Zobrazeno 1 - 10 of 53 pro vyhledávání: '"Guoyi Yan"'
2
Akademický článek
Identification of critical pathways and potential therapeutic targets in poorly differentiated duodenal papilla adenocarcinoma
Autor: Yuanxiang Lu, Wensen Li, Ge Liu, Yongbo Yang, Erwei Xiao, Senmao Mu, Yuqi Guo, Deyu Li, Guoyi Yan
Publikováno v: Cancer Cell International, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Duodenal papilla carcinoma (DPC) is a rare malignancy of the gastrointestinal tract with high recurrence rate, and the pathogenesis of this highly malignant neoplasm is yet to be fully elucidated. This study aims to identify key g
Externí odkaz: https://doaj.org/article/8f6cb48ce2c842ec8461702f3bd9a406
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3
Akademický článek
Enhancement of orbitofrontal and insular cortices responses to spicy perception increases high salt sensation: An event-related potentials study
Autor: Qiang Li, Fang Sun, Guoyi Yan, Hongmei Lang, Zhiming Zhu
Publikováno v: Heart and Mind, Vol 3, Iss 3, Pp 107-112 (2019)
Context: The interplay between taste perception and salt sensation is crucial for salt intake. Our hemodynamic neuroimaging research has shown that the administration of capsaicin (the major spicy component of chili peppers) enhances the metabolic ac
Externí odkaz: https://doaj.org/article/3d4cc84829014f8188cb6329ddc36d10
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5
Identification of Critical Pathways and Potential Key Genes in Poorly Differentiated Pancreatic Adenocarcinoma
Autor: Senmao Mu, Guoyi Yan, Fangyuan Qin, Shaofeng Duan, Deyu Li, Yuanxiang Lu, Yujin Pan, Yaping Zhai, Erwei Xiao, Ge Liu, Dongxiao Li
Publikováno v: OncoTargets and therapy
Yuanxiang Lu,1,2,* Dongxiao Li,3,* Ge Liu,1,4 Erwei Xiao,1 Senmao Mu,1 Yujin Pan,1 Fangyuan Qin,5 Yaping Zhai,5 Shaofeng Duan,6 Deyu Li,1,2 Guoyi Yan1,4 1Department of Hepatobiliary Surgery, Henan Provincial People’s Hospital, People’s Hospital o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01283f7926853c663f0f6fd98c5cdbe
http://europepmc.org/articles/PMC7850576
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6
Identification of critical pathways and potential therapeutic targets in poorly differentiated duodenal papilla adenocarcinoma
Autor: Wensen Li, Deyu Li, Ge Liu, Yuanxiang Lu, Erwei Xiao, Guoyi Yan, Senmao Mu, Yongbo Yang, Yuqi Guo
Publikováno v: Cancer Cell International, Vol 21, Iss 1, Pp 1-10 (2021)
Cancer Cell International
Background Duodenal papilla carcinoma (DPC) is a rare malignancy of the gastrointestinal tract with high recurrence rate, and the pathogenesis of this highly malignant neoplasm is yet to be fully elucidated. This study aims to identify key genes to f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21dc6baa39c6174c2ab82edd2bac6690
https://doaj.org/article/8f6cb48ce2c842ec8461702f3bd9a406
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7
Akademický článek
A comprehensive assessment of heavy metals, VOCs and petroleum hydrocarbon in different soil layers and groundwater at an abandoned Al/Cu industrial site
Autor: Jing Wu, Jinfeng Jiang, Changlin Xu, Yue Cai, Min Li, Yang Yang, Guoyi Yang, Xiang-Zhou Meng, JinMing Leib, Hao Zhangb, Shengwei Zhang
Publikováno v: Ecotoxicology and Environmental Safety, Vol 284, Iss , Pp 116927- (2024)
Compound pollution at industrial sites impedes urban development, especially when there is a lack of understanding about the spatial variations of internal pollution in industrial areas producing light-weight materials. In this study, spatial distrib
Externí odkaz: https://doaj.org/article/9f3c56d975004987b258f8a83c298612
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8
Identification of HDAC6 selective inhibitors: pharmacophore based virtual screening, molecular docking and molecular dynamics simulation
Autor: Yuqi Guo, Fangyuan Qin, Deyu Li, Shaofeng Duan, Ge Liu, Yuanxiang Lu, Xinxin Zhong, Dongxiao Li, Guoyi Yan, Xueqin Wang
Publikováno v: Journal of Biomolecular Structure and Dynamics. 39:1928-1939
HDAC6 regulates the expression and activity of various tumor-related proteins, but currently there is no selective inhibitor targeting HDAC6 for clinical application. In order to discover novel HDAC6 inhibitors, virtual screening methods comprised of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a407867b222278d724128ef6d87e10
https://doi.org/10.1080/07391102.2020.1743760
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9
Enhancement of orbitofrontal and insular cortices responses to spicy perception increases high salt sensation: An event-related potentials study
Autor: Zhiming Zhu, Qiang Li, Fang Sun, Guoyi Yan, Hongmei Lang
Publikováno v: Heart and Mind, Vol 3, Iss 3, Pp 107-112 (2019)
Context: The interplay between taste perception and salt sensation is crucial for salt intake. Our hemodynamic neuroimaging research has shown that the administration of capsaicin (the major spicy component of chili peppers) enhances the metabolic ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d92dea577615392ab08402a522953ed
http://www.heartmindjournal.org/article.asp?issn=2468-6476
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10
Targeting Cysteine Located Outside the Active Site: An Effective Strategy for Covalent ALKi Design
Autor: Chunlan Pu, Shilong Fan, Xueyan Hou, Suke Lan, Deyu Li, Rui Li, Meng Zhou, Lin Yue, Guoyi Yan, Jie Yang, Xinxin Zhong, Huifang Shan
Publikováno v: Journal of medicinal chemistry. 64(3)
Potent inhibitors of ALK are highly desired because of the occurrence of drug resistance. We herein firstly report the development of a rationally designed inhibitor, Con B-1, which can covalently bind to Cys1259, a cysteine located outside the ALK a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef7ad6a72be2a296b97dd687b5f5940
https://pubmed.ncbi.nlm.nih.gov/33471528
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