Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Guoyu Pan"'
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109500- (2024)
Summary: Cell therapy using proliferating human hepatocytes (ProliHHs) is an effective treatment approach for advanced liver diseases. However, rapid and accurate identification of high-quality ProliHHs from different donors is challenging due to ind
Externí odkaz:
https://doaj.org/article/961045427648436db8b8048f81c644b4
Autor:
Huiying Cao, Chen Ma, Zhitao Wu, Lin Sun, Wenjing Liu, Chenhui Ma, Feihong Chen, Zhaoliang Peng, Lijiang Xuan, Ruimin Huang, Guoyu Pan
Publikováno v:
MedComm – Future Medicine, Vol 2, Iss 4, Pp n/a-n/a (2023)
Abstract The enormous incidence and dire consequences of liver fibrosis highlight the need for biologically plausible markers as readouts of pathology and drug efficacy. The classic reference standard for diagnosis of liver fibrosis is histopathologi
Externí odkaz:
https://doaj.org/article/d067c899fecf4404b725ee9174f9fa4a
Autor:
Chen Ma, Ludi Zhang, Ting He, Huiying Cao, Xiongzhao Ren, Chenhui Ma, Jiale Yang, Ruimin Huang, Guoyu Pan
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Background Cell therapy provides hope for treatment of advanced liver failure. Proliferating human hepatocytes (ProliHHs) were derived from primary human hepatocytes (PHH) and as potential alternative for cell therapy in liver diseases. Due
Externí odkaz:
https://doaj.org/article/da7787a78c2640659bf5c5c3c2acb88c
Autor:
Yaru Xue, Qiangqiang Deng, Qingli Zhang, Zhenghua Ma, Binfan Chen, Xiaolu Yu, Huige Peng, Sheng Yao, Jia Liu, Yang Ye, Guoyu Pan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Arachidonic acid (AA) signaling pathway is an important constituent of inflammatory processes. In our previous study, it was found that dihydro-stilbene gigantol relieved hepatic inflammation in mice with CCl4-induced acute liver injury. Thi
Externí odkaz:
https://doaj.org/article/5422c27e8d144a1294213cea143e9bfe
Autor:
Ludi Zhang, Jian‐Yun Ge, Yun‐Wen Zheng, Zhen Sun, Chenhua Wang, Zhaoliang Peng, Baihua Wu, Mei Fang, Kinji Furuya, Xiaolong Ma, Yanjiao Shao, Nobuhiro Ohkohchi, Tatsuya Oda, Jianglin Fan, Guoyu Pan, Dali Li, Lijian Hui
Publikováno v:
Advanced Science, Vol 8, Iss 19, Pp n/a-n/a (2021)
Abstract Although liver‐humanized animals are desirable tools for drug development and expansion of human hepatocytes in large quantities, their development is restricted to mice. In animals larger than mice, a precondition for efficient liver huma
Externí odkaz:
https://doaj.org/article/4956c6e9b5b94dd8a2f22c16eb0aefd6
Autor:
Yong Xie, Guoyu Pan, Qiang Jin, Xiaoqun Qi, Tan Wang, Wei Li, Hui Xu, Yuheng Zheng, Sa Li, Long Qie, Yunhui Huang, Ju Li
Publikováno v:
Advanced Science, Vol 7, Iss 9, Pp n/a-n/a (2020)
Abstract Lean electrolyte (small E/S ratio) is urgently needed to achieve high practical energy densities in Li–S batteries, but there is a distinction between the cathode's absorbed electrolyte (AE) which is cathode‐intrinsic and total added ele
Externí odkaz:
https://doaj.org/article/97fc73bd887e48be9842fcb626b66877
Autor:
Yimeng Gao, Xiaoran Zhang, Ludi Zhang, Jin Cen, Xuan Ni, Xiaoying Liao, Chenxi Yang, Ying Li, Xiaotao Chen, Zhao Zhang, Yajing Shu, Xin Cheng, David C. Hay, Dongmei Lai, Guoyu Pan, Gang Wei, Lijian Hui
Publikováno v:
Stem Cell Reports, Vol 9, Iss 6, Pp 1813-1824 (2017)
Summary: Hepatocyte-like cells (HLCs) can be generated through directed differentiation or transdifferentiation. Employing two strategies, we generated induced pluripotent stem cell (iPSC)-HLCs and hiHeps from the same donor cell line. Both types of
Externí odkaz:
https://doaj.org/article/307e7757042448d39eabd5eaba5c3f47
Autor:
Xin Luo, Qiangqiang Deng, Yaru Xue, Tianwei Zhang, Zhitao Wu, Huige Peng, Lijiang Xuan, Guoyu Pan
Publikováno v:
Molecules, Vol 26, Iss 6, p 1715 (2021)
Pulmonary fibrosis is a severe and irreversible interstitial pulmonary disease with high mortality and few treatments. Magnesium lithospermate B (MLB) is a hydrosoluble component of Salvia miltiorrhiza and has been reported to have antifibrotic effec
Externí odkaz:
https://doaj.org/article/90ec9eda642e47188f050a4528d24c2f
Autor:
Ning Zhang, Li Han, Yaru Xue, Qiangqiang Deng, Zhitao Wu, Huige Peng, Yiting Zhang, Lijiang Xuan, Guoyu Pan, Qiang Fu
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Acute inflammation is an important component of the pathogenesis of hepatic ischemia/reperfusion injury (HIRI). Magnesium lithospermate B (MLB) has strong neuroprotective and cardioprotective effects. The purpose of this study was to determine whethe
Externí odkaz:
https://doaj.org/article/50391370496841c6bae3f666ef32a080
Autor:
Xiaoting Tian, Fang Liu, Zhixiong Li, Yunfei Lin, Huan Liu, Pei Hu, Mingcang Chen, Zhaolin Sun, Zhou Xu, Yiting Zhang, Li Han, Yuanyuan Zhang, Guoyu Pan, Chenggang Huang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Objective: Inspired by the traditionally clinical application of herb pair Zhimu-Huangbo to treat diabetes, a combination of plant ingredients, timosaponin B2 (TB-2) and berberine (BBR), was evaluated for their anti-diabetic efficacy and cooperative
Externí odkaz:
https://doaj.org/article/87f557989a7c4b039ec9c0a8ffeeca16