0
https://doi.org/10.15252/embr.201948896
https://doi.org/10.15252/embr.201948896
Autor:
Mario Del Rosario, Javier Periz, Georgios Pavlou, Oliver Lyth, Fernanda Latorre-Barragan, Sujaan Das, Gurman S. Pall, Johannes Felix Stortz, Leandro Lemgruber, Jake Baum, Isabelle Tardieux, Markus Meissner
The obligate intracellular parasites Toxoplasma gondii and Plasmodium spp. invade host cells by injecting a protein complex into the membrane of the targeted cell that bridges the two cells through the assembly of a ring-like junction. This circular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fa82f3e8fbce0977a18306da7346ea
https://doi.org/10.1101/646463
https://doi.org/10.1101/646463
Autor:
Juliette Morlon-Guyot, Markus Meissner, Gurman S. Pall, Isabelle Sauquet, Wassim Daher, Laurence Berry, Hiba El Hajj
Publikováno v:
Molecular and biochemical parasitology. 223
Toxoplasma gondii which is a member of the coccidian parasites owns a spatially polarized secretory system, which synthesizes de novo micronemes and rhoptries. These apical secretory organelles discharge their contents into host cells promoting invas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284e5e7aeed11ccaeecf644fe3e6f81f
https://pubmed.ncbi.nlm.nih.gov/29958928
https://pubmed.ncbi.nlm.nih.gov/29958928
Publikováno v:
Parasitology. 141:1390-1398
SUMMARYThe dissection of apicomplexan biology has been highly influenced by the genetic tools available for manipulation of parasite DNA. Here, we describe different techniques available for the generation of conditional mutants. Comparison of the ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b527bfaba870e819437513fd56e3a57c
https://doi.org/10.1017/s0031182014000559
https://doi.org/10.1017/s0031182014000559
Autor:
Jamie A, Whitelaw, Fernanda, Latorre-Barragan, Simon, Gras, Gurman S, Pall, Jacqueline M, Leung, Aoife, Heaslip, Saskia, Egarter, Nicole, Andenmatten, Shane R, Nelson, David M, Warshaw, Gary E, Ward, Markus, Meissner
Publikováno v:
BMC Biology
Background Apicomplexan parasites employ a unique form of movement, termed gliding motility, in order to invade the host cell. This movement depends on the parasite’s actomyosin system, which is thought to generate the force during gliding. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::531d2c6cf8e7f6095882b2cd6e4621d3
https://pubmed.ncbi.nlm.nih.gov/28100223
https://pubmed.ncbi.nlm.nih.gov/28100223
Autor:
Mariana, Serpeloni, Elena, Jiménez-Ruiz, Newton Medeiros, Vidal, Constanze, Kroeber, Nicole, Andenmatten, Leandro, Lemgruber, Patricia, Mörking, Gurman S, Pall, Markus, Meissner, Andréa R, Ávila
Publikováno v:
Molecular Microbiology
Summary Nucleo‐cytoplasmic RNA export is an essential post‐transcriptional step to control gene expression in eukaryotic cells and is poorly understood in apicomplexan parasites. With the exception of UAP56, a component of TREX (Transcription Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::126aeeab815b27e260e96774dba96c30
https://pubmed.ncbi.nlm.nih.gov/27542978
https://pubmed.ncbi.nlm.nih.gov/27542978
Autor:
Y. Chan N. Pham, Glenn E. Morris, Caroline Sewry, Gurman S. Pall, Ian Holt, Nguyen thi Man, Keith J. Johnson
Publikováno v:
Journal of Cellular Biochemistry. 95:990-1001
SIX5 is a member of the human SIX family of transcription factors, many of which are involved in eye development. However, SIX5 transcripts are known to be present at very low levels in cells and no study has yet convincingly demonstrated detection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33ca31f57e03307172861f14a407b16
https://doi.org/10.1002/jcb.20454
https://doi.org/10.1002/jcb.20454
Publikováno v:
Physiological Genomics. 13:139-146
Dysfunction of the gene encoding DMPK (myotonic dystrophy protein kinase) has been implicated in the human neuromuscular disease myotonic dystrophy (DM1). The cardiac features of the disease include progressive conduction defects and ventricular arrh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c170fc38be231b5a245c013337f46e
https://doi.org/10.1152/physiolgenomics.00107.2002
https://doi.org/10.1152/physiolgenomics.00107.2002
Autor:
Gurman S. Pall, Eleanor H. Wong, Manuela S. Pieperhoff, Michael J. Blackman, Sujaan Das, Elena Jiménez-Ruiz, Sylke Mueller, Joanne Heng, Markus Meissner
In absence of powerful siRNA approaches, the functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4108885755f523438b27f21590a8da9
https://doi.org/10.1101/008649
https://doi.org/10.1101/008649