Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Guoxin Hu"'
Autor:
Nong Yu, Shuangming Lin, Xiaojie Wang, Guoxin Hu, Run Xie, Zhipeng Que, Runsheng Lai, Dongbo Xu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundEndoscopic obstruction (eOB) is associated with a poor prognosis in colorectal cancer (CRC). Our study aimed to investigate the association between tumor location and eOB, as well as the prognostic differences among non-endoscopic obstructi
Externí odkaz:
https://doaj.org/article/a0bd93453fe541ce89f68aef1922320a
Autor:
Xiaodan Zhang, Qingqing Li, Xinwu Ye, Qing Chen, Chen Chen, Guoxin Hu, Likang Zhang, Lianguo Chen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: To study the effects of drug-induced CYP2D6 activity inhibition and genetic polymorphisms on fluoxetine metabolism, rat liver microsomes (RLMs) and SD rats were used to investigate the potential drug‒drug interactions (DDIs), and CYP2
Externí odkaz:
https://doaj.org/article/2625b73d6ba7476f96de8edb34321784
Publikováno v:
Journal of Materiomics, Vol 9, Iss 4, Pp 661-672 (2023)
SrTiO3-based oxides have been investigated as a promising n-type thermoelectric material at high temperatures; however, the relatively high thermal conductivity results in inferior thermoelectric performance. The lattice thermal conductivity can be s
Externí odkaz:
https://doaj.org/article/3e3ec1c775a5490abda7b96763f6d06b
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 5, Pp 659-663 (2022)
Objective(s): This study aims to evaluate the catalytic activities of 31 CYP2C19 alleles and their effects on the metabolism of tapentadol in vitro. Materials and Methods: Insect microsomes expressing the CYP2C19 alleles were incubated with 50–1250
Externí odkaz:
https://doaj.org/article/1d071226d96f4fcfad5bf473dc120495
Autor:
Xinru Nie, Yan He, Qiangqiang Shi, Yuqian Liang, Lingling Wei, Pengfei Liang, Xiaolian Chao, Guoxin Hu, Zupei Yang
Publikováno v:
Journal of Advanced Dielectrics, Vol 13, Iss 01 (2023)
Lead-free relaxor ceramics (1 − [Formula: see text])K[Formula: see text]Na[Formula: see text]NbO3 − [Formula: see text]Bi(Mn[Formula: see text]Ni[Formula: see text])O3 ((1 − [Formula: see text] )KNN- [Formula: see text]BMN) with considerable ch
Externí odkaz:
https://doaj.org/article/718e1f455e4040d99fa05fa7b349a9c9
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
The aim of this study is to investigate the effects of CYP3A4 genetic polymorphisms on the metabolism of cyclosporine (CsA) in vitro and identify drugs that interact with CsA. An enzymatic incubation system was developed to evaluate the kinetic param
Externí odkaz:
https://doaj.org/article/d21f847fc4ad48f485377679bf31182c
Autor:
Zhize Ye, Bingbing Chen, Nanyong Gao, Qihui Kong, Xiaoqin Hu, Zhongqiu Lu, Jianchang Qian, Guoxin Hu, Jianping Cai, Bin Wu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
This study aimed 1) to investigate the influence of CYP2D6 variants on the catalyzing of fluvoxamine, and 2) to study the interaction between fluvoxamine and apatinib. An enzymatic reaction system was setup and the kinetic profile of CYP2D6 in metabo
Externí odkaz:
https://doaj.org/article/f2d5609d984b470db4d45a747477102c
Autor:
Lin Chen, Senjun Jin, Min Yang, Chunmei Gui, Yingpu Yuan, Guangtao Dong, Weizhong Zeng, Jing Zeng, Guoxin Hu, Lujun Qiao, Jinhua Wang, Yonglin Xi, Jian Sun, Nan Wang, Minmin Wang, Lifeng Xing, Yi Yang, Yan Teng, Junxia Hou, Qiaojie Bi, Huabo Cai, Gensheng Zhang, Yucai Hong, Zhongheng Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Sepsis is a leading cause of morbidity and mortality in the intensive care unit, which is caused by unregulated inflammatory response leading to organ injuries. Ulinastatin (UTI), an immunomodulatory agent, is widely used in clinical practice and is
Externí odkaz:
https://doaj.org/article/b05f1ff99f2e42f9b0ebf7b4b5c4780d
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The aim of this study was to 1) investigate the effects of 27 CYP3A4 variants on the metabolism of osimertinib and 2) study the interactions between osimertinib and others as well as the underlying mechanism. A recombinant human CYP3A4 enzymatic incu
Externí odkaz:
https://doaj.org/article/04e3715f44b74255bdada248224e038f
Autor:
Hanyang Gao, Kunkun Pei, Guoxin Hu, Wenxing Liu, Aihua Meng, Hongcheng Wang, Huifeng Shao, Wenxin Li
Publikováno v:
Ultrasonics Sonochemistry, Vol 83, Iss , Pp 105934- (2022)
CO2-expanded organic solvent is a kind of important fluid medium and has broad applications in chemical industry, environmental protection and other fields. Ultrasonic cavitation in gas expanded liquids (GXLs) is conducive to enhancing mass transfer
Externí odkaz:
https://doaj.org/article/2aa12e1a7200413e8b45585375299023