Proinflammatory cytokines induce rapid, NO-independent apoptosis, expression of chemotactic mediators and interleukin-32 secretion in human pluripotent stem cell-derived beta cells.

Autor: Dettmer R; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Niwolik I; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Cirksena K; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Yoshimoto T; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany.; Department of Digestive and Transplant Surgery, Tokushima University, Tokushima, Japan., Tang Y; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Mehmeti I; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Gurgul-Convey E; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Naujok O; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany. naujok.ortwin@mh-hannover.de.

Publikováno v: Diabetologia [Diabetologia] 2022 May; Vol. 65 (5), pp. 829-843. Date of Electronic Publication: 2022 Feb 05.

To Be or Not to Be: The Divergent Action and Metabolism of Sphingosine-1 Phosphate in Pancreatic Beta-Cells in Response to Cytokines and Fatty Acids.

Autor: Gurgul-Convey E; Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 31; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 31.

MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity.

Autor: Tyka K; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Jörns A; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Dunst A; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Tang Y; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Bryde TH; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mehmeti I; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Walentinsson A; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Marselli L; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Cnop M; ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles (ULB), Brussels, Belgium., Tyrberg B; Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Institute de Recherche Servier, Suresenes, France., Marzec MT; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gurgul-Convey E; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany. Electronic address: Gurgul-Convey.Ewa@mh-hannover.de.

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2021 Oct 01; Vol. 1867 (10), pp. 166199. Date of Electronic Publication: 2021 Jun 16.

The Role of 11-Oxygenated Androgens and Endocrine Disruptors in Androgen Excess Disorders in Women.

Autor: Vitku, Jana¹ (AUTHOR) avarausova@endo.cz, Varausova, Anezka¹ (AUTHOR) tskodova@endo.cz, Skodova, Tereza¹ (AUTHOR) lkolatorova@endo.cz, Kolatorova, Lucie¹ (AUTHOR) msimkova@endo.cz, Vosatkova, Michala² (AUTHOR) mvosatkova@endo.cz, Vcelak, Josef³ (AUTHOR) jvcelak@endo.cz, Vrbikova, Jana⁴ (AUTHOR) jvrbikova@endo.cz, Simkova, Marketa¹ (AUTHOR) msvojtkova@endo.cz, Svojtkova, Michaela¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9691. 18p.

Immunometabolism in type 2 diabetes mellitus: tissue-specific interactions.

Autor: Pinheiro-Machado E; Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands., Gurgul-Convey E; Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany., Marzec MT; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: Archives of medical science : AMS [Arch Med Sci] 2020 Jan 31; Vol. 19 (4), pp. 895-911. Date of Electronic Publication: 2020 Jan 31 (Print Publication: 2023).