Synthesis of 1-[ω-(Bromophenoxy)alkyl]-3-naphthalenylmethyl Derivatives of Uracil and Their Analogues As Probable Inhibitors of Human Cytomegalovirus Replication.

Autor: Paramonova MP; Volgograd State Medical University, Volgograd, Russia., Gureeva ES; Volgograd State Medical University, Volgograd, Russia., Ozerov AA; Volgograd State Medical University, Volgograd, Russia., Snoeck R; Rega Institute for Medical Research, KU Leuven, Leuven B-3000, Belgium., Andrei G; Rega Institute for Medical Research, KU Leuven, Leuven B-3000, Belgium., Aleksandrov DA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Khandazhinskaya AL; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. khandazhinskaya@bk.ru., Novikov MS; Volgograd State Medical University, Volgograd, Russia., Kochetkov SN; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. snk1952@gmail.com.

Publikováno v: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2023 Apr; Vol. 509 (1), pp. 41-46. Date of Electronic Publication: 2023 Jun 20.

Antiviral Activity of N 1 ,N 3 -Disubstituted Uracil Derivatives against SARS-CoV-2 Variants of Concern.

Autor: Siniavin AE; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.; Department of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Novikov MS; Department of Pharmaceutical & Toxicological Chemistry, Volgograd State Medical University, 400131 Volgograd, Russia., Gushchin VA; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.; Department of Virology, Lomonosov Moscow State University, 119991 Moscow, Russia., Terechov AA; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Ivanov IA; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.; Department of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Paramonova MP; Department of Pharmaceutical & Toxicological Chemistry, Volgograd State Medical University, 400131 Volgograd, Russia., Gureeva ES; Department of Pharmaceutical & Toxicological Chemistry, Volgograd State Medical University, 400131 Volgograd, Russia., Russu LI; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Kuznetsova NA; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Shidlovskaya EV; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Luyksaar SI; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Vasina DV; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Zolotov SA; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Zigangirova NA; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Logunov DY; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia., Gintsburg AL; N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.; Department of Infectiology and Virology, Federal State Autonomous Educational Institution of Higher Education I M Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119435 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 05; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 05.