Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gurbet, Korkmaz"'
Autor:
Ozcan Karaman, Nazli Ezgi Ozkan, Gurbet Korkmaz, Seda Turgut, Muzaffer Ilhan, Ertuğrul Tasan, Saime Turan, Ilhan Yaylim
Objevtive: Acromegaly is a rare disease characterized by growth hormone hypersecretion generally arising from pituitary adenomas. Survivin, an apoptosis inhibitor protein, plays an important role in cell cycle regulation and possibly involves hypophy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b021fd999a32a56142a9ce35e1b32954
http://hdl.handle.net/20.500.12645/28681
http://hdl.handle.net/20.500.12645/28681
Autor:
Cem Horozoglu, Uteuliyev Yerzhan Sabitaliyevich, Ozlem Timirci Kahraman, Ammad Ahmad Farooqi, Nazlı Ezgi Ozkan Kucuk, Soykan Arikan, Gurbet Korkmaz, Saime Turan, Ilhan Yaylim, Esra Canan Kelten Talu
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 65(8)
Rapidly accumulating preclinical and clinical studies have helped us to unveil underlying mechanisms of colorectal cancer development and progression. Deregulated signaling pathways play instrumental role in carcinogenesis, drug resistance and metast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e291f499096d178f1c9cb64947ee19fc
https://pubmed.ncbi.nlm.nih.gov/32133972
https://pubmed.ncbi.nlm.nih.gov/32133972
Akademický článek
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Autor:
Levent Verim, Nazli Ezgi Ozkan, Canan Cacina, Bahar Toptaş, Saime Turan, Gurbet Korkmaz, Ilhan Yaylim
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 14:665-668
Endothelial nitric oxide synthase (eNOS), encoded by the NOS3 gene, has been suggested to play an important role in uncontrolled cell growth in several cancer types. The objective of this study was to evaluate the role of the NOS3 Glu298Asp polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120b771af4b17022274e1b615a5d88aa
https://doi.org/10.7314/apjcp.2013.14.2.665
https://doi.org/10.7314/apjcp.2013.14.2.665
Autor:
Elif I, Ikitimur-Armutak, Engin, Ulukaya, Ebru, Gurel-Gurevin, Ilhan, Yaylim, Banu, Isbilen-Basok, Gulbin, Sennazli, Gulay, Yuzbasioglu-Ozturk, Kivilcim, Sonmez, Faruk, Celik, Ozlem, Kucukhuseyin, Gurbet, Korkmaz, Veysel T, Yilmaz, Sakir Umit, Zeybek
Publikováno v:
In vivo (Athens, Greece). 30(4)
New compounds for cancer treatment are needed due to persistenly unsatisfactory management of cancer. [PdCl(terpy)](sac)·2H2O] (sac=saccharinate, and terpy=2,2':6',2"-terpyridine) is a compound synthesized for this purpose. We investigated its anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::518172e2745e9fac9ab365047a84e771
https://pubmed.ncbi.nlm.nih.gov/27381609
https://pubmed.ncbi.nlm.nih.gov/27381609
Autor:
Ozlem Kucukhuseyin, Tamer Cebe, Gurbet Korkmaz, Karolin Yanar, Nazli Ezgi Ozkan, Seval Aydin, Pinar Atukeren, Kadircan Karatoprak, Ayşegül Verim, Canan Cacina, Saime Turan, Elif Ozkok, Ufuk Çakatay, Ilhan Yaylim
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Nitric oxide synthase (eNOS/NOS3) is responsible for the endothelial synthesis of nitric oxide (NO•). G894T polymorphism leads to the amino acid substitution from Glu298Asp that causes lower NOS3 activity and basal NO•production in NOS3 894T (298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b971e0bea98351dc23b163d187c5782
https://doaj.org/article/58d76bc22b294d2a8a7287527f712170
https://doaj.org/article/58d76bc22b294d2a8a7287527f712170
Autor:
Saime Turan, Soykan Arikan, Esra Sağlam, Ozlem Timirci Kahraman, Nazli Ezgi Ozkan, Ezgi Nurdan Yenilmez, Cem Horozoglu, Arzu Ergen, Mehmet Dogan, Zeynep Güral, Umit Zeybek, Ilhan Yaylim, Yigit Duzkoylu, Gurbet Korkmaz
Publikováno v:
Bosnian Journal of Basic Medical Sciences
Bosnian Journal of Basic Medical Sciences, Vol 16, Iss 2 (2016)
Bosnian Journal of Basic Medical Sciences, Vol 16, Iss 2 (2016)
The Wnt pathway alterations have been identified in colorectal and many other cancer types. It has been reported that galectin-3 (which is encoded by the LGALS3 gene) alters the signaling mechanism in the Wnt/ β-catenin pathway by binding to β-cate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a556b479610a348ffbd08c5e7f48498
https://doi.org/10.17305/bjbms.2016.721
https://doi.org/10.17305/bjbms.2016.721
Autor:
Nazli Ezgi Ozkan, Bahar Toptaş, Ilhan Yaylim, Yemliha Yildiz, Saime Turan, Soykan Arikan, Gurbet Korkmaz, Canan Cacina
Publikováno v:
Journal of Cancer Therapy. :941-947
Programmed cell death called apoptosis, plays an important role in the development and maintenance of tissue homeostasis and abnormalities in apoptotic function have been known as important events in the pathogenesis of many cancer types, such as col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e027c11d8b1f4dd62f330067d5085e86
https://doi.org/10.4236/jct.2012.326120
https://doi.org/10.4236/jct.2012.326120
Autor:
Saime Turan, Canan Cacina, Ilhan Yaylim, Nazli Ezgi Ozkan, Turgay Isbir, Aysegul Verim, Gurbet Korkmaz
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 14(12)
Background: Cylin D1(CCDN1) is an important regulator of the cell cycle whose alterations are thought to be involved in cancer development. There have been many studies indicating CCDN1 amplification or overexpression in a variety of cancer types. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719f2c4b238de29fee7621baef7b2c25
https://pubmed.ncbi.nlm.nih.gov/24460344
https://pubmed.ncbi.nlm.nih.gov/24460344
Autor:
Ilhan Yaylim, Nazli Ezgi Ozkan, Canan Cacina, Didem Kafadar, Umit Zeybek, Gurbet Korkmaz, Ali Metin Kafadar, Saime Turan
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 14(7)
Alterations of cyclin D1, one of the main regulators of the cell cycle, are known to be involved in various cancers. The CCDN1 G870A polymorphism causes production of a truncated variant with a shorter half-life and thus thought to impact the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98308137aca69c3cad5fbbca891aa5a6
https://pubmed.ncbi.nlm.nih.gov/23991960
https://pubmed.ncbi.nlm.nih.gov/23991960