Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer

Autor: Hamza, Bashar, Ng, Sheng Rong, Prakadan, Sanjay M., Delgado, Francisco Feijó, Chin, Christopher R., King, Emily M., Yang, Lucy F., Davidson, Shawn M., DeGouveia, Kelsey L., Cermak, Nathan, Navia, Andrew W., Winter, Peter S., Drake, Riley S., Tammela, Tuomas, Li, Carman Man-Chung, Papagiannakopoulos, Thales, Gupta, Alejandro J., Bagnall, Josephine Shaw, Knudsen, Scott M., Vander Heiden, Matthew G., Wasserman, Steven C., Jacks, Tyler, Shalek, Alex K., Manalis, Scott R.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2019 Feb 01. 116(6), 2232-2236.

Externí odkaz: https://www.jstor.org/stable/26663808

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Mutation and cell state compatibility is required and targetable in Ph+ acute lymphoblastic leukemia minimal residual disease.

Autor: Winter PS; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Ramseier ML; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Navia AW; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Saksena S; Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.; Computational and Systems Biology Program, MIT, Cambridge, MA, USA., Strouf H; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Senhaji N; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., DenAdel A; Center for Computational Molecular Biology, Brown University, Providence, RI, USA.; Department of Biostatistics, Brown University, Providence, RI, USA., Mirza M; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., An HH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Bilal L; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Dennis P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Leahy CS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Shigemori K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Galves-Reyes J; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Zhang Y; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Department of Biological Engineering, MIT, Cambridge, MA, USA., Powers F; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Mulugeta N; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Gupta AJ; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Calistri N; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Van Scoyk A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Jones K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Liu H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Stevenson KE; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA USA., Ren S; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA USA., Luskin MR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Couturier CP; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Amini AP; Microsoft Research, Cambridge, MA, USA., Raghavan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kimmerling RJ; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Stevens MM; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Crawford L; Center for Computational Molecular Biology, Brown University, Providence, RI, USA.; Department of Biostatistics, Brown University, Providence, RI, USA.; Microsoft Research, Cambridge, MA, USA., Weinstock DM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Current Address: Merck and Co., Rahway, NJ, USA., Manalis SR; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, MIT, Cambridge, MA, USA., Shalek AK; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Murakami MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 10. Date of Electronic Publication: 2024 Jun 10.