Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Guoxing, You"'
Autor:
Kai Zhu, Lijun Wang, Yao Xiao, Xiaoyong Zhang, Guoxing You, Yuzhi Chen, Quan Wang, Lian Zhao, Hong Zhou, Gan Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Oxygen is necessary for life and plays a key pivotal in maintaining normal physiological functions and treat of diseases. Hemoglobin-based oxygen carriers (HBOCs) have been studied and developed as a replacement for red blood cells (RBCs) in
Externí odkaz:
https://doaj.org/article/ce1f2b3edd5a4c90887c5d59b28c6d15
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Red blood cell substitutes offer a solution to the problem of blood shortage and side effects of blood transfusion. Hemoglobin-based oxygen carriers (HBOCs) are one of the promising substitutes for red blood cells. Vasoactivity, which refers to the s
Externí odkaz:
https://doaj.org/article/7bc976f4d53c415b9d9754dfaa03074e
Autor:
Bingting Li, Jun Zhang, Ning Ma, Weidan Li, Guoxing You, Gan Chen, Lian Zhao, Quan Wang, Hong Zhou
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 120-130 (2023)
AbstractDoxorubicin (DOX) is an effective chemotherapeutic agent widely used for cancer treatment. However, hypoxia in tumour tissue and obvious adverse effects particularly cardiotoxicity restricts the clinical usage of DOX. Our study is based on th
Externí odkaz:
https://doaj.org/article/c6cffe8d3b3940c889765348a38f8f5e
Autor:
Yan Geng, Xinyi Long, Yuting Zhang, Yupeng Wang, Guoxing You, Wenjie Guo, Gaoming Zhuang, Yuanyuan Zhang, Xiao Cheng, Zhengqiang Yuan, Jie Zan
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Parkinson's disease (PD), characterized by the progressive loss of dopaminergic neurons in the substantia nigra and striatum of brain, seriously threatens human health, and is still lack of effective treatment. Dysregulation of N6
Externí odkaz:
https://doaj.org/article/7deaee7d7ea849f7a2e4446934a22c7b
Autor:
Gan Chen, Chao Ren, Yao Xiao, Yujing Wang, Renqi Yao, Quan Wang, Guoxing You, Mingzi Lu, Shaoduo Yan, Xiaoyong Zhang, Jun Zhang, Yongming Yao, Hong Zhou
Publikováno v:
JHEP Reports, Vol 5, Iss 6, Pp 100718- (2023)
Background & Aims: Sepsis-induced acute liver dysfunction often occurs early in sepsis and can exacerbate the pathology by triggering multiple organ dysfunction and increasing lethality. Nevertheless, our understanding of the cellular heterogeneity a
Externí odkaz:
https://doaj.org/article/d54a44d16ddb4b39b7c3fab6d3e6e9a0
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: High altitude-related hypoxia-induced organ damage significantly impacts people who are exposed to acute high-altitude environment. At present, kidney injury still lacks effective treatment strategies. Iridium nanozymes (Ir-NPs) are a n
Externí odkaz:
https://doaj.org/article/7bd5c800d2ae499b810fe4022144f7a8
Autor:
Jiaming Li, Rongzhi Tan, Jie Wu, Wenjie Guo, Yupeng Wang, Guoxing You, Yuting Zhang, Zhiyong Yu, Yan Geng, Jie Zan, Jianfen Su
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Introduction: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with low 5-year survival rate. Cellular senescence, characterized by permanent and irreversible cell proliferation arrest, plays an important role in tumorig
Externí odkaz:
https://doaj.org/article/a3671548bedd458987943425d5fcf3ff
Autor:
Yuting Zhang, Jie Wu, Guoxing You, Wenjie Guo, Yupeng Wang, Zhiyong Yu, Yan Geng, Qinghua Zhong, Jie Zan, Linbo Zheng
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 6, p 138 (2023)
Background: Alzheimer’s disease (AD) is a common progressive neurodegenerative disease. The Ubiquitin-Protease system (UPS), which plays important roles in maintaining protein homeostasis in eukaryotic cells, is involved in the development of AD. T
Externí odkaz:
https://doaj.org/article/1dd114c49eba4742acbbb1e431ddab72
Autor:
Yao Xiao, Chao Ren, Gan Chen, Pan Shang, Xiang Song, Guoxing You, Shaoduo Yan, Yongming Yao, Hong Zhou
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100244- (2022)
Sepsis-induced acute liver injury often develops in the early stages of sepsis and can exacerbate the pathology by contributing to multiple organ dysfunction and increasing lethality. No specific therapies for sepsis-induced liver injury are currentl
Externí odkaz:
https://doaj.org/article/57e40594c309418b8e92bf89303a1cd6
Autor:
Zongtang Chu, Weidan Li, Guoxing You, Yuzhi Chen, Dong Qin, Peilin Shu, Yujing Wang, Ying Wang, Lian Zhao, Hong Zhou
Publikováno v:
Molecules, Vol 28, Iss 5, p 2050 (2023)
Acute altitude hypoxia represents the cause of multiple adverse consequences. Current treatments are limited by side effects. Recent studies have shown the protective effects of resveratrol (RSV), but the mechanism remains unknown. To address this, t
Externí odkaz:
https://doaj.org/article/307ea1c56cfe4084b203f99994548906