Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gurjinder M. K. Nijher"'
Autor:
Mohammad A. Ghatei, Nicola Bridges, Shakunthala Narayanaswamy, Waljit S. Dhillo, Channa N. Jayasena, Akila De Silva, Stephen R. Bloom, Gurjinder M. K. Nijher, Ali Abbara
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 51:89-96
Background Kisspeptin is a hypothalamic neuropeptide playing a physiological role in human reproduction. Genetic over-activation of kisspeptin causes precocious puberty in children. Concentrations of circulating kisspeptin are low in adults. The conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ebc290273afecb692fd51c6e58013f
https://doi.org/10.1177/0004563213485230
https://doi.org/10.1177/0004563213485230
Autor:
Deborah Ashby, Rehan Salim, Stuart Lavery, Risheka Ratnasabapathy, Gurjinder M. K. Nijher, Deborah Peters, Ali Abbara, Shakunthala Narayanaswamy, Waljit S. Dhillo, Julia K Prague, Matyas Szigeti, Alexander N Comninos, Adam Buckley, Channa N. Jayasena, Stephen R. Bloom, Georgios Christopoulos, Geoffrey Trew, Chioma Izzi-Engbeaya
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context: In vitro fertilization (IVF) treatment is an effective therapy for infertility, but can result in the potentially life-threatening complication, ovarian hyperstimulation syndrome (OHSS). Objective: This study aimed to investigate whether kis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a8e89f1c3d8ccae8cd64ba537bb985
https://pubmed.ncbi.nlm.nih.gov/26192876
https://pubmed.ncbi.nlm.nih.gov/26192876
Autor:
Chioma Izzi-Engbeaya, Shakunthala Narayanaswamy, Manish Modi, Holly Clarke, Waljit S. Dhillo, Channa N. Jayasena, Karim Meeran, Gurjinder M. K. Nijher
SummaryBackground Cardiovascular complications represent the biggest cause of mortality in acromegaly. It is therefore important to optimally stratify acromegalic patients according to disease activity and complication risk. GH is secreted in a pulsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2c5e289dae0c4374248f5ab45b947d
http://hdl.handle.net/10044/1/25360
http://hdl.handle.net/10044/1/25360
Autor:
Shivani Misra, Gurjinder M. K. Nijher, Niamh M. Martin, Miraj Patel, Elaine Murphy, Karim Meeran
Publikováno v:
Clinical endocrinology. 77(4)
SummaryContext Lithium increases iodine retention in the thyroid gland and inhibits thyroid hormone release. Although lithium has been reported to improve the efficacy of radioactive iodine (RAI) treatment in Graves' disease, its role as an adjunct t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31e58dc2c699e67a609785af25c75ce
https://pubmed.ncbi.nlm.nih.gov/22443227
https://pubmed.ncbi.nlm.nih.gov/22443227
Autor:
Gurjinder M. K. Nijher, Ali Abbara, Stephen R. Bloom, Adam Januszewki, Labosshy Sriskandarajah, Mohammad A. Ghatei, Waljit S. Dhillo, Zohreh Farzad, Alexander N Comninos, Kevin Murphy, Meriel Vaal, Channa N. Jayasena
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism; Vol 96
Background: Kisspeptin peptides are critical in human reproductive physiology and are potential therapies for infertility. Kisspeptin-10 stimulates gonadotropin release in both male and female rodents. However, few studies have investigated the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abdf934e3077d2ca438b86abf10f442
https://pubmed.ncbi.nlm.nih.gov/21976724
https://pubmed.ncbi.nlm.nih.gov/21976724
Autor:
Gurjinder M K, Nijher, Owais B, Chaudhri, Radha, Ramachandran, Kevin G, Murphy, Sagen E K, Zac-Varghese, Alexis, Fowler, Krishna, Chinthapalli, Michael, Patterson, Emily L, Thompson, Catherine, Williamson, Sailesh, Kumar, Mohammad A, Ghatei, Stephen R, Bloom, Waljit S, Dhillo
Publikováno v:
British journal of clinical pharmacology. 70(5)
To investigate (i) if kisspeptin administration alters heart rate (HR) or blood pressure (BP) in healthy male and female volunteers, (ii) whether circulating plasma kisspeptin concentrations in healthy pregnant women and women with hypertensive disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::183847cdb0f4012245adcd47e3e9e5be
https://pubmed.ncbi.nlm.nih.gov/21039761
https://pubmed.ncbi.nlm.nih.gov/21039761
Autor:
Gurjinder M. K. Nijher, Catherine Williamson, Alexis Fowler, Owais B. Chaudhri, Jordan E. Baxter, Krishna Chinthapalli, Kevin Murphy, Waljit S. Dhillo, Sailesh Kumar, Channa N. Jayasena, Radha Ramachandran, Mohammad A. Ghatei, Stephen R. Bloom, Michael Patterson
Publikováno v:
Clinical chemistry. 56(6)
Kisspeptin is the product of the KISS1 1 (KiSS-1 metastasis-suppressor) gene and is the ligand for the G-protein–coupled receptor, now known as the KISS1 receptor (KISS1R)2 (1). Both kisspeptin and KISS1R play a crucial role in the regulation of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badd012a997206875319db87318ee5c3
https://pubmed.ncbi.nlm.nih.gov/20348399
https://pubmed.ncbi.nlm.nih.gov/20348399
Publikováno v:
Drug newsperspectives. 22(10)
Kisspeptin appears to have a pivotal role in the regulation of reproductive function and may have a therapeutic role in the treatment of disorders of reproduction. In this review we summarise the evidence regarding kisspeptin and its function in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfc080b9d4f7b59096df7fe1b9b0ab8
https://pubmed.ncbi.nlm.nih.gov/20140277
https://pubmed.ncbi.nlm.nih.gov/20140277
Autor:
Channa N, Jayasena, Gurjinder M K, Nijher, Owais B, Chaudhri, Kevin G, Murphy, Amita, Ranger, Adrian, Lim, Daksha, Patel, Amrish, Mehta, Catriona, Todd, Radha, Ramachandran, Victoria, Salem, Gordon W, Stamp, Mandy, Donaldson, Mohammad A, Ghatei, Stephen R, Bloom, Waljit S, Dhillo
Publikováno v:
The Journal of clinical endocrinology and metabolism. 94(11)
Kisspeptin is a critical regulator of normal reproductive function. A single injection of kisspeptin in healthy human volunteers potently stimulates gonadotropin release. However, the effects of kisspeptin on gonadotropin release in women with hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b06d257818ccc2e3db38ab7364f9b06
https://pubmed.ncbi.nlm.nih.gov/19820030
https://pubmed.ncbi.nlm.nih.gov/19820030
Autor:
Johannes D. Veldhuis, Adrian Lim, S.R. Bloom, Channa N. Jayasena, Gurjinder M. K. Nijher, Ali Abbara, Akila De Silva, Risheka Ratnasabapathy, Chioma Izzi-Engbeaya, Alexander N Comninos, Waljit S. Dhillo, Mohammad A. Ghatei, Daksha Patel
Publikováno v:
The Lancet. 383:S37
Background Kisspeptin (encoded by the KISS1 gene) is a crucial regulator of normal reproductive function. In human beings, KISS1 deletion results in a failure to go through puberty whereas activating mutations result in central precocious puberty. Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2dd198ebde914f447fc34478ff06b8f
https://doi.org/10.1016/s0140-6736(14)60300-7
https://doi.org/10.1016/s0140-6736(14)60300-7