Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Guralp O. Ceyhan"'
1
Akademický článek
Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling
Autor: Wasfi Alrawashdeh, Richard Jones, Laurent Dumartin, Tomasz P. Radon, Pedro R. Cutillas, Roger M. Feakins, Branko Dmitrovic, Ihsan Ekin Demir, Guralp O. Ceyhan, Tatjana Crnogorac‐Jurcevic
Publikováno v: Molecular Oncology, Vol 13, Iss 5, Pp 1075-1091 (2019)
Perineural invasion (PNI) is a common and characteristic feature of pancreatic ductal adenocarcinoma (PDAC) that is associated with poor prognosis, tumor recurrence, and generation of pain. However, the molecular alterations in cancer cells and nerve
Externí odkaz: https://doaj.org/article/249791bfa1a843bb877926ad1eda4076
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5
Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling
Autor: Wasfi, Alrawashdeh, Richard, Jones, Laurent, Dumartin, Tomasz P, Radon, Pedro R, Cutillas, Roger M, Feakins, Branko, Dmitrovic, Ihsan Ekin, Demir, Guralp O, Ceyhan, Tatjana, Crnogorac-Jurcevic
Publikováno v: Molecular Oncology
Perineural invasion (PNI) is a common and characteristic feature of pancreatic ductal adenocarcinoma (PDAC) that is associated with poor prognosis, tumor recurrence, and generation of pain. However, the molecular alterations in cancer cells and nerve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10ce894856ed8640594793772af4c4ed
https://pubmed.ncbi.nlm.nih.gov/30690892
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6
Akademický článek
Arterial Resection for Pancreatic Cancer: Feasibility and Current Standing in a High-Volume Center
Autor: Lei Ren, MD, Carsten Jäger, MPH, Stephan Schorn, Ilaria Pergolini, Rüdiger Göß, Okan Safak, Maximilian Kießler, Marc E. Martignoni, Alexander R. Novotny, Helmut Friess, Güralp O. Ceyhan, Ihsan Ekin Demir
Publikováno v: Annals of Surgery Open, Vol 4, Iss 3, p e302 (2023)
Background:. Arterial resection (AR) during pancreatectomy for curative R0 resection of pancreatic ductal adenocarcinoma (PDAC) remains a controversial procedure with high morbidity. Objective:. To investigate the feasibility and oncological outcomes
Externí odkaz: https://doaj.org/article/a0a7376ec8a24c4fa86e22a8b7ac848b
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7
Akademický článek
Bacterial content of the human pancreatic duct: An observational study
Autor: Elke Demir, Bengi Su Yilmaz, Carsten Jäger, Kathrin Rothe, Stephan Schorn, Ilaria Pergolini, Rüdiger Göß, Okan Safak, Dirk Wilhelm, Marc E. Martignoni, Alexander R. Novotny, Helmut Friess, Güralp O. Ceyhan, Ihsan Ekin Demir
Publikováno v: Heliyon, Vol 8, Iss 11, Pp e11771- (2022)
Background: Pancreatic fistula/PF is a challenging surgical complication. We could recently show that intestinal bacteria such as Enterobacterales colonize the PF fluid even after a “sterile” operation like distal pancreatectomy/DP. Therefore, we
Externí odkaz: https://doaj.org/article/4ddd9e8b18124d16821619121881b951
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8
Akademický článek
Innervated mouse pancreas organoids as an ex vivo model to study pancreatic neuropathy in pancreatic cancer
Autor: H. Erdinc Besikcioglu, Ümmügülsüm Yurteri, Enkhtsetseg Munkhbaatar, Linhan Ye, Fangfang Zhang, Alessandra Moretti, Carmen Mota Reyes, Candan Özoğul, Helmut Friess, Güralp O. Ceyhan, Rouzanna Istvanffy, Ihsan Ekin Demir
Publikováno v: STAR Protocols, Vol 2, Iss 4, Pp 100935- (2021)
Summary: Pancreatic cancer is characterized by bi-directional interactions between pancreatic cancer cells and stromal cells including neural cells. The absence of neural cells in pancreatic organoids limits the investigation of cell- cell interactio
Externí odkaz: https://doaj.org/article/b642699e60d54a329d6538dd1f56fe16
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9
Akademický článek
Targeting nNOS ameliorates the severe neuropathic pain due to chronic pancreatitisResearch in context
Autor: Ihsan Ekin Demir, Tobias Heinrich, Dominique G. Carty, Ömer Cemil Saricaoglu, Sarah Klauss, Steffen Teller, Timo Kehl, Carmen Mota Reyes, Elke Tieftrunk, Maria Lazarou, Dorukhan H. Bahceci, Betül Gökcek, Bahar E. Ucurum, Matthias Maak, Kalliope N. Diakopoulos, Marina Lesina, Michael Schemann, Mert Erkan, Achim Krüger, Hana Algül, Helmut Friess, Güralp O. Ceyhan
Publikováno v: EBioMedicine, Vol 46, Iss , Pp 431-443 (2019)
Background: Pain due to pancreatic cancer/PCa or chronic pancreatitis/CP, is notoriously resistant to the strongest pain medications. Here, we aimed at deciphering the specific molecular mediators of pain at surgical-stage pancreatic disease and to d
Externí odkaz: https://doaj.org/article/e5b83526ca9647e8bb16e16a99287a55
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10
Akademický článek
Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism – Update to the Human Model and Expansion of Applications
Autor: Tamara Zietek, Pieter Giesbertz, Maren Ewers, Florian Reichart, Michael Weinmüller, Elisabeth Urbauer, Dirk Haller, Ihsan Ekin Demir, Güralp O. Ceyhan, Horst Kessler, Eva Rath
Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Intestinal transport and sensing processes and their interconnection to metabolism are relevant to pathologies such as malabsorption syndromes, inflammatory diseases, obesity and type 2 diabetes. Constituting a highly selective barrier, intestinal ep
Externí odkaz: https://doaj.org/article/90bbb30042a94fc589fa4b26de6ad238
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