Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Guoxian Ding"'
Publikováno v:
Experimental Gerontology, Vol 197, Iss , Pp 112594- (2024)
Background: Frailty increases the incidence of geriatric syndromes and even the risk of death in old adults. However, the diagnostic criteria for frailty are inconsistent because of complex pathological processes and diverse clinical manifestations.
Externí odkaz:
https://doaj.org/article/ace01614fd1644ffac7a1f1a2540519d
Autor:
Shan Lv, Qianjin Shen, Hengzhen Li, Qun Chen, Wenqing Xie, Yusheng Li, Xiaodong Wang, Guoxian Ding
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
IntroductionCalorie restriction (CR) is an important direction for the delay of sarcopenia in elderly individuals. However, the specific mechanisms of CR against aging are still unclear.MethodsIn this study, we used a CR model of elderly mice with mu
Externí odkaz:
https://doaj.org/article/c443f446cf65431bbe744d56ca68030b
Autor:
Yan Guo, Guoqin Zhu, Fengliang Wang, Haoyu Zhang, Xin Chen, Yan Mao, Yifan Lv, Fan Xia, Yi Jin, Guoxian Ding, Jing Yu
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Frailty is a critical aging-related syndrome but the underlying metabolic mechanism remains poorly understood. The aim of this study was to identify novel biomarkers and reveal potential mechanisms of frailty based on the integrated analysis of metab
Externí odkaz:
https://doaj.org/article/c840fe44b44f45e386e453d35a6ca1af
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
To explore the correlation between Fried Frailty Phenotype (FFP) and the muscle thickness and quality of local muscle, and to provide a reasonable basis for the application of ultrasound measurement in the frailty assessment. A total of 150 people (a
Externí odkaz:
https://doaj.org/article/3407c688ac1a44a497788a112ac1e854
Autor:
Jing Yu, Yifan Lv, Fengliang Wang, Xiaocen Kong, Wenjuan Di, Juan Liu, Yunlu Sheng, Shan Lv, Guoxian Ding
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Objective: Long-term dysregulation of energy balance is the key component of the obesity epidemic. Given the harm of central obesity and the discovery that beige cells appear within white adipose tissue (WAT), enhancing the energy-expending or “bro
Externí odkaz:
https://doaj.org/article/83bf0998c042489180c4dffa9026887b
Autor:
Hui Yang, Huanhuan Chen, Hongwei Guo, Wen Li, Jinmei Tang, Bojin Xu, Minne Sun, Guoxian Ding, Lin Jiang, Dai Cui, Xuqin Zheng, Yu Duan
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120133 (2015)
Polychlorinated biphenyls (PCBs) can severely interfere with multiple animals and human systems. To explore the molecular mechanisms underlying 2, 3', 4, 4', 5- pentachlorobiphenyl (PCB118)-induced thyroid dysfunction, Fischer rat thyroid cell line-5
Externí odkaz:
https://doaj.org/article/bc20c52ff823441893765f193ca53abf
Autor:
Long Wang, Juan Liu, Aisen Zhang, Peng Cheng, Xiao Zhang, Shan Lv, Lin Wu, Jing Yu, Wenjuan Di, Juanmin Zha, Xiaocen Kong, Hanmei Qi, Yi Zhong, Guoxian Ding
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40056 (2012)
BACKGROUND: Inhibition of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is being pursued as a new therapeutic approach for the treatment of obesity and metabolic syndrome. Therefore, there is an urgent need to determine the effect of 11β-HSD1
Externí odkaz:
https://doaj.org/article/684592fe344c42b597207956ba08999f
Autor:
Jingning Liu, Fangqiao Lv, Wen Sun, Chunxiang Tao, Guoxian Ding, Andrew Karaplis, Edward Brown, David Goltzman, Dengshun Miao
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002294 (2011)
Patients with neonatal severe hyperparathyroidism (NSHPT) are homozygous for the calcium-sensing receptor (CaR) mutation and have very high circulating PTH, abundant parathyroid hyperplasia, and severe life-threatening hypercalcemia. Mice with homozy
Externí odkaz:
https://doaj.org/article/8be628aad0114554a61855dfb7716613
Autor:
Yuxin Zou, Lijun Wei, Xinyu Qi, Jia Fang, Daowen Zhang, Runqing Shi, Wei Liu, Yu Fu, Yunlu Sheng, Yifan Lv, Fan Xia, Guoxian Ding, Yu Duan
Background and aim Skeletal muscle (SM) has been shown as a target of thyroid hormones (THs). However, the status and effectiveness of thyroid hormones transporters (THTs) and deiodinases in thyroid hormones signaling system (TH signaling) during agi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c62acc78a49b89f18fbdc5617cb798e
https://doi.org/10.21203/rs.3.rs-2876675/v1
https://doi.org/10.21203/rs.3.rs-2876675/v1
Autor:
Xiong Li, Jingwen Liu, Yan Zhou, Luman Wang, Yifan Wen, Kun Ding, Lu Zou, Xia Liu, Aiping Li, Yun Wang, Heling Fu, Min Huang, Guoxian Ding, Jianwei Zhou
Publikováno v:
International Journal of Biological Sciences. 18:5503-5521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a4dd9ba10256ea1cac831d3f341311c
https://doi.org/10.7150/ijbs.72751
https://doi.org/10.7150/ijbs.72751