Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gurdal Sahin"'
Autor:
Fabia Febbraro, Gurdal Sahin, Aina Farran, Sofia Soares, Poul H. Jensen, Deniz Kirik, Marina Romero-Ramos
Publikováno v:
Neurobiology of Disease, Vol 56, Iss , Pp 47-58 (2013)
Alpha-synuclein phosphorylated at serine 129 (S129) is highly elevated in Parkinson's disease patients where it mainly accumulates in the Lewy bodies. Several groups have studied the role of phosphorylation at the S129 in α-synuclein in a rat model
Externí odkaz:
https://doaj.org/article/d0fadbd0a5e146d188a2e3262299e943
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 2, Pp 222-227 (2012)
l-DOPA is currently the standard treatment for alleviating the motor symptoms in Parkinson's disease. The therapeutic efficacy, however, diminishes as the disease progresses. It has been suggested that the beneficial effect of l-DOPA could be reestab
Externí odkaz:
https://doaj.org/article/f2da9c83c4bd41ee888e414903b990c8
Autor:
Gurdal Sahin, Lachlan H Thompson, Sonia Lavisse, Merve Ozgur, Latifa Rbah-Vidal, Frédéric Dollé, Philippe Hantraye, Deniz Kirik
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90759 (2014)
Dyskinesia is a major side effect of an otherwise effective L-DOPA treatment in Parkinson's patients. The prevailing view for the underlying presynaptic mechanism of L-DOPA-induced dyskinesia (LID) suggests that surges in dopamine (DA) via uncontroll
Externí odkaz:
https://doaj.org/article/7a39cbc361044a258d20cb9a92cbb3b7
Autor:
Fabia Febbraro, Gurdal Sahin, Aina Farran, Sofia Soares, Poul H. Jensen, Deniz Kirik, Marina Romero-Ramos
Publikováno v:
Neurobiology of Disease, Vol 58, Iss , Pp 191- (2013)
Externí odkaz:
https://doaj.org/article/d3f3021cc9f5496ca743618795a895d2
Autor:
Messoud Ashina, Dimos D. Mitsikostas, Faisal M. Amin, Pinar Kokturk, Gurdal Sahin, Christoph J. Schankin, Paul J. Dorman, Patricia Pozo-Rosich, Leonidas Lyras, Coleen Myers, Andrew H. Ahn, Cristina Tassorelli
Publikováno v:
Wednesday, April 26.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89cbb228ac4e0d0f4830389d7578662e
https://doi.org/10.1212/wnl.0000000000202844
https://doi.org/10.1212/wnl.0000000000202844
Publikováno v:
Cephalalgia Reports, Vol 7 (2024)
Background There is a growing awareness of constipation being a side effect of anti-calcitonin gene-related peptide (anti-CGRP) monoclonal antibodies (mAbs). This study aims to assess constipation as a side effect and explore its potential role as a
Externí odkaz:
https://doaj.org/article/616079f3cc784d17a17d5b15e375c274
Publikováno v:
Balkan Medical Journal, Vol 39, Iss 5, Pp 318-333 (2022)
Parkinson’s disease (PD) is a complex, chronic, and progressive neurodegenerative disease that is characterized by irreversible dopaminergic neuronal loss in the substantia nigra. Alpha-synuclein is normally a synaptic protein that plays a key role
Externí odkaz:
https://doaj.org/article/18f80a5089374386bdc756602273acec
Publikováno v:
Molecular Therapy; Vol 20
Molecular Therapy; 20(7), pp 1315-1326 (2012)
Molecular Therapy
Molecular Therapy; 20(7), pp 1315-1326 (2012)
Molecular Therapy
Preclinical efficacy of continuous delivery of 3,4-dihydroxyphenylalanine (DOPA) with adeno-associated viral (AAV) vectors has recently been documented in animal models of Parkinson's disease (PD). So far, all studies have utilized a mix of two monoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bbb044acaab64287162a5667dcbf81
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
The presence of focal EEG abnormalities in juvenile absence syndrome (JAS) may cause it to be misdiagnosed as focal epilepsy. The purpose of our study was to determine the presence of focal EEG abnormalities in patients with JAS and to ascertain whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad39c7a3a1420c26a7b1c2937fe6aa0
https://doi.org/10.1177/155005940803900111
https://doi.org/10.1177/155005940803900111
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveTo report the efficacy of different anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) on headache frequency, intensity, and duration.BackgroundBlockade of CGRP receptors or neuropeptide with anti-CGRP mAbs have been su
Externí odkaz:
https://doaj.org/article/036c0c66296143a289d037996e512658