Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Guoying Cao"'
Autor:
Xiaojie Wu, Nanye Chen, Peiwen Hsu, Jing Sun, Wenting Li, Qi Wang, Merali Samira, Qiong Wei, Jicheng Yu, Guoying Cao, Haijing Yang, Lili Wang, Jingjing Wang, Yi Jin, Wei Liu, Jufang Wu, Jinjie He, Cheng Lyu, Jing Zhang
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 7, Pp n/a-n/a (2024)
Abstract Obstructive hypertrophic cardiomyopathy (oHCM) is a subtype of HCM characterized by left ventricular outflow tract obstruction resulting from cardiac muscle hypertrophy and anatomic alterations in the mitral valve and apparatus. Mavacamten,
Externí odkaz:
https://doaj.org/article/2a602c72083d43b0b3bcb5b88b7e9dab
Autor:
Yuran Cao, Jingjing Wang, Xingyu Tang, Yan Tian, Jicheng Yu, Hong Liang, Jufang Wu, Yuancheng Chen, Guoying Cao, Jing Zhang
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0296940 (2024)
Mesalazine is a well-established treatment for ulcerative colitis by oral or topical administration. However, the pharmacokinetic (PK) and safety profiles of mesalazine administered by an enema has not been clarified in Chinese population. We conduct
Externí odkaz:
https://doaj.org/article/96169cf126d44edfab53b53e77677b41
Autor:
Shanshan Li, Xiaojie Wu, Nanyang Li, Guoying Cao, Jingjing Wang, Yuancheng Chen, Size Li, Jinjie He, Jufang Wu, Haijing Yang, Ke Lin, Chao Qiu, Angela Liu, He Zhou, Francisco Adrian, Liang Schweizer, Wenhong Zhang, Jingwen Gu, Jing Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objective: The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) still protracts worldwide. HFB30132A is an anti- SARS-CoV-2 monoclonal antibody purposely engineered for an extended
Externí odkaz:
https://doaj.org/article/0e5267ec43d046bda3c93c9e5f568cc1
Autor:
Guoying Cao, Jingjing Wang, Jinjie He, Yingying Hu, Haijing Yang, Linling Que, Xianghong Gu, Jicheng Yu, Xiaojie Wu, Jufang Wu, Wei Fang, Qing He, Jing Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: This study aimed to investigate the pharmacokinetics, safety, and immunogenicity of recombinant humanized anti-human IL-6R monoclonal antibody injection, LZM008, and evaluate the pharmacokinetic similarity between LZM008 and tocilizumab (
Externí odkaz:
https://doaj.org/article/35ca9972ee4242d2a23a6794d9debd44
Autor:
Yuancheng Chen, Xiaojie Wu, Chengyuan Tsai, Liwen Chang, Jicheng Yu, Guoying Cao, Beining Guo, Yaoguo Shi, Demei Zhu, Fupin Hu, Jinyi Yuan, Yang Liu, Xu Zhao, Yingyuan Zhang, Jufang Wu, Jing Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Nemonoxacin is an innovative quinolone antibiotic for treatment of community-acquired pneumonia (CAP). As more data are available from clinical studies, it is necessary to perform an integrative pharmacokinetic/pharmacodynamic (PK/PD) a
Externí odkaz:
https://doaj.org/article/102adff3a6dd4b28a447fde2e61315e0
Autor:
Yingying Hu, Qiong Wei, Xingchen Bian, Xinyi Yang, Jicheng Yu, Jingjing Wang, Haijing Yang, Guoying Cao, Xiaojie Wu, Jing Zhang
Publikováno v:
Antibiotics, Vol 12, Iss 9, p 1391 (2023)
This study aimed to explore the pharmacokinetics (PK) and safety of oral (PO) and intravenous (IV) lefamulin in healthy Chinese subjects and to evaluate the efficacy of the intravenous administration regimen using pharmacokinetic/pharmacodynamic (PK/
Externí odkaz:
https://doaj.org/article/f6960dd2cab841e2b64635aacbf695e8
Autor:
Haijing Yang, Zhiwei Huang, Yuancheng Chen, Yusong Zhu, Guoying Cao, Jingjing Wang, Yan Guo, Jicheng Yu, Jufang Wu, Lichuan Liu, Jun Deng, Jing Liu, Harald Reinhart, Jing Zhang, Xiaojie Wu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: Omadacycline is a new type of aminomethylcycline antibiotic, having a broad antibacterial spectrum. But the pharmacokinetic characteristics and safety profile of the Chinese population remain unknown. It is also unclear whether the US-appr
Externí odkaz:
https://doaj.org/article/835c36f73093449cb301f7112048faf0
Autor:
Jing Zhang, Weiguo Wan, Liyan Miao, Jian Wu, Jun Dong, Yinghua Shen, Cui Xiong, Chao Li, Yu Xue, Guoying Cao, Peiming Ma
Publikováno v:
Rheumatology and Therapy, Vol 7, Iss 1, Pp 191-200 (2020)
Abstract Introduction The B cell survival factor B lymphocyte stimulator (BLyS) is elevated in patients with systemic lupus erythematosus (SLE) and associated with disease activity. Belimumab, a monoclonal antibody specific for soluble BLyS, is appro
Externí odkaz:
https://doaj.org/article/6db7b1fd925d4dc99b88a87626b8d25e
Autor:
Yu Wang, Xiaofen Liu, Kun Li, Yaxin Fan, Jicheng Yu, Hailan Wu, Yi Li, Xiaojie Wu, Beining Guo, Xin Li, Jiali Hu, Jufang Wu, Guoying Cao, Jing Zhang
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 958 (2022)
The aim of this study was to investigate the pharmacokinetics (PK) of doripenem in healthy Chinese subjects and evaluate the optimal dosage regimens of doripenem. A randomized, single-dose, three-period, self-crossover controlled extended-infusion cl
Externí odkaz:
https://doaj.org/article/f64607f76b0d4a4d8950951ca5619fbd
Autor:
Yaxin Fan, Yi Li, Yuancheng Chen, Jicheng Yu, Xiaofen Liu, Wanzhen Li, Beining Guo, Xin Li, Jingjing Wang, Hailan Wu, Yu Wang, Jiali Hu, Yan Guo, Fupin Hu, Xiaoyong Xu, Guoying Cao, Jufang Wu, Yingyuan Zhang, Jing Zhang, Xiaojie Wu
Publikováno v:
Antibiotics, Vol 11, Iss 6, p 798 (2022)
Colistin methanesulfonate (CMS) is an important treatment option for infections caused by carbapenem-resistant Gram-negative organisms (CROs). This study evaluated the pharmacokinetic/pharmacodynamic (PK/PD) profiles and safety of CMS in Chinese subj
Externí odkaz:
https://doaj.org/article/35d1afdf925c4da5986bdea49dfa40aa