Zobrazeno 1 - 10
of 378
pro vyhledávání: '"Guowen LIU"'
Autor:
Lingxue Ju, Qi Shao, Zhiyuan Fang, Erminio Trevisi, Meng Chen, Yuxiang Song, Wenwen Gao, Lin Lei, Xinwei Li, Guowen Liu, Xiliang Du
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background During the transition period, excessive negative energy balance (NEB) lead to metabolic disorders and reduced milk yield. Rumen microbes are responsible for resolving plant material and producing volatile fatty acids (VFA), which
Externí odkaz:
https://doaj.org/article/49f2bbfb1ff64247a0a68c5a02cc445a
Autor:
Xiliang Du, Mingchao Liu, Erminio Trevisi, Lingxue Ju, Yuting Yang, Wenwen Gao, Yuxiang Song, Lin Lei, Majigsuren Zolzaya, Xinwei Li, Zhiyuan Fang, Guowen Liu
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 10, Pp 8629-8641 (2024)
ABSTRACT: Bile acids are cholesterol-derived molecules that are primarily produced in the liver. In nonruminants with fatty liver, overproduction of bile acids is associated with liver injury. During the transition period, fatty liver is a metabolic
Externí odkaz:
https://doaj.org/article/24a7652dba07430cb1b7bd51430557fe
Autor:
Guojin Li, Liguang Cao, Kai Liu, Yifei Dong, Zifeng Yang, Jianchun Luo, Wenrui Gao, Lin Lei, Yuxiang Song, Xiliang Du, Xinwei Li, Wenwen Gao, Guowen Liu
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 10, Pp 8494-8507 (2024)
ABSTRACT: Mitochondrial dysfunction has been reported to occur in the mammary gland of dairy cows suffering from ketosis. Prohibitin 2 (PHB2) plays a crucial role in regulating mitophagy, which clears impaired mitochondria to maintain normal mitochon
Externí odkaz:
https://doaj.org/article/2bbdfb2bfbd945e1b6d8c9fc406c02fb
Autor:
Wenwen Gao, Yanxi Wang, Siyu Liu, Guojin Li, Qi Shao, Cai Zhang, Liguang Cao, Kai Liu, Wenrui Gao, Zifeng Yang, Yifei Dong, Xiliang Du, Lin Lei, Guowen Liu, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 5, Pp 3127-3139 (2024)
ABSTRACT: During the perinatal period, dairy cows undergo negative energy balance, resulting in elevated circulating levels of nonesterified fatty acids (NEFA). Although increased blood NEFA concentrations are a physiological adaptation of early lact
Externí odkaz:
https://doaj.org/article/0f2ff16940d14a75b1e1623d11f43490
Autor:
Xiliang Du, Meng Chen, Zhiyuan Fang, Qi Shao, Hao Yu, Xue Hao, Xinxing Gao, Lingxue Ju, Chenxu Li, Yuting Yang, Yuxiang Song, Lin Lei, Guowen Liu, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 5, Pp 3269-3279 (2024)
ABSTRACT: The aim of the present study was to investigate the activity of AMPK and mTORC1 as well as TFEB transcriptional activity and autophagy-lysosomal function in the liver of dairy cows with mild fatty liver (FL) and cows with moderate FL. Liver
Externí odkaz:
https://doaj.org/article/22e5ba860cda485ebe33398b8f462d68
Publikováno v:
地质科技通报, Vol 43, Iss 2, Pp 62-74 (2024)
Objective The analysis of pore structure and movable fluid distribution characteristics is the key element of reservoir research and is also the focus and hotspot of current research. It is of great significance for exploring tight sandstone oil and
Externí odkaz:
https://doaj.org/article/5ec71bdbccfb4fc0bff37c8318db8239
Autor:
Qingyun Zhu, Qiuzi Dai, Lei Zhao, Chang Zheng, Qinyuan Li, Zigao Yuan, Lulu Li, Zhuoye Xie, Zixuan Qiu, Wenjun Huang, Guowen Liu, Xuyu Zu, Bizhu Chu, Yuyang Jiang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract PARP inhibitors and HDAC inhibitors have been approved for the clinical treatment of malignancies, but acquired resistance of or limited effects on solid tumors with a single agent remain as challenges. Bioinformatics analyses and a combinat
Externí odkaz:
https://doaj.org/article/130f5bf9dcba44a29bcf23396af299cf
Autor:
Zhiyuan Fang, Xiuhuan Jiang, Shu Wang, Wenjun Tai, Qianming Jiang, Juan J. Loor, Hao Yu, Xue Hao, Meng Chen, Qi Shao, Yuxiang Song, Lin Lei, Guowen Liu, Xiliang Du, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 1, Pp 612-627 (2024)
ABSTRACT: Excessive free fatty acid (FFA) oxidation and related metabolism are the major cause of oxidative stress and liver injury in dairy cows during the early postpartum period. In nonruminants, activation of transcription factor EB (TFEB) can im
Externí odkaz:
https://doaj.org/article/ddb15f43ff004d37b8117c19849cac12
Autor:
Chenchen Zhao, Jinxia Li, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu, Lin Lei, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 12, Pp 9186-9199 (2023)
ABSTRACT: When ketosis occurs, supraphysiological concentrations of nonesterified fatty acids (NEFA) display lipotoxicity and are closely related to the occurrence of hepatic lipid accumulation, oxidative stress, and inflammation, resulting in hepati
Externí odkaz:
https://doaj.org/article/cdf4a48c71664b939110998cc65b85cf
Autor:
Yuchen Yang, Shang Jiang, Jing Yang, Xiancheng Feng, Chao Wang, Kexin Wang, Wenwen Gao, Xiliang Du, Lin Lei, Zhe Wang, Guowen Liu, Yuxiang Song, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 11, Pp 8005-8016 (2023)
ABSTRACT: Dairy cows have high incidence of ketosis during perinatal. According to our previous studies, elevated ketone bodies (mainly β-hydroxybutyrate, BHB) in the peripheral blood are believed to contribute to the impairment of neutrophils mobil
Externí odkaz:
https://doaj.org/article/f80fb336c4c04dbf9adda60a665538ca