Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gurkishan Chadha"'
Autor:
Melanie A. Felmlee, Gurkishan Chadha, Marilyn E. Morris, Bridget L. Morse, Kristin E. Follman
Publikováno v:
The American Journal of Drug and Alcohol Abuse. 43:686-693
Background: γ-hydroxybutyrate (GHB) has a high potential for illicit use; overdose of this compound results in sedation, respiratory depression and death. Tolerance to the hypnotic/sedative and ele...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7decb8d51e1b6cd3c32220fc19df5673
https://doi.org/10.1080/00952990.2017.1339055
https://doi.org/10.1080/00952990.2017.1339055
Autor:
Marilyn E. Morris, Gurkishan Chadha
Publikováno v:
Current Pharmacology Reports. 2:45-56
The incidence of diabetes mellitus (DM) is increasing worldwide, and both type 1 as well as type 2 DM patients are at high risk of developing diabetic nephropathy (DN). Although the effects of DM and DN have been well documented for low molecular wei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1161c74b3ead7733ceb1888b5a5dd4e6
https://doi.org/10.1007/s40495-016-0048-z
https://doi.org/10.1007/s40495-016-0048-z
Autor:
Marilyn E. Morris, Gurkishan Chadha
Publikováno v:
The AAPS Journal. 17:965-975
The objective of this research was to assess the effects of type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN) on the pharmacokinetics of human IgG (hIgG), an antibody isotype, in Zucker diabetic fatty (ZDF) rats. Furthermore, the specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0729d758057958c8402804370f97a825
https://doi.org/10.1208/s12248-015-9771-3
https://doi.org/10.1208/s12248-015-9771-3
Autor:
Marilyn E. Morris, Gurkishan Chadha
Publikováno v:
The AAPS journal. 17(6)
Although many studies have evaluated the effects of type 2 diabetes mellitus (T2DM) on the pharmacokinetics (PK) of low molecular weight molecules, there is limited information regarding effects on monoclonal antibodies. Our previous studies have rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84473cfd71a0b5ad00e8cf27b8bb8166
https://pubmed.ncbi.nlm.nih.gov/26276217
https://pubmed.ncbi.nlm.nih.gov/26276217
Publikováno v:
Drug development and industrial pharmacy. 37(5)
The objective of this study was to formulate genistein as a topical gel with various penetration enhancers for increased permeation and retention in human skin. The high performance liquid chromatography assay method was validated for precision and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6b02f7458770ff9f3ad4c58580cece
https://pubmed.ncbi.nlm.nih.gov/21126208
https://pubmed.ncbi.nlm.nih.gov/21126208
Publikováno v:
Journal of drug targeting. 18(9)
Transdermal iontophoretic delivery of selegiline hydrochloride (SH) across dermatomed human skin was studied. Electrochemical stability and various factors affecting the skin permeation were investigated. SH was stable under the influence of an elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8b2bd329c7805b2bcfcbac407af6d2
https://pubmed.ncbi.nlm.nih.gov/20038213
https://pubmed.ncbi.nlm.nih.gov/20038213
Autor:
William R. Ravis, Gurkishan Chadha, R. Jayachandra Babu, Vijay K. Rangari, Daniel L. Parsons, Y.-H. Phillip Lee, Nydeia Wright, Y.-J. Jean Lin, Sateesh Sathigari
Publikováno v:
Drug development and industrial pharmacy. 35(9)
Gefitinib, an anticancer drug, has an extremely low aqueous solubility, and its oral absorption is limited by its dissolution rate. The solubility and dissolution of gefitinib can be improved by complexation with cyclodextrins (CDs).Phase solubility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f565c232b666da68afd91ab78fc0fa8f
https://pubmed.ncbi.nlm.nih.gov/19640249
https://pubmed.ncbi.nlm.nih.gov/19640249
Autor:
Y-H. Phillip Lee, Daniel L. Parsons, Sateeshkumar Sathigari, Vijay K. Rangari, Gurkishan Chadha, Nydeia Wright, Oladiran Fasina, R. Jayachandra Babu
Efavirenz (EFV) is an oral antihuman immunodeficiency virus type 1 drug with extremely poor aqueous solubility. Thus, its gastrointestinal absorption is limited by the dissolution rate of the drug. The objective of this study was to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3777838004a5c0a990897a9592e25945
https://europepmc.org/articles/PMC2663670/
https://europepmc.org/articles/PMC2663670/
